- ►diabetesjournals.org RD Molano, T Berney, H Li, P Cattan, A Pileggi … - Diabetes, 2001 - Am Diabetes Assoc Allorejection and recurrence of autoimmunity are the major barriers to
transplantation of islets of Langerhans for the cure of type 1 diabetes in
humans. CD40-CD154 (CD40 ligand) interaction blockade by the use of ... Cited by 76 - Related articles - BL Direct - All 4 versions
TG Markees, DV Serreze, NE Phillips, CH … - DIABETES-NEW YORK-, 1999 - Am Diabetes Assoc A protocol consisting of a single donor-specific trans- fusion (DST) plus a
brief course of anti-CD154 mono- clonal antibody (anti-CD40 ligand mAb) induces
per- manent islet allograft survival in chemically diabetic mice, but its ... Cited by 79 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org T Pearson, TG Markees, LS Wicker, DV … - Diabetes, 2003 - Am Diabetes Assoc The loss of self-tolerance leading to autoimmune type 1 diabetes in the NOD
mouse model involves at least 19 genetic loci. In addition to their genetic
defects in self-tolerance, NOD mice resist peripheral transplantation ... Cited by 21 - Related articles - BL Direct - All 6 versions
KL Kover, Z Geng, DM Hess, CD Benjamin, … - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc Islet transplantation for the treatment of autoimmune diabetes is more difficult
because of the additional bar- rier presented by the autoimmunity. We tested the
abil- ity of hamster anti-rat CD154 to prevent recurrence of diabetes in ... Cited by 21 - Related articles - BL Direct - All 4 versions
RD Molano, A Pileggi, T Berney, R Poggioli, E … - Diabetes, 2003 - Am Diabetes Assoc Clinical islet transplantation is a successful procedure that can improve the
quality of life in recipients with diabetes. A drawback of the procedure is the
need for chronic administration of immunosuppressive drugs that, among ... Cited by 31 - Related articles - BL Direct - All 4 versions
B Balasa, T Krahl, G Patstone, J Lee, R Tisch … - The Journal of Immunology, 1997 - Am Assoc Immnol Page 1. CD40 Ligand-CD40 Interactions Are Necessary for the Initiation of
lnsulitis and Diabetes in Nonobese Diabetic Mice' Balaji ... Cited by 160 - Related articles - BL Direct - All 3 versions
RD Molano, T Berney, A Pileggi, C Ricordi, L … - Transplantation proceedings, 2001 - Elsevier Spontaneously diabetic NOD mice were transplanted with 650 islet equivalents
isolated from C57BL/6 mice under the kidney capsule and assigned to one of five
different groups according to the treatment they received. Group 1 was ... Cited by 11 - Related articles - BL Direct - All 4 versions
L Makhlouf, K Kishimoto, RN Smith, R Abdi, … - Diabetes, 2002 - Am Diabetes Assoc Although it has often been assumed that transplanted allogeneic islets can be
destroyed by recurrent autoimmunity in recipients with type 1 diabetes,
definitive evidence is lacking and the settings in which this may occur ... Cited by 40 - Related articles - BL Direct - All 5 versions
- ►pnas.org NS Kenyon, M Chatzipetrou, M Masetti, A … - Proceedings of the National Academy of Sciences, 1999 - National Acad Sciences Reported effects of anti-CD154 treatment on autoimmunity, alloreactivity, and
inflammatory events mediated by macrophages and endothelial cells indicated that
it might be an ideal agent for the prevention of intrahepatic islet ... Cited by 318 - Related articles - BL Direct - All 8 versions
