- ►diabetesjournals.org R Ritzel, M Schulte, N Pørksen, MS Nauck, … - Diabetes, 2001 - Am Diabetes Assoc The insulinotropic gut hormone glucagon-like peptide (GLP)-1 increases secretory
burst mass and the amplitude of pulsatile insulin secretion in healthy
volunteers without affecting burst frequency. Effects of GLP-1 on secretory ... Cited by 42 - Related articles - BL Direct - All 4 versions
CB Juhl, O Schmitz, S Pincus, JJ Holst, J … - Diabetologia, 2000 - Springer Type II (non-insulin-dependent) diabetes mellitus is among a vast number of
abnormalities characterised by disturbed beta-cell function. This includes
defects in first-phase and second-phase insulin secretion as Cited by 18 - Related articles - BL Direct - All 4 versions
N Pørksen, B Grøfte, B Nyholm, JJ Holst, SM … - Diabetes, 1998 - Am Diabetes Assoc Glucagon-like peptide 1 (GLP-1) is a peptide hormone that is released from the
gut after luminal stimulation. The hormone is a potent insulin secretagogue and
is a potential novel pharmaceutical adjuvant in the treatment of NIDDM. ... Cited by 30 - Related articles - BL Direct - All 5 versions
N Porksen, S Munn, J Steers, JD Veldhuis, PC … - American Journal of Physiology- Endocrinology And …, 1995 - Am Physiological Soc INSULIN, LIKE THE hypothalamopituitary hormones, is secreted in a pulsatile
manner (4, 18). However, in contrast to pituitary hormones, the optimal sampling
intensity, duration, and vascular site for insulin have not been fully ... Cited by 27 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org [PDF] MM Byrne, K Gliem, U Wank, R Arnold, M … - Diabetes, 1998 - Am Diabetes Assoc Impaired glucose tolerance (IGT) and NIDDM are both associated with an impaired
ability of the -cell to sense and respond to small changes in plasma glucose
concentrations. The aim of this study was to establish if glucagon-like ... Cited by 47 - Related articles - BL Direct - All 5 versions
CB Juhl, N Pørksen, SM Pincus, ÅP Hansen, … - Diabetes, 2001 - Am Diabetes Assoc The high-frequency oscillatory pattern of insulin release is disturbed in type 2
diabetes. Although sulfonylurea drugs are widely used for the treatment of this
disease, their effect on insulin release patterns is not well established. ... Cited by 20 - Related articles - BL Direct - All 4 versions
B Willms, K Idowu, JJ Holst, W Creutzfeldt, … - Experimental and clinical endocrinology & diabetes: …, 1998 - ncbi.nlm.nih.gov GLP-1 (7-36 amide) normalizes fasting plasma glucose in NIDDM patients. It was
the aim to study the effect of overnight intravenous GLP-1 (7-36 amide) on the
following 24 h-glucose profiles. Ten NIDDM patients (7 female, 3 male; age ... Cited by 18 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org [PDF] MA Nauck, A Sauerwald, R Ritzel, JJ Holst, … - Diabetes Care, 1998 - Am Diabetes Assoc F rom the Department of Medicine (MAN, AS, RR, WS), Ruhr- U niversity,
Knappschafts-Krankenhaus, Bochum, Germany; and the Department of Medical
Physiology (JJH), Panum-Institute, University of Copen- hagen, Copenhagen, ... Cited by 84 - Related articles - All 6 versions
DS Dupuis, M Perez, S Halazy, FC Colpaert, … - Molecular Brain Research, 1999 - Elsevier The present study reports on G-protein activation by recombinant 5-HT receptors
and by native 5-HT 1A and 5-HT 1B receptors in guinea-pig and rat brain using
agonist-stimulated [ 35 S]GTPγS binding responses mediated by a new 5-HT ... Cited by 8 - Related articles - All 4 versions
- ►physiology.org N Porksen, T Grofte, J Greisen, A Mengel, C … - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc Insulin is secreted as a series of punctuated secretory bursts superimposed on
variable basal insulin release. The contribution of these secretory bursts to
overall insulin secretion has been estimated on the basis of peripheral ... Cited by 15 - Related articles - BL Direct - All 3 versions