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Scholar Results 1 - 10 of about 101 related to Wojtaszewski: Regulation of Glycogen Synthase Kinase-3 in Human Skeletal Muscle. (0.12 sec) 

Regulation of Glycogen Synthase Kinase-3 in Human Skeletal Muscle

- diabetesjournals.org
JFP Wojtaszewski, P Nielsen, B Kiens, EA … - Diabetes, 2001 - Am Diabetes Assoc
Studies of skeletal muscle from rodents performed both in vivo and in vitro
suggest a regulatory role of glycogen synthase kinase (GSK) 3 in glycogen
synthase (GS) activation in response to insulin. Recently, ...
Cited by 54 - Related articles - BL Direct - All 4 versions

Insulin and exercise decrease glycogen synthase kinase-3 activity by different mechanisms …


JF Markuns, JFP Wojtaszewski, LJ Goodyear - Journal of Biological Chemistry, 1999 - ASBMB
Glycogen synthase activity is increased in response to insulin and exercise in
skeletal muscle. Part of the mechanism by which insulin stimulates glycogen
synthesis may involve phosphorylation and activation of Akt, serine ...
Cited by 113 - Related articles - BL Direct - All 6 versions

Exercise regulates Akt and glycogen synthase kinase-3 activities in human skeletal muscle


K Sakamoto, DEW Arnolds, I Ekberg, A … - Biochemical and Biophysical Research …, 2004 - Elsevier
Activation of Akt and deactivation of GSK3 are critical signals regulating a
number of cellular processes in multiple systems. Whether physical exercise
alters Akt and GSK3 activity in human skeletal muscle is controversial. β- ...
Cited by 43 - Related articles - All 4 versions

Exercise and insulin cause GLUT-4 translocation in human skeletal muscle

- physiology.org
A Thorell, MF Hirshman, J Nygren, L Jorfeldt … - American Journal of Physiology- Endocrinology And …, 1999 - Am Physiological Soc
Studies in rodents have established that GLUT-4 translocation is the major
mechanism by which insulin and exercise increase glucose uptake in skeletal
muscle. In contrast, much less is known about the translocation phenomenon ...
Cited by 84 - Related articles - BL Direct - All 5 versions

Akt signaling in skeletal muscle: regulation by exercise and passive stretch

- physiology.org
K Sakamoto, WG Aschenbach, MF Hirshman, … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc
Akt/protein kinase B is a serine/threonine kinase that has emerged as a critical
signaling component for mediating numerous cellular responses. Contractile
activity has recently been demonstrated to stimulate Akt signaling in ...
Cited by 78 - Related articles - BL Direct - All 4 versions

Exercise does not alter subcellular localization, but increases phosphorylation of insulin- …

- physiology.org
C Wilson, M Hargreaves, KF Howlett - American Journal of Physiology- Endocrinology And …, 2006 - Am Physiological Soc
The subcellular localization of insulin signaling proteins is altered by various
stimuli such as insulin, insulin-like growth factor I, and oxidative stress and
is thought to be an important mechanism that can influence intracellular ...
Cited by 15 - Related articles - BL Direct - All 5 versions

The muscle-specific protein phosphatase PP1G/RGL (GM) is essential for activation of …

- jbc.org
WG Aschenbach, Y Suzuki, K Breeden, C Prats … - Journal of Biological Chemistry, 2001 - ASBMB
In skeletal muscle both insulin and contractile activity are physiological
stimuli for glycogen synthesis, which is thought to result in part from the
dephosphorylation and activation of glycogen synthase (GS). PP1G/R GL (G M ...
Cited by 65 - Related articles - BL Direct - All 3 versions

Insulin signaling after exercise in insulin receptor substrate-2-deficient mice

- diabetesjournals.org
KF Howlett, K Sakamoto, MF Hirshman, WG … - Diabetes, 2002 - Am Diabetes Assoc
The period immediately after exercise is characterized by enhanced insulin
action in skeletal muscle, and on the molecular level, by a marked increase in
insulin-stimulated, phosphotyrosine-associated phosphatidylinositol (PI) 3- ...
Cited by 36 - Related articles - BL Direct - All 6 versions

Contraction regulation of Akt in rat skeletal muscle

- jbc.org
K Sakamoto, MF Hirshman, WG Aschenbach, … - Journal of Biological Chemistry, 2002 - ASBMB
The protein serine/threonine kinase Akt/protein kinase B has been recognized as
a critical signaling mediator for multiple cell systems. The function of Akt in
skeletal muscle is not well understood, and whether contractile activity ...
Cited by 108 - Related articles - BL Direct - All 5 versions

Contraction-stimulated muscle glucose transport and GLUT-4 surface content are …

- physiology.org
W Derave, S Lund, GD Holman, J … - American Journal of Physiology- Endocrinology And …, 1999 - Am Physiological Soc
The influence of muscle glycogen content on basal and contraction-induced
glucose transport and cell surface GLUT-4 content was studied in rat skeletal
muscle. Wistar rats were preconditioned by a combination of swimming ...
Cited by 56 - Related articles - All 5 versions


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