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Scholar Results 1 - 10 of about 101 related to Michaud: Direct regulatory effect of fatty acids on macrophage lipoprotein lipase. (0.20 sec) 

Direct regulatory effect of fatty acids on macrophage lipoprotein lipase

- diabetesjournals.org
SÉ Michaud, G Renier - Diabetes, 2001 - Am Diabetes Assoc
Atherosclerosis is a major complication of type 2 diabetes. The pathogenesis of this complication
is poorly understood, but it clearly involves production in the vascular wall of macrophage
(Mo) lipoprotein lipase (LPL). Mo LPL is increased in human diabetes. Peripheral factors ...
Cited by 55 - Related articles - BL Direct - All 5 versions

Stimulatory effect of glucose on macrophage lipoprotein lipase expression and …

- diabetesjournals.org [PDF] 
MR Sartippour, A Lambert, M Laframboise, P St- … - Diabetes, 1998 - Am Diabetes Assoc
Cardiovascular diseases are the leading cause of mor- bidity and mortality in diabetes. Lipoprotein
lipase (LPL), a major secretory product of macrophages, has been suggested to play a key role
in the development of atherosclerosis. In the present study, we evaluated the e ffect of ...
Cited by 38 - Related articles - BL Direct - All 5 versions

[PDF] Upregulation of macrophage lipoprotein lipase in patients with type 2 diabetes


MR Sartippour, G Renier - Diabetes, 2000 - Am Diabetes Assoc
Atherosclerosis is the major complication of diabetes. Accumulating evidence indicates that lipoprotein
lipase (LPL) produced by macrophages in the vascular wall may favor the development of atherosclerosis
by promoting lipid accumulation within the lesion. We pre- viously demonstrated that high ...
Cited by 40 - Related articles - BL Direct - All 3 versions

Proliferative effect of lipoprotein lipase on human vascular smooth muscle cells

- ahajournals.org
JC Mamputu, L Levesque, G Renier - Arteriosclerosis, thrombosis, and …, 2000 - Am Heart Assoc
Abstract—Vascular smooth muscle cell (VSMC) proliferation is a key event in the development
and progression of atherosclerotic lesions. Accumulating evidence suggests that lipoprotein
lipase (LPL) produced in the vascular wall may exert proatherogenic effects. The aim of ...
Cited by 27 - Related articles - BL Direct - All 7 versions

Role of oxidant injury on macrophage lipoprotein lipase (LPL) production and …

- jlr.org [PDF] 
G Renier, AC Desfaits, A Lambert, R Mikhail - The Journal of Lipid Research, 1996 - ASBMB
Abstract We investigated, in the present study, the role of reactive oxygen intermediates
(ROI) in the control of macro- phage lipoprotein lipase (LPL) secretion. Exposure of murine macrophages
to increasing concentrations of hydrogen per- oxide (H202) resulted in enhanced basal ...
Cited by 15 - Related articles - BL Direct - All 3 versions

Differential regulation of macrophage peroxisome proliferator-activated receptor …

- ahajournals.org
MR Sartippour, G Renier - Arteriosclerosis, thrombosis, and vascular …, 2000 - Am Heart Assoc
Abstract—Peroxisome proliferator–activated receptors (PPARs) are implicated in several metabolic
disorders with altered glucose and lipid metabolism, including atherosclerosis and diabetes.
In the present study, we evaluated the in vitro and ex vivo effects of high glucose ...
Cited by 47 - Related articles - BL Direct - All 6 versions

Homocysteine induces protein kinase C activation and stimulates c-Fos and …

- diabetesjournals.org
MC Beauchamp, G Renier - Diabetes, 2002 - Am Diabetes Assoc
Hyperhomocysteinemia is an independent risk factor for cardiovascular disease in human
diabetes. Among the multiple factors that may account for the atherogenicity of homocysteine
(Hcys) in patients with diabetes, macrophage (Mo) lipoprotein lipase (LPL) has unique ...
Cited by 28 - Related articles - BL Direct - All 4 versions

Sp1 and Sp3 transactivate the human lipoprotein lipase gene promoter through …

- jlr.org
WS Yang, SS Deeb - The Journal of Lipid Research, 1998 - ASBMB
Lipoprotein lipase (LPL) is a key enzyme in lipoprotein and energy metabolism and,
therefore, regulation of its expression could have an important bearing on these processes. We
have identified an evolutionarily conserved 5'-CCTCCCCCC-3' motif (from -91 to -83, CT ...
Cited by 33 - Related articles - BL Direct - All 3 versions

Induction of tumor necrosis factor alpha gene expression by lipoprotein lipase

- jlr.org [PDF] 
G Renier, E Skamene, JB DeSanctis, D Radzioch - The Journal of Lipid …, 1994 - ASBMB
Abstract In view of the suppressive effect of tumor necrosis factor a (TNFa) on lipoprotein lipase
(LPL) and of the potential proatherogenic effects of these two macrophage secretory
products, we have tested the possibility that LPL could modulate the production of TNFa. ...
Cited by 36 - Related articles - BL Direct - All 3 versions

Lipoprotein lipase, a key role in atherosclerosis?


JR Mead, A Cryer, DP Ramji - FEBS letters, 1999 - Elsevier
Lipoprotein lipase (LPL) plays a central role in lipid metabolism and transport by catalysing the
hydrolysis of triacylglycerol-rich lipoproteins. The importance of LPL expressed by the adipose
tissue and muscles in the provision of non-esterified fatty acids and 2-monoacylglycerol ...
Cited by 61 - Related articles - All 5 versions


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