- ►ufl.edu [PDF] T Flotte, A Agarwal, J Wang, S Song, ES Fenjves, L … - Diabetes, 2001 - Am Diabetes Assoc The ability to transfer immunoregulatory, cytoprotective, or antiapoptotic genes into pancreatic
islet cells may allow enhanced posttransplantation survival of islet allografts and inhibition of
recurrent autoimmune destruction of these cells in type 1 diabetes. However, transient ... Cited by 65 - Related articles - BL Direct - All 5 versions
M Kapturczak, S Zolotukhin, J Cross, A Pileggi, … - Molecular …, 2002 - immunology.ufl.edu Matthias Kapturczak,1 Sergei Zolotukhin,2,3 Jeff Cross,4 Antonello Pileggi,5 R. Damaris
Molano,5 Marda Jorgensen,4 Barry Byrne,2,3,6 Terence R. Flotte,2,3,6 Tamir Ellis,4 Luca
Inverardi,5 Camillo Ricordi,5 Harry Nick,7 Mark Atkinson,4 and Anupam Agarwal1,* Cited by 23 - Related articles - BL Direct - All 6 versions
N Giannoukakis, Z Mi, A Gambotto, A Eramo, C Ricordi, … - Gene therapy, 1999 - ncbi.nlm.nih.gov The transfer of genes encoding immunomodulatory proteins to islets can be used to improve
islet function, block apoptosis, and inhibit rejection following transplantation. Adenoviral vectors
have been shown to infect intact human islets, but the immunogenicity and transient gene ... Cited by 49 - Related articles - BL Direct - All 3 versions
Q Ju, D Edelstein, MD Brendel, D Brandhorst, H … - Diabetologia, 1998 - Springer Amajorlong-termgoalofdiabetesresearchistore-es- tablish normal glucose homeostasis in
insulin-defi- cient patients by transplantation of insulin-producing beta cells [1]. The major unsolved
problems of human beta-cell transplantation are overcoming allorejec- tion, preventing ... Cited by 46 - Related articles - BL Direct - All 3 versions
SA Loiler, TJ Conlon, S Song, Q Tang, KH Warrington, … - Gene Therapy, 2003 - nature.com Human pancreatic islet cells and hepatocytes represent the two most likely target cells for genetic
therapy of type I diabetes. However, limits to the efficiency of rAAV serotype 2 (rAAV2)-mediated
gene transfer have been reported for both of these cell targets. Here we report that ... Cited by 65 - Related articles - BL Direct - All 3 versions
JL Contreras, G Bilbao, CA Smyth, XL Jiang, DE … - Transplantation, 2001 - journals.lww.com Skip Navigation Links Home > April 27, 2001 - Volume 71 - Issue 8 > CYTOPROTECTION OF
PANCREATIC ISLETS BEFORE AND SOON AFTER TR... ... Contreras, Juan L.; Bilbao,
Guadalupe; Smyth, Cheryl A.; Jiang, Xiao L.; Eckhoff, Devin E.; Jenkins, Stacie M.; ... Cited by 62 - Related articles - BL Direct - All 5 versions
J Saldeen, DT Curiel, DL Eizirik, A Andersson, E … - Diabetes, 1996 - Am Diabetes Assoc The establishment of gene delivery systems that result in efficient transfection of the pancreatic
beta-cells may generate an important tool for the study of IDDM and may also represent one
critical step toward a clinical application of gene transfer for the prevention or early ... Cited by 50 - Related articles - BL Direct - All 5 versions
KK Rehman, Z Wang, R Bottino, AN Balamurugan, M … - Gene Therapy, 2005 - nature.com Transplantation of allogeneic pancreatic islets is an effective approach to treat type 1
diabetes. To bypass the need for systemic administration of immunosuppression drugs following
transplantation, approaches to genetically modify allogeneic islets to express anti- ... Cited by 17 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] G Leibowitz, GM Beattie, T Kafri, V Cirulli, AD Lopez, A … - Diabetes, 1999 - Am Diabetes Assoc We have studied the factors that influence the eff i- ciency of infection of human fetal and adult
pancreatic endocrine cells with adenovirus, murine retrovirus, and lentivirus vectors all expressing
the green fluorescent protein (Ad-GFP, MLV- GFP, and Lenti-GFP, respec- tively). ... Cited by 88 - Related articles - BL Direct - All 4 versions
