PA Tataranni, L Baier, C Jenkinson, I Harper, A Del … - Diabetes, 2001 - Am Diabetes Assoc Brain dopaminergic pathways play a major role in the control of movement. Absence of the murine
dopamine D2 receptor gene (drd2) produces bradykinesia and hypothermia. A Ser311Cys mutation
of the human DRD2 produces a marked functional impairment of the receptor and is ... Cited by 28 - Related articles - BL Direct - All 4 versions
MR Spitz, MA Detry, P Pillow, Y Hu, CI Amos, WK Hong … - Nutrition Research, 2000 - Elsevier The mesocorticolimbic dopaminergic reward pathways have a role in the neuromodulation of
appetite. There are data supporting a role of allelic variants of the D2 dopamine receptor
(DRD2) gene and the number of receptor binding sites in vulnerability to substance ... Cited by 24 - Related articles - BL Direct - All 6 versions
CP Jenkinson, R Hanson, K Cray, C Wiedrich, WC … - International journal of …, 2000 - cat.inist.fr OBJECTIVES: To investigate whether(a) variants within the dopamine D 2 receptor gene(DRD
2) are associated with obesity and type 2 diabetes in Pima Indians, and(b) whether variation
in this gene could be responsible for previously observed linkage to these phenotypes, at ... Cited by 24 - Related articles - BL Direct - All 3 versions
DE Comings, SD Flanagan, G Dietz, D … - … medicine and metabolic …, 1993 - ncbi.nlm.nih.gov Dopamine plays a major role in the regulation of appetite and growth hormone. Dopaminergic
agonists suppress appetite and dopamine D2 receptor antagonists enhance it. We examined
the hypothesis that allelic variants of the DRD2 locus may be associated with weight and ... Cited by 80 - Related articles - BL Direct - All 3 versions
[CITATION] Identification of genes contributing to excess body fat and fat distribution
L Perusse, C Bouchard - Progress in obesity research: 7, 1996 - John Libbey Eurotext Cited by 10 - Related articles
- ►ahajournals.org GN Thomas, B Tomlinson, JAJH Critchley - Hypertension, 2000 - Am Heart Assoc Abstract—Pharmacological data suggest that obesity and blood pressure (BP) may be modulated
through the dopamine D2 receptor (DD2R), which may represent an underlying mechanism
that links these conditions. A TaqI polymorphism near the DD2R gene has been ... Cited by 50 - Related articles - BL Direct - All 5 versions
S Kamizono, K Yamada, N Seki, T Higuchi, A … - Tissue …, 2000 - interscience.wiley.com We have identified three novel polymorphisms in the promoter/enhancer region of the tumor
necrosis factor (TNF)-α gene. In this study we investigated the role of the polymorphisms in predisposition
to Type 2 diabetes. The allele frequency of C→T substitution at −857 tended to be higher ... Cited by 24 - Related articles - BL Direct - All 4 versions
GN Thomas, JAJH Critchley, B Tomlinson, … - Clinical …, 2001 - interscience.wiley.com It is also possible that your web browser is not configured or not able to display style sheets.
In this case, although the visual presentation will be degraded, the site should continue to be
functional. We recommend using the latest version of Microsoft or Mozilla web browser to ... Cited by 19 - Related articles - BL Direct - All 5 versions
M Lefevre, JC Lovejoy, SM DeFelice, JW Keener, … - International journal of …, 2000 - cat.inist.fr OBJECTIVE: To determine the relationship between two common apoA-IV variants(Thr 347
→Ser; Gln 360 →His), and body mass index(BMI) and percentage body fat. DESIGN:
Cross-sectional study. SUBJECTS: Eight-hundred and forty-eight subjects screened for ... Cited by 15 - Related articles - BL Direct - All 3 versions
W Ahmad, M De Fusco… - European journal of human genetics: EJHG - ncbi.nlm.nih.gov A new syndromic form of X-linked mental retardation associated to obesity, MRXS7, has been
localised to Xp11.3-Xq23 in a large Pakistani family. The ten affected males show clinical manifestations
of mental retardation, obesity and hypogonadism. The family was genotyped by a set of ... Cited by 9 - Related articles - BL Direct - All 2 versions