- ►liptapro.com [PDF] J Wang, S Obici, K Morgan, N Barzilai, Z Feng, … - Diabetes, 2001 - Am Diabetes Assoc In common forms of obesity, hyperphagia, hyperinsulinemia, and hyperleptinemia
coexist. Here, we demonstrate rapid induction of insulin and leptin resistance
by short-term overfeeding. After 3 and 7 days on the assigned diet regimen, ... Cited by 131 - Related articles - BL Direct - All 14 versions
K Morgan, S Obici, L Rossetti - Journal of Biological Chemistry, 2004 - ASBMB Central administration of the long-chain fatty acid oleic acid inhibits food
intake and glucose production in rats. Here we examined whether short term
changes in nutrient availability can modulate these metabolic and ... Cited by 55 - Related articles - BL Direct - All 4 versions
S Obici, Z Feng, K Morgan, D Stein, G … - Diabetes, 2002 - Am Diabetes Assoc The hypothalamus and other regions within the central nervous system (CNS) link
the sensing of nutrients to the control of metabolism and feeding behavior.
Here, we report that intracerebroventricular (ICV) administration of the ... Cited by 218 - Related articles - BL Direct - All 5 versions
- ►nih.gov S Obici, Z Feng, J Tan, LS Liu, G Karkanias, L … - Journal of Clinical Investigation, 2001 - Am Soc Clin Investig Energy balance and insulin action are tightly coregulated. Leptin regulates
energy intake and expenditure partly by modulation of the melanocortin pathway
in the hypothalamus. Here we demonstrate potent effects of the melanocortin ... Cited by 182 - Related articles - BL Direct - All 7 versions
- ►jbc.org LS Liu, GB Karkanias, JC Morales, M Hawkins, … - Journal of Biological Chemistry, 1998 - ASBMB Acute intravenous infusions of leptin markedly alter hepatic glucose fluxes
(Rossetti, L., Massillon, D., Barzilai, N., Vuguin, P., Chen, W., Hawkins, M.,
Wu, J., and Wang, J. (1997) J. Biol. Chem. 272, 27758-22763). Here we ... Cited by 134 - Related articles - BL Direct - All 6 versions
- ►endojournals.org L Rossetti - Endocrinology, 2000 - Endocrine Soc The prevalence of obesity and type 2 diabetes mellitus has increased
concomitantly with the introduction of nutrients with high caloric density and
more sedentary lifestyle in western societies. The tight association ... Cited by 89 - Related articles - BL Direct - All 3 versions
- ►physiology.org GR Steinberg, DJ Dyck - American Journal of Physiology- Endocrinology And …, 2000 - Am Physiological Soc Direct evidence for leptin resistance in peripheral tissues such as skeletal
muscle does not exist. Therefore, we investigated the effects of different
high-fat diets on lipid metabolism in isolated rat soleus muscle and ... Cited by 54 - Related articles - BL Direct - All 3 versions
TKT Lam, GJ Schwartz, L Rossetti… - Nature neuroscience, 2005 - dept.wofford.edu Energy homeostasis is maintained by multiple mechanisms that gather information
on the body's nutritional status and make appro- priate behavioral and metabolic
responses to changes in fuel avail- ability. Although it is clear that ... Cited by 119 - Related articles - All 5 versions
S Obici, Z Feng, G Karkanias, DG Baskin, L … - Nature neuroscience, 2002 - nature.com We investigated the role of hypothalamic insulin signaling in the regulation of
energy balance and insulin action in rats through selective decreases in insulin
receptor expression in discrete hypothalamic nuclei. We generated an ... Cited by 228 - Related articles - BL Direct - All 4 versions
