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Scholar Results 1 - 10 of about 101 related to Shiota: Glucokinase gene locus transgenic mice are resistant to the development of obesity-induce.... (0.13 sec) 

Glucokinase gene locus transgenic mice are resistant to the development of obesity-induced …

- diabetesjournals.org
M Shiota, C Postic, Y Fujimoto, TL Jetton, K … - Diabetes, 2001 - Am Diabetes Assoc
Transgenic mice that overexpress the entire glucokinase (GK) gene locus have
been previously shown to be mildly hypoglycemic and to have improved tolerance
to glucose. To determine whether increased GK might also prevent or ...
Cited by 59 - Related articles - BL Direct - All 7 versions

Phenotypic correction of diabetic mice by adenovirus-mediated glucokinase expression


UJ Desai, ED Slosberg, BR Boettcher, SL … - Diabetes, 2001 - Am Diabetes Assoc
Hyperglycemia of diabetes is caused in part by perturbation of hepatic glucose
metabolism. Hepatic glucokinase (GK) is an important regulator of glucose
storage and disposal in the liver. GK levels are lowered in patients with ...
Cited by 63 - Related articles - BL Direct - All 5 versions

[PDF] Correction of diabetic alterations by glucokinase


T Ferre, A Pujol, E Riu, F Bosch, A Valera - Proc Natl Acad Sci USA, 1996 - National Acad Sciences
Page 1. Proc. Natl. Acad. Sci. USA Vol. 93, pp. 7225-7230, July 1996 Medical
Sciences Correction of diabetic alterations by glucokinase ...
Cited by 119 - Related articles - BL Direct - All 10 versions

Administration of D-glucosamine into the third cerebroventricle induced feeding …


K Fujimoto, T Sakata, K Arase, K Kurata, Y … - Life sciences, 1985 - ncbi.nlm.nih.gov
D-glucosamine, 2-amino-2-deoxy-D-glucose, is known to be an endogenous glucose
analogue and to antagonize glucose uptake and metabolism. The present
experiments were aimed to clarify effects of glucosamine and related ...
Cited by 28 - Related articles - All 2 versions

Glucokinase overexpression restores glucose utilization and storage in cultured hepatocytes …

- jbc.org
J Seoane, A Barbera, S Telemaque-Potts, CB … - Journal of Biological Chemistry, 1999 - ASBMB
Zucker diabetic fatty rats develop type 2 diabetes concomitantly with peripheral
insulin resistance. Hepatocytes from these rats and their control lean
counterparts have been cultured, and a number of key parameters of glucose ...
Cited by 38 - Related articles - BL Direct - All 5 versions

[PDF] Potassium channel dysfunction in hypothalamic glucose-receptive neurones of obese Zucker …


ICM Rowe, PR Boden, MLJ Ashford - Journal of Physiology, 1996 - Physiological Soc
Page 1. Journal of Physiology (1996), 497.2, pp.365-377 Potassium channel dysfunction
in hypothalamic glucose-receptive neurones of obese Zucker rats ...
Cited by 29 - Related articles - BL Direct - All 7 versions

In vivo and in vitro regulation of [3H] glyburide binding to brain sulfonylurea receptors in …


BE Levin, AA Dunn-Meynell - Brain research, 1997 - Elsevier
Select brain neurons increase their firing rate when ambient glucose levels
rise, possibly via a neuronal ATP-sensitive K + (K ATP ) channel and its
associated sulfonylurea receptor (SUR). We used receptor autoradiographic ...
Cited by 35 - Related articles - All 5 versions

D-glucose suppression of eating after intra-third ventricle infusion in rat


K Kurata, K Fujimoto, T Sakata, H Etou, K … - Physiology & behavior, 1986 - Elsevier
To clarify the hypophagic action of D-glucose, meal size, postprandial intermeal
interval and eating rate were analyzed after infusion of glucose into the third
cerebroventricle. The effects of glucose structure modification on feeding ...
Cited by 39 - Related articles - All 3 versions

Liver glucokinase: decreased activity in patients with type II diabetes.


JF Caro, S Triester, VK Patel, EB Tapscott, … - Hormone and metabolic research. Hormon-und …, 1995 - ncbi.nlm.nih.gov
Because of the demonstration of a genetic linkage between glucokinase and Type
II diabetes, and the central role of glucokinase on glucose metabolism, we
studied glucokinase activity in the liver of patients with and without Type ...
Cited by 76 - Related articles - BL Direct - All 3 versions

Differential effects of diet and obesity on high and low affinity sulfonylurea binding sites in the …


BE Levin, KL Brown, AA Dunn-Meynell - Brain research, 1996 - Elsevier
The brain contains neurons which alter their firing rates when ambient glucose
concentrations change. An ATP-sensitive K + (K atp ) channel on these neurons
closes and increases cell firing when ATP is produced by intracellular ...
Cited by 41 - Related articles - BL Direct - All 5 versions


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