Y Yang, M Bao, JW Yoon - Diabetes, 2001 - Am Diabetes Assoc T-cell–mediated autoimmune diabetes in nonobese diabetic (NOD) mice is closely
associated with natural killer T (NKT)-cell deficiency. To determine whether
intrinsic defects of the T-cell lineage contribute to the pathogenesis of ... Cited by 29 - Related articles - BL Direct - All 6 versions
A Rocha-Campos, R Melki, R Zhu, N Deruytter … - DIABETES-NEW YORK-, 2006 - 万方数据资源系统 Defective invariant natural killer T-cells (iNKT cells) have been implicated in
the etiology of type 1 diabetes in nonobese diabetic (NOD) mice. In a genome
scan of a cross between NOD and C57BL/6 mice, the most significant locus ... Cited by 17 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org M Falcone, F Facciotti, N Ghidoli, P Monti, S … - The Journal of Immunology, 2004 - Am Assoc Immnol The immunoregulatory function of NKT cells is crucial for prevention of
autoimmunity. The prototypical NKT cell Ag -galactosylceramide is not present in
mammalian cells, and little is known about the mechanism responsible for ... Cited by 41 - Related articles - BL Direct - All 4 versions
S Thiessen, P Serra, A Amrani, J Verdaguer, … - Diabetes, 2002 - Am Diabetes Assoc For poorly understood reasons, the development of autoimmune diabetes in humans
and mice is dominantly inhibited by major histocompatibility complex (MHC) class
II molecules with diverse antigen-binding sites. We have previously shown ... Cited by 13 - Related articles - BL Direct - All 4 versions
YC Kudva, G Rajagopalan, R Raju, RS … - Human Immunology, 2002 - Elsevier To evaluate the contributions of DR3 and DQ8 to the etiopathogenesis of type 1
diabetes in a diabetes-predisposing milieu, we developed human leukocyte antigen
(HLA) transgenic mice on the nonobese diabetic (NOD) background in the ... Cited by 14 - Related articles - All 4 versions
- ►oxfordjournals.org LD Poulton, MJ Smyth, CG Hawke, P Silveira, … - International Immunology, 2001 - Jpn Soc Immunol Defects in NK and NKT cell activities have been implicated in the etiology of
type 1 (autoimmune) diabetes in NOD mice on the basis of experiments performed
using surrogate phenotypes for the identification of these lymphocyte ... Cited by 91 - Related articles - BL Direct - All 3 versions
[CITATION] Leite-De-Moraes M, Gouarin C, Zhu R, Hameg A, Nakayama T, Taniguchi M, Lepault F, Lehuen A …
- ►jimmunol.org MA Jordan, JM Fletcher, D Pellicci, AG Baxter - The Journal of Immunology, 2007 - Am Assoc Immnol Invariant NKT cells play a critical role in controlling the strength and
character of adaptive immune responses. We have previously reported deficiencies
in the numbers and function of NKT cells in the NOD mouse strain, which is ... Cited by 19 - Related articles - BL Direct - All 6 versions
- ►cell.com L Beaudoin, V Laloux, J Novak, B Lucas, A … - Immunity, 2002 - Elsevier To determine the precise regulatory effect of NKT cells on CD4 + T cells
involved in autoimmune diabetes, we developed an in vivo model in which
transferred naive transgenic T cells are stimulated by their antigen in the ... Cited by 83 - Related articles - BL Direct - All 7 versions
- ►oxfordjournals.org N Baur, G Nerz, A Nil, K Eichmann - International Immunology, 2001 - Jpn Soc Immunol The generation of thymic NK1.1 + ßT (NKT) cells involves positive selection of
cells enriched for V 14/V ß 8 TCR by CD1d MHC class I molecules. However, it
has not been determined whether positive selection is preceded by pre-TCR- ... Cited by 3 - Related articles - BL Direct - All 3 versions
