CD Major, BA Wolf - Diabetes, 2001 - Am Diabetes Assoc Cytokines have been shown to have dramatic effects on pancreatic islets and
insulin-secreting β-cell lines. It is well established that cytokines such as
interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and ... Cited by 27 - Related articles - BL Direct - All 6 versions
MA Nikulina, N Sandhu, Z Shamim, NA … - Cytokine, 2003 - Elsevier The stress-activated protein kinase c-Jun NH 2 -terminal kinase (JNK) is a
central signal for interleukin-1β (IL-1β)-induced apoptosis in
insulin-producing β-cells. The cell-permeable peptide inhibitor of JNK ... Cited by 20 - Related articles - All 3 versions
RR Prattali, GC Barreiro, CT Caliseo, FY … - FEBS letters, 2005 - Elsevier In this study, we demonstrate that pretreatment with aspirin inhibits GH-induced
insulin resistance. GH was observed to lead to serine phosphorylation of IRS-1,
a phenomenon which was reversed by aspirin in liver, muscle and WAT in ... Cited by 14 - Related articles - All 4 versions
NA Andersen, CM Larsen, T Mandrup- … - Diabetologia, 2000 - Springer The cytokine interleukin-1b (IL-1b) is cytotoxic to rat [1] and human pancreatic
beta cells in synergy with tumour necrosis factor-a (TNFa) and interfer- on-g
(IFNg) [2, 3]. Inactivating IL-1b by treatment with soluble IL-1b receptors ... Cited by 17 - Related articles - BL Direct - All 3 versions
OP McGuinness, A Mari - Metabolism, 1997 - Elsevier We evaluated the validity of the traditional method of assessment of the speed
of insulin action during a euglycemic-hyperinsulinemic clamp. We first estimated
the error of Steele's model on glucose uptake in these experimental ... Cited by 6 - Related articles - BL Direct - All 6 versions
I Chang, N Cho, S Kim, JY Kim, E Kim, JE … - 免疫学杂志, 2004 - journal.shouxi.net 【摘要】 We studied the intracellular events associated with pancreatic cell
apoptosis by IFN- /TNF- synergism. IFN- /TNF- treatment of MIN6N8 insulinoma
cells increased the amplitude of high voltage-activated Ca 2+ currents, ... Cited by 9 - Related articles - Cached
- ►jbc.org C Bonny, A Oberson, M Steinmann, DF … - Journal of Biological Chemistry, 2000 - ASBMB IB1/JIP-1 is a scaffold protein that interacts with upstream components of the
c-Jun N-terminal kinase (JNK) signaling pathway. IB1 is expressed at high levels
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A Ammendrup, A Maillard, K Nielsen, NA … - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc To characterize the differentiation events that selec- tively target
insulin-producing cells to interleukin (IL)- 1 –induced apoptosis, we studied
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- ►ahajournals.org PO Prada, MM Okamoto, LNS Furukawa, UF … - Hypertension, 2000 - Am Heart Assoc Abstract—Because of conflicting results in the literature, further studies are
needed to confirm an association between the degree of salt consumption and
insulin sensitivity. The aim of this study was to measure insulin ... Cited by 37 - Related articles - BL Direct - All 7 versions
