JA Douglas, MR Erdos, RM Watanabe, A Braun, CL … - Diabetes, 2001 - Am Diabetes Assoc Recent studies have identified a common proline-to-alanine substitution (Pro12Ala) in the peroxisome
proliferator–activated receptor-γ2 (PPAR-γ2), a nuclear receptor that regulates adipocyte
differentiation and possibly ... Cited by 118 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org H Mori, H Ikegami, Y Kawaguchi, S Seino, N Yokoi, J … - Diabetes, 2001 - Am Diabetes Assoc The allele frequencies for a Pro 12 →Ala substitution in peroxisome proliferator–activated
receptor-γ differ among ethnic groups, and its relationship with diabetes and associated diseases
is controversial. The prevalence of ... Cited by 163 - Related articles - BL Direct - All 5 versions
K Hara, T Okada, K Tobe, K Yasuda, Y Mori, H … - … and biophysical research …, 2000 - Elsevier Peroxisome proliferator-activated receptor γ (PPARγ) has been implicated in adipocyte
differentiation. Recently it was reported that heterozygous deficiency of PPARγ led to the
protection from high-fat ... Cited by 228 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org [PDF] FP Mancini, O Vaccaro, L Sabatino, A Tufano, AA … - Diabetes, 1999 - Am Diabetes Assoc Peroxisome proliferator-activated receptor (PPA R ) - is a major regulator of adipogenesis and
insulin sensi- tivit y. The PPA R - gene generates two isoforms through alternative splicing, PPA R
- 1 and - 2, the latter having an ... Cited by 151 - Related articles - BL Direct - All 6 versions
J Ringel, S Engeli, A Distler, AM Sharma - Biochemical and Biophysical …, 1999 - Elsevier Peroxisome proliferator activated receptor-gamma (PPARγ) is a nuclear receptor that regulates
adipocyte differentiation and possibly lipid metabolism and insulin sensitivity. Therefore,PPARγis
a promising candidate gene for ... Cited by 118 - Related articles - BL Direct - All 5 versions
A Meirhaeghe, L Fajas, N Helbecque, D … - International journal of …, 2000 - ncbi.nlm.nih.gov 1: Int J Obes Relat Metab Disord. 2000 Feb;24(2):195-9. Impact of the Peroxisome Proliferator Activated
Receptor gamma2 Pro12Ala polymorphism on adiposity, lipids and non-insulin-dependent diabetes mellitus.
Meirhaeghe A, Fajas L, Helbecque N, Cottel D, Auwerx J, Deeb SS, Amouyel P. ... Cited by 134 - Related articles - BL Direct - All 3 versions
- ►endojournals.org EY Oh, KM Min, JH Chung, YK Min, MS Lee, … - Journal of Clinical …, 2000 - Endocrine Soc Peroxisome proliferator-activated receptors (PPARs) are a nuclear hormone receptor superfamily of
ligand-activated transcription factors, and the PPAR subtype regulates adipocyte differentiation,
lipid metabolism, and insulin ... Cited by 74 - Related articles - BL Direct - All 5 versions
K Clement, S Hercberg, B Passinge, P Galan, M … - International journal of …, 2000 - cat.inist.fr OBJECTIVE: Peroxisome-proliferator-activated receptors y(PPAR y), is a key regulator of adipocyte
differentiation and energy balance. Two naturally occurring mutations in the PPAR γ gene, Pro 115
Gln and Pro 12 Ala, have recently ... Cited by 100 - Related articles - BL Direct - All 2 versions
BA Beamer, CJ Yen, RE Andersen, D Muller, … - DIABETES-NEW …, 1998 - Am Diabetes Assoc T he nuclear receptor, peroxisome proliferator- act i- vated receptor- ( P PA R - ), is an important
regula- tor of adipocyte differentiation and a modulator of intracellular insulin-signaling events
(1). PPA R - mRNA expression in ... Cited by 210 - Related articles - BL Direct - All 5 versions
- ►endojournals.org RA Hegele, H Cao, SB Harris, B Zinman, AJG … - Journal of Clinical …, 2000 - Endocrine Soc Among the Oji-Cree of northern Ontario, we previously identified a novel variant in the HNF1A gene,
namely G319S, that was strongly associated with type 2 diabetes. However, the majority of subjects
with diabetes did not have the ... Cited by 69 - Related articles - BL Direct - All 6 versions
