- ►diabetesjournals.org MMW Chong, HE Thomas, TWH Kay - Diabetes, 2001 - Am Diabetes Assoc Proinflammatory cytokines, including γ-interferon (IFN-γ), have been
implicated in the destruction of β-cells in autoimmune diabetes. IFN-γ
signaling is transient in some cell types, but there is indirect evidence ... Cited by 32 - Related articles - BL Direct - All 4 versions
[CITATION] Interferon signaling in pancreatic-cells is persistent but can be terminated by overexpression …
A Victoria - DIABETES, 2001 - Am Diabetes Assoc (IFN- ), have been implicated in the destruction of -cells in autoimmune
diabetes. IFN- signaling is tran- sient in some cell types, but there is
indirect evidence that it may be prolonged in -cells. In this study, we ... Related articles
- ►endojournals.org PT Fueger, JC Schisler, D Lu, DA Babu, RG … - Molecular Endocrinology, 2008 - Endocrine Soc Both major forms of diabetes involve a decline in β-cell mass, mediated by
autoimmune destruction of insulin-producing cells in type 1 diabetes and by
increased rates of apoptosis secondary to metabolic stress in type 2 ... Cited by 9 - Related articles - BL Direct - All 5 versions
- ►endocrinology-journals.org GF Anhe, TCA Nogueira, JE Nicoletti-Carvalho … - Journal of Endocrinology, 2007 - Soc Endocrinology During pregnancy, the maternal endocrine pancreas undergoes, as a consequence of
placental lactogens and prolactin (PRL) action, functional changes that are
characterized by increased glucose-induced insulin secretion. After ... Cited by 9 - Related articles - BL Direct - All 2 versions
SG Rønn, N Billestrup, T Mandrup-Poulsen - Diabetes, 2007 - Am Diabetes Assoc The pathogenesis of type 1 diabetes is not clearly understood, but it is
generally accepted that type 1 diabetes is an immune-mediated disease caused by
inflammation in the islets of Langerhans. Infiltrating macrophages release ... Cited by 15 - Related articles - BL Direct - All 4 versions
SC Crepaldi-Alves, EM Carneiro, JR … - Brazilian Journal of Medical and Biological Research, 1997 - SciELO Brasil We studied the synergistic effect of glucose and prolactin (PRL) on insulin
secretion and GLUT2 expression in cultured neonatal rat islets. After 7 days in
culture, basal insulin secretion (2.8 mM glucose) was similar in control ... Cited by 10 - Related articles - Cached - BL Direct - All 9 versions
- ►nih.gov JY Lee, O Gavrilova, B Davani, R Na, GW … - BBA-Molecular Cell Research, 2007 - Elsevier In insulinoma cell lines proliferation and insulin gene transcription are
stimulated by growth hormone and prolactin, which convey their signals through
the transcription factors Stat5a and 5b (referred to as Stat5). However, ... Cited by 11 - Related articles - All 4 versions
- ►endojournals.org M Jackerott, YC Lee, K Mollgard, H Kofod, J … - Endocrinology, 2006 - Endocrine Soc Trefoil factors (TFFs) 1, 2, and 3 are expressed in mucosal epithelia. TFFs are
particular abundant in the intestine in which they play a crucial role in
maintenance and restitution of the epithelium. Because pancreas ... Cited by 12 - Related articles - BL Direct - All 4 versions
AE Karlsen, PE Heding, H Frobøse, SG Rønn, M … - Diabetologia, 2004 - Springer Aims/hypothesis. The proinflammatory cytokine IL-1β induces apoptosis in
pancreatic beta cells via path- ways dependent on nuclear factor-κB (NF-κB),
mito- gen-activated protein kinase, and protein kinase C. We recently ... Cited by 25 - Related articles - All 3 versions
