M Tschöp, C Weyer, PA Tataranni, V Devanarayan, E … - Diabetes, 2001 - Am Diabetes Assoc Ghrelin is a novel endogenous natural ligand for the growth hormone (GH) secretagogue receptor
that has recently been isolated from the rat stomach. Ghrelin administration stimulates GH secretion
but also causes weight gain by increasing food intake and reducing fat utilization in ... Cited by 894 - Related articles - BL Direct - All 5 versions
- ►endojournals.org T Shiiya, M Nakazato, M Mizuta, Y Date, MS … - Journal of Clinical …, 2002 - Endocrine Soc Plasma ghrelin concentrations in patients with simple obesity and anorexia nervosa were lower
and higher, respectively, than those of healthy subjects with normal body weight. Among those
with type 2 diabetes mellitus, obese patients had lower and lean patients higher fasting ... Cited by 643 - Related articles - BL Direct - All 5 versions
DE Cummings, JQ Purnell, RS Frayo, K Schmidova, BE … - Diabetes, 2001 - Am Diabetes Assoc The recently discovered orexigenic peptide ghrelin is produced primarily by the stomach and
circulates in blood at levels that increase during prolonged fasting in rats. When administered
to rodents at supraphysiological doses, ghrelin activates hypothalamic neuropeptide Y/ ... Cited by 1118 - Related articles - BL Direct - All 5 versions
M Tschöp, DL Smiley, ML Heiman - Nature, 2000 - nature.com The discovery of the peptide hormone ghrelin, an endogenous ligand for the growth hormone
secretagogue (GHS) receptor 1, 2 , yielded the surprising result 3 that the principal site of ghrelin
synthesis is the stomach and not the hypothalamus. Although ghrelin is likely to regulate ... Cited by 1693 - Related articles - BL Direct - All 5 versions
B Otto, U Cuntz, E Fruehauf, R Wawarta, C … - European Journal of …, 2001 - eje.org OBJECTIVE: Ghrelin is a new gastric hormone that has been identified as an endogenous ligand
for the growth hormone (GH) secretagogue receptor subtype 1a (GHS-R1a). Ghrelin administration
however not only stimulates GH secretion but also induces adiposity in rodents by ... Cited by 344 - Related articles - BL Direct - All 9 versions
DE Cummings, DS Weigle, RS Frayo, PA … - New England Journal …, 2002 - content.nejm.org Results Plasma ghrelin levels rose sharply shortly before and fell shortly after every meal. A
diet-induced weight loss of 17 percent of initial body weight was associated with a 24 percent
increase in the area under the curve for the 24-hour ghrelin profile (P=0.006). In contrast, ... Cited by 1023 - Related articles - BL Direct - All 8 versions
- ►endojournals.org H Ariyasu, K Takaya, T Tagami, Y Ogawa, K … - Journal of Clinical …, 2001 - Endocrine Soc Ghrelin, an endogenous ligand for the GH secretagogue receptor, was isolated from rat stomach
and is involved in a novel system for regulating GH release. Although previous studies in rodents
suggest that ghrelin is also involved in energy homeostasis and that ghrelin secretion is ... Cited by 561 - Related articles - BL Direct - All 4 versions
M Nakazato, N Murakami, Y Date, M Kojima, H Matsuo, … - Nature, 2001 - nature.com Ghrelin is an acylated peptide that stimulates the release of growth hormone from the pituitary
1 . Ghrelin-producing neurons are located in the hypothalamus, whereas ghrelin receptors are
expressed in various regions of the brain 2, 3, 4 , which is indicative of central—and as ... Cited by 1384 - Related articles - BL Direct - All 6 versions
M Tschöp, C Weyer, PA Tataranni, V Devanarayan, E … - Diabetes, 2001 - Am Diabetes Assoc Ghrelin is a novel endogenous natural ligand for the growth hormone (GH) secretagogue receptor
that has recently been isolated from the rat stomach. Ghrelin administration stimulates GH secretion
but also causes weight gain by increasing food intake and reducing fat utilization in ... Cited by 7 - Related articles
