- ►diabetesjournals.org JM Lin, H Ortsäter, H Fakhrai-Rad, J Galli, H Luthman, … - Diabetes, 2001 - Am Diabetes Assoc The major diabetes quantitative trait locus (Niddm1), which segregates in crosses between GK
rats affected with spontaneous type 2–like diabetes and normoglycemic F344 rats, encodes at
least two different diabetes susceptibility genes. Congenic strains for the two subloci ( ... Cited by 14 - Related articles - BL Direct - All 5 versions
[CITATION] Pivotal role of cAMP in the acute restitution of defective glucose-stimulated insulin …
- ►diabetesjournals.org [PDF] J Galli, H Fakhrai-Rad, A Kamel, C Marcus, S Norgren, … - Diabetes, 1999 - Am Diabetes Assoc Genetic studies of the type 2 diabetes–like GK rat have revealed several susceptibility loci for
the compound diabetes phenotype. Congenic strains were established for N iddm 1, the major
quantitative trait locus (QTL) for postprandial glucose levels, by transfer of GK alleles onto ... Cited by 46 - Related articles - BL Direct - All 4 versions
MH Giroix, C Saulnier, B Portha - Diabetologia, 1999 - Springer One of the major characteristic features of Type II (non-insulin-dependent) diabetes mellitus is
the de- creased ability of pancreatic beta cells to release insu- lin in response to stimulation by
the carbohydrate d-glucose, the most potent physiological insulin se- cretagogue. Such a ... Cited by 18 - Related articles - BL Direct - All 4 versions
TK Watanabe, S Okuno, T Ono, Y Yamasaki, K … - Clinical and experimental … - ncbi.nlm.nih.gov 1. Whole-genome scans have identified Dmo1 as a major quantitative trait locus for dyslipidaemia
and obesity in the Otsuka Long Evans Tokushima Fatty (OLETF) rat. 2. We have produced congenic
rats for the Dmo1 locus through successive back-cross breeding with diabetic OLETF rats. ... Cited by 8 - Related articles - BL Direct - All 3 versions
H Päivärinne, H Kainulainen - Acta Diabetologica, 2001 - Springer Abstract We have identified a novel gene product differen- tially expressed in skeletal muscle
in a rat diabetes model induced by streptozotocin. Northern blot analysis showed expression
in all studied tissues and a marked down-regula- tion in insulin-sensitive tissues (skeletal ... Cited by 8 - Related articles - BL Direct - All 2 versions
ZC Ling, C Hong-Lie, CG Ostenson, S … - DIABETES-NEW …, 2001 - Am Diabetes Assoc Insulin secretion and glucose metabolism were compared in pancreatic islets from type 2 diabetic
GK rats treated with phlorizin or vehicle. Treatment of control and GK rats with phlorizin for 30
days did not affect body weight, islet glucose utilization, or islet glucose oxidation. In ... Cited by 15 - Related articles - BL Direct - All 6 versions
