- ►diabetesjournals.org T Masaki, H Yoshimatsu, S Chiba, T Watanabe … - Diabetes, 2001 - Am Diabetes Assoc Leptin resistance has recently been confirmed not only in animal obese models
but in human obesity. Evidence is rapidly emerging that suggests that activation
of histamine signaling in the hypothalamus may have substantial ... Cited by 60 - Related articles - BL Direct - All 7 versions
H Yoshimatsu, E Itateyama, S Kondou, D … - DIABETES-NEW YORK-, 1999 - Am Diabetes Assoc Leptin, an ob gene product, has been shown to sup- press food intake by
regulating hypothalamic neuro- modulators. The present study was designed to
exam- ine the involvement of brain histamine in leptin- induced feeding ... Cited by 81 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org T Masaki, H Yoshimatsu, S Chiba, T Watanabe … - Diabetes, 2001 - Am Diabetes Assoc Histamine neurons are widely distributed in the brain and suppress food intake
through the histamine H 1 receptor (H 1 -R) in the hypothalamus. To examine the
role of neuronal histamine in leptin signaling pathways, we investigated ... Cited by 72 - Related articles - BL Direct - All 6 versions
- ►ebmonline.org K Tsuda, H Yoshimatsu, A Niijima, S Chiba, T … - Experimental Biology and Medicine, 2002 - SEBM The contribution of hypothalamic histamine neurons to the central regulation of
peripheral lipid metabolism was investigated in rats using in vivo microdialysis
system. A bolus infusion of L-histamine at doses of 10–10 3 nmol/rat into ... Cited by 36 - Related articles - BL Direct - All 4 versions
T Sakata, H Yoshimatsu, M Kurokawa - Nutrition, 1997 - Elsevier In a series of studies on histaminergic functions in the hypothalamus, probes to
manipulate activities of histaminergic neuron systems were applied to assess its
physiologic and pathophysiologic implications using non-obese normal and ... Cited by 104 - Related articles - BL Direct - All 8 versions
- ►ebmonline.org H Yoshimatsu, S Chiba, D Tajima, Y Akehi, T … - Experimental Biology and Medicine, 2002 - SEBM Hypothalamic neuronal histamine has been shown to regulate feeding behavior and
energy metabolism as a target of leptin action in the brain. The present study
aimed to examine the involvement of L-histidine, a precursor of neuronal ... Cited by 29 - Related articles - BL Direct - All 5 versions
T Masaki, S Chiba, T Yasuda, H Noguchi, T … - Diabetes, 2004 - Am Diabetes Assoc Histamine H 1 receptors (H 1 -Rs) are found in peripheral tissues and in regions
of the hypothalamus that are concerned with regulating body composition. In the
present study, we investigated the detailed mechanisms of histamine H 1 -Rs ... Cited by 50 - Related articles - BL Direct - All 6 versions
H Yoshimatsu, H Machidori, T Doi, M … - Physiology & behavior, 1993 - Elsevier Histaminergic functions in the hypothalamus of Zucker obese rats were
investigated. Blockade of postsynaptic H 1 -receptor after infusion of
chlorpheniramine into the third cerebroventricle (ICV) failed to affect ... Cited by 20 - Related articles - BL Direct - All 3 versions
- ►endojournals.org T Masaki, S Chiba, G Yoshimichi, T Yasuda, … - Endocrinology, 2003 - Endocrine Soc LEPTIN IS A CRUCIAL factor in the regulation of energy intake and expenditure
(1, 2, 3). There is increasing evidence that the effects of leptin are governed
by a number of hypothalamic mediators including orexigenic substances such ... Cited by 19 - Related articles - BL Direct - All 5 versions
T Sakata, K Ookuma, K Fukagawa, K Fujimoto, … - Brain research, 1988 - ncbi.nlm.nih.gov All H1-, but no H2-antagonists infused into the rat third cerebroventricle,
induced feeding during the early light, but not during the early dark,
reflecting a concentration of hypothalamic histamine. Bilateral ... Cited by 65 - Related articles - All 2 versions
