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Scholar Results 1 - 10 of about 101 related to Shen: PKCδ Activation. (0.12 sec) 

PKCδ Activation

- diabetesjournals.org
S Shen, A Alt, E Wertheimer, M Gartsbein, T … - Diabetes, 2001 - Am Diabetes Assoc
Insulin and insulin-like growth factor-1 (IGF-1) are members of the family of
the insulin family of growth factors, which activate similar cellular downstream
pathways. In this study, we analyzed the effects of insulin and IGF-1 on ...
Cited by 39 - Related articles - BL Direct - All 6 versions

Protein kinase C {delta} mediates insulin-induced glucose transport in primary cultures of rat …

- endojournals.org
L Braiman, A Alt, T Kuroki, M Ohba, A Bak, … - Molecular Endocrinology, 1999 - Endocrine Soc
Insulin activates certain protein kinase C (PKC) isoforms that are involved in
insulin-induced glucose transport. In this study, we investigated the
possibility that activation of PKC by insulin participates in the mediation ...
Cited by 67 - Related articles - BL Direct - All 6 versions

The regulation of skin proliferation and differentiation in the IR null mouse: implications for …

- endojournals.org
E Wertheimer, N Spravchikov, M Trebicz, M … - Endocrinology, 2001 - Endocrine Soc
Impaired wound healing of skin is one of the most serious complications of
diabetes. However, the pathogenesis of this process is not known, and it is
unclear whether impaired insulin signaling could directly affect skin ...
Cited by 35 - Related articles - BL Direct - All 3 versions

Differential roles of insulin receptor and insulin-like growth factor-1 receptor in …


E Wertheimer, M Trebicz, T Eldar, M … - Journal of Investigative Dermatology, 2000 - nature.com
The insulin receptor and the insulin-like growth factor-1 receptor are widely
expressed tyrosine kinases that mediate insulin and insulin-like growth factor-1
signaling. Both receptors are expressed in many cells in which insulin ...
Cited by 39 - Related articles - BL Direct - All 5 versions

Involvement of Na, K () ATPase in the mitogenic effect of insulin-like growth factor-I on …


T Matsuda, Y Murata, K Tanaka, R Hosoi, M … - J Neurochem, 1996 - interscience.wiley.com
Abstract: We have previously reported that insulin/insulin-like growth factor
(IGF)-I induced the α1 isoform of Na + ,K + -ATPase in cultured astrocytes. In
this study the effects of insulin/IGF-I on Na + ,K + -ATPase activity and ...
Cited by 17 - Related articles - BL Direct - All 4 versions

The role of protein kinase C isoforms in insulin action.


P Formisano, F Beguinot - Journal of endocrinological investigation, 2001 - ncbi.nlm.nih.gov
Insulin action on target tissues is mediated by specific tyrosine kinase
receptors. Upon ligand binding insulin receptors autophosphorylate and
phosphorylate intracellular substrates on tyrosine residues. These early ...
Cited by 20 - Related articles - BL Direct - All 2 versions

Differential regulation of α6β4 integrin by PKC isoforms in murine skin keratinocytes


A Alt, M Gartsbein, M Ohba, T Kuroki, T … - Biochemical and Biophysical Research …, 2004 - Elsevier
In mammalian epidermis, α6β4 integrin is expressed exclusively on the basal
layer localized to the hemidesmosomes, where it interacts extracellularly with
the laminin-5 ligand. During differentiation, loss of α6β4 is associated ...
Cited by 9 - Related articles - All 5 versions

Angiotensin II type 1 receptor-mediated increase in cytosolic Ca2+ and proliferation in …


M Kuwahara, T Miyaji, H Tsubone, M … - European journal of pharmacology, 2000 - Elsevier
We investigated the Ca 2+ signaling pathways of the response to angiotensin II
in pleural mesothelial cells and the role of these Ca 2+ signaling pathways in
mesothelial cell proliferation. Rat pleural mesothelial cells were ...
Cited by 11 - Related articles - All 3 versions

Insulin Induces Specific Interaction between Insulin Receptor and Protein Kinase C {{delta}} …

- endojournals.org
L Braiman, A Alt, T Kuroki, M Ohba, A Bak, … - Molecular Endocrinology, 2001 - Endocrine Soc
Certain protein kinase C (PKC) isoforms, in particular PKCs ßII, , and , are
activated by insulin stimulation. In primary cultures of skeletal muscle, PKCs
ßII and , but not PKC , are activated via a phosphatidylinositol 3-kinase ...
Cited by 38 - Related articles - BL Direct - All 7 versions

Protein Kinase C {{delta}}-mediated Phosphorylation of {{alpha}} 6 {beta} 4 Is Associated …

- aacrjournals.org
A Alt, M Ohba, L Li, M Gartsbein, A Belanger, … - Cancer Research, 2001 - AACR
In mammalian epidermis, expression of the 6ß4 integrin is restricted to the
hemidesmosome complexes, which connect the proliferative basal cell layer with
the underlying basement membrane. Keratinocyte differentiation is ...
Cited by 40 - Related articles - BL Direct - All 3 versions


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