- ►flexcellint.com [PDF] I Suzuma, Y Hata, A Clermont, F Pokras, SL Rook, K … - Diabetes, 2001 - Am Diabetes Assoc Systemic hypertension exacerbates diabetic retinopathy and other coexisting ocular disorders
through mechanisms that remain largely unknown. Increased vascular permeability and intraocular
neovascularization characterize these conditions and are complications primarily ... Cited by 46 - Related articles - BL Direct - All 6 versions
I Suzuma, K Suzuma, K Ueki, Y Hata, EP Feener, … - Journal of Biological …, 2002 - ASBMB Stretch-induced expression of vascular endothelial growth factor (VEGF) is thought to be important
in mediating the exacerbation of diabetic retinopathy by systemic hypertension. However, the
mechanisms underlying stretch-induced VEGF expression are not fully understood. We ... Cited by 46 - Related articles - BL Direct - All 3 versions
- ►iovs.org Y Seko, Y Seko, H Fujikura, J Pang, T Tokoro, H … - … ophthalmology & visual …, 1999 - ARVO METHODS. A pulsatile stretch device was used in vitro. RPE cells of the second passage were
seeded onto flexible-bottomed culture plates; then, at subconfluent culture, the plates were subjected
to pulsatile stretch. Culture plates prepared in the same way but not subjected to stretch ... Cited by 30 - Related articles - BL Direct - All 4 versions
JCS Yam, AKH Kwok - HONG KONG MEDICAL JOURNAL, 2007 - milray.org Diabetic retinopathy (DR) is the commonest microvascular complication of diabetes, and remains
one of the leading causes of blindness worldwide.1 During the first two decades of disease, nearly
all patients with type 1 diabetes and over 60% with type 2 diabetes develop retinopathy. ... Cited by 22 - Related articles - View as HTML - BL Direct - All 3 versions
- ►ahajournals.org CJ Moravski, DJ Kelly, ME Cooper, RE Gilbert, JF … - Hypertension, 2000 - Am Heart Assoc Both angiotensin II and vascular endothelial growth factor are angiogenic agents that have recently
been implicated in the pathogenesis of proliferative diabetic retinopathy. In this study, retinal
neovascularization was examined in a model of retinopathy of prematurity with the use of ... Cited by 110 - Related articles - BL Direct - All 4 versions
TH Wheeler-Schilling, K Kohler, M … - European Journal of …, 1999 - interscience.wiley.com In addition to its function as a peripheral hormone, angiotensin II (AngII) has been shown to act
as a neuromodulator in various brain regions. AngII effects are mediated by two major AngII receptor
subtypes, AT 1 and AT 2 , and different AT 1 receptor isoforms AT 1A and AT 1B are ... Cited by 30 - Related articles - BL Direct - All 5 versions
- ►iovs.org M Lonchampt, L Pennel, J Duhault - Investigative ophthalmology & visual science, 2001 - ARVO METHODS. A previously described model was used in which oxygen cycling (5 days hyperoxia
and 5 days hypoxia) induced retinal alterations in newborn mice. An angiotensin-converting
enzyme inhibitor (perindopril), or angiotensin receptor antagonists AT1 (losartan) or AT2 ( ... Cited by 43 - Related articles - BL Direct - All 6 versions
- ►iovs.org [PDF] JL Berka, AJ Stubbs, DZ Wang, R DiNicolantonio, D … - … ophthalmology & visual …, 1995 - ARVO Purpose. An ocular renin-angiotensin system has been implicated in the proliferation of retinal
blood vessels and blindness in diabetes mellitus. Its cellular basis has not been established.
The objective was to identify sites of renin synthesis, secretion, and processing in eyes ... Cited by 67 - Related articles - BL Direct - All 3 versions
WM Wan Nazaimoon, R Letchuman, N Noraini, AR … - Diabetes research and …, 1999 - Elsevier This cross-sectional study looked at the prevalence of microalbuminuria and retinopathy in a
cohort of 926 young, Type 1 and Type 2 diabetes mellitus (DM) patients, and determined the
factors which were associated with these microvascular complications. The prevalence of ... Cited by 28 - Related articles - All 8 versions
CB Engler, HH Parving, ER Mathiesen, M Larsen … - Acta …, 1991 - interscience.wiley.com Abstract. We assessed the acute effect of ACE-inhibition (captopril) on blood-retina barrier
(BRB) permeability in 10 hypertensive insulin-dependent diabetic patients with background retinopathy
in a double-masked placebo controlled cross-over study. All patients underwent ... Cited by 10 - Related articles - All 2 versions
