- ►diabetesjournals.org H Yamada, M Otsuka, M Hayashi, S … - Diabetes, 2001 - Am Diabetes Assoc Pancreatic islet cells express receptors and transporters for L-glutamate and
are thus believed to use L-glutamate as an intercellular signaling molecule.
However, the mechanism by which L-glutamate appears in the islets is ... Cited by 21 - Related articles - BL Direct - All 5 versions
H Yamada, M Otsuka, M Hayashi, S … - Diabetes, 2001 - Am Diabetes Assoc Page 1. Ca 2 -Dependent Exocytosis of L -Glutamate by TC6, Clonal Mouse
Pancreatic -Cells Hiroshi Yamada, 1 Masato Otsuka, 1 Mitsuko ... Cited by 6 - Related articles
- ►jbc.org CD Weaver, V Gundersen, TA Verdoorn - Journal of Biological Chemistry, 1998 - ASBMB To examine the role of glutamatergic signaling in the function of pancreatic
islets, we have characterized a high affinity glutamate/aspartate uptake system
in this tissue. The islet [ 3 H]glutamate uptake activity was Na + ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►biologists.org [PDF] Y Moriyama, M Hayashi, H Yamada, S … - Journal of Experimental Biology, 2000 - jeb.biologists.org Vacuolar H+-ATPases (V-ATPases) acidify various kinds of endomembrane systems
such as lysosomes and endosomes. Organelles containing V-ATPase are usually
called acidic organelles. An acidic pH or an electrochemical gradient of ... Cited by 38 - Related articles - BL Direct - All 4 versions
S Uehara, A Muroyama, N Echigo, R Morimoto … - Diabetes, 2004 - Am Diabetes Assoc In islets of Langerhans, l-glutamate is stored in glucagon-containing secretory
granules of α-cells and cosecreted with glucagon under low-glucose conditions.
The l-glutamate triggers secretion of γ-aminobutyric acid (GABA) from ... Cited by 25 - Related articles - BL Direct - All 5 versions
- ►physiology.org Q Tong, R Ouedraogo, AL Kirchgessner - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc Pancreatic islets contain ionotropic glutamate receptors that can modulate
hormone secretion. The purpose of this study was to determine whether islets
express functional group III metabotropic glutamate (mGlu) receptors. ... Cited by 29 - Related articles - BL Direct - All 5 versions
- ►jbc.org M Hayashi, H Yamada, S Uehara, R Morimoto … - Journal of Biological Chemistry, 2003 - ASBMB L-Glutamate is believed to function as an intercellular transmitter in the
islets of Langerhans. However, critical issues, ie where, when and how
L-glutamate appears, and what happens upon stimulation of glutamate ... Cited by 57 - Related articles - BL Direct - All 4 versions
- ►physiology.org L Bai, X Zhang, FK Ghishan - American Journal of Physiology- Gastrointestinal and …, 2003 - Am Physiological Soc Glutamate has been suggested to play an important role in the release of insulin
and glucagon from pancreatic cells via exocytosis. Vesicular glutamate
transporter is a rate-limiting step for glutamate release and is involved ... Cited by 27 - Related articles - BL Direct - All 4 versions
G Bertrand, R Gross, R Puech, MM … - Eur J Pharmacol, 1993 - grande.nal.usda.gov Title: Glutamate stimulates glucagon secretion via an excitatory amino acid
receptor of the AMPA subtype in rat pancreas. Author: Bertrand, G : Gross, R :
Puech, R : Loubatieres Mariani, MM : Bockaert, J Citation: Eur-J-Pharmacol. ... Cited by 47 - Related articles - Cached - All 3 versions
- ►cell.com Y Moriyama, M Hayashi - Trends in pharmacological sciences, 2003 - Elsevier Increasing evidence suggests that the excitatory neurotransmitter -glutamate
functions as a modulator in the islet of Langerhans, an endocrine organ involved
in blood glucose homeostasis. The islet is equipped with all the elements ... Cited by 21 - Related articles - All 8 versions