A García-Ocaña, RC Vasavada, A Cebrian, V … - Diabetes, 2001 - Am Diabetes Assoc Recent advances in human islet transplantation have highlighted the need for
expanding the pool of ß-cells available for transplantation. We have developed
three transgenic models in which growth factors (hepatocyte growth factor ... Cited by 80 - Related articles - BL Direct - All 4 versions
A Garcıáa, RC Vasavada, A Cebrian, V Reddy … - Diabetes, 2001 - Am Diabetes Assoc Recent advances in human islet transplantation have highlighted the need for
expanding the pool of -cells available for transplantation. We have developed
three transgenic models in which growth factors (hepatocyte growth factor ... Cited by 2 - Related articles
- ►jbc.org A Garcia-Ocana, KK Takane, MA Syed, WM … - Journal of Biological Chemistry, 2000 - ASBMB Hepatocyte growth factor (HGF) is produced in pancreatic mesenchyme-derived
cells and in islet cells. In vitro, HGF increases the insulin content and
proliferation of islets. To study the role of HGF in the islet in vivo, we ... Cited by 135 - Related articles - BL Direct - All 4 versions
- ►jbc.org RC Vasavada, A Garcia-Ocana, WS Zawalich, … - Journal of Biological Chemistry, 2000 - ASBMB The factors that regulate pancreatic beta cell proliferation are not well
defined. In order to explore the role of murine placental lactogen (PL)-I
(mPL-I) in islet mass regulation in vivo, we developed transgenic mice in ... Cited by 86 - Related articles - BL Direct - All 4 versions
- ►endocrinology-journals.org [PDF] S Gahr, M Merger, LC Bollheimer, CG … - Journal of molecular endocrinology, 2002 - Soc Endocrinology We investigated the role of hepatocyte growth factor (HGF) in β-cell growth and
its complex intracellular signal transduction pathways. Cell proliferation was
measured in the β-cell line INS-1 using [3H]thymidine incorporation. ... Cited by 35 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org A Cebrian, A García-Ocaña, KK Takane, D … - Diabetes, 2002 - Am Diabetes Assoc Pancreatic β-cell survival is critical in the setting of diabetes as well as in
islet transplantation. Transgenic mice overexpressing parathyroid
hormone-related protein (PTHrP) targeted to β-cells using the rat insulin ... Cited by 37 - Related articles - BL Direct - All 4 versions
T Otonkoski, V Cirulli, M Beattie, MI Mally, G … - Endocrinology, 1996 - Endocrine Soc Page 1. 0013.7227/96/$03 00/O Endocrinology CopyrIght 6 1996 by The Endocrine
Society A Role for Hepatocyte Growth Factor/Scatter Factor in ... Cited by 103 - Related articles - BL Direct - All 5 versions
Y Fujinaka, D Sipula, A Garcia-Ocaña, RC … - Diabetes, 2004 - Am Diabetes Assoc Transgenic overexpression of either parathyroid hormone-related peptide (PTHrP)
or mouse placental lactogen type 1 (mPL1) in pancreatic β-cells, using the rat
insulin II promoter (RIP), results in islet hyperplasia either through ... Cited by 27 - Related articles - BL Direct - All 5 versions
- ►jbc.org A Garcia-Ocana, KK Takane, VT Reddy, JC … - Journal of Biological Chemistry, 2003 - ASBMB Hepatocyte growth factor (HGF) increases beta cell proliferation and function in
rat insulin promoter (RIP)-targeted transgenic mice. RIP-HGF mouse islets also
function superiorly to normal islets in a transplant setting. Here, we ... Cited by 55 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org J Roccisana, V Reddy, RC Vasavada, JA … - Diabetes, 2005 - Am Diabetes Assoc Overexpression of hepatocyte growth factor (HGF) in the ß-cell of transgenic
mice enhances ß-cell proliferation, survival, and function. In the current
studies, we have used conditional ablation of the c-met gene to uncover the ... Cited by 31 - Related articles - All 6 versions