- ►diabetesjournals.org PM Larsen, SJ Fey, MR Larsen, A Nawrocki, HU … - Diabetes, 2001 - Am Diabetes Assoc The intracellular molecular events involved in the β-cell death process are
complex but poorly understood. Cytokines, eg, interleukin (IL)-1β, may play a
crucial role in inducing this process. Protein synthesis is necessary for ... Cited by 60 - Related articles - BL Direct - All 4 versions
HU Andersen, SJ Fey, PM Larsen, A Nawrocki, … - Electrophoresis, 1997 - interscience.wiley.com Insulin-dependent diabetes mellitus is caused by an autoimmune destruction of
the -cells in the islets of Langerhans. The cytokine interleukin 1 inhibits
insulin release and is selectively cytotoxic to -cells in isolated ... Cited by 34 - Related articles - BL Direct - All 3 versions
NE John, HU Andersen, SJ Fey, PM Larsen, P … - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc Interleukin-1 (IL-1 ) treatment of neonatal rat islets for 24 h induces changes
in the expression of 105 of 2,200 proteins, as determined previously by
two-dimen- sional (2D) gel electrophoresis. Nitric oxide (NO) has been ... Cited by 40 - Related articles - BL Direct - All 4 versions
UB Christensen, PM Larsen, SJ Fey, HU … - Autoimmunity, 2000 - informahealthcare.com J ' 2000 OPA (Ovcrseas Publishers A~socist~on) N V. Published by license under
the Harwood Academic Publishers Imprint. part of The Gordon and Breach
Publishing Group Printed in Maliiysia. ... BB-DP Rats and during Rejection of Cited by 24 - Related articles - BL Direct - All 6 versions
T Sparre, U Bjerre Christensen, P Mose Larsen … - Diabetologia, 2002 - Springer Aims/hypothesis. Type I (insulin-dependent) diabetes mellitus is characterized
by selective destruction of the insulin producing beta cells. Interleukin-1β
(IL-1β) modulates the beta-cell function, protein syn- thesis, energy ... Cited by 43 - Related articles - BL Direct - All 4 versions
HU Andersen, PM Larsen, SJ Fey, AE Karlsen … - Diabetes, 1995 - Am Diabetes Assoc Interleukin (IL)-1 beta-mediated damage to beta-cells in isolated islets of
Langerhans depends upon de novo synthesis of proteins that have not been fully
identified. Further, IL-1 beta-induced and tumor necrosis factor ... Cited by 40 - Related articles - BL Direct - All 5 versions
PM Larsen, SJ Fey, MR Larsen, A Nawrocki, HU … - Diabetes, 2001 - mitglied.lycos.de The intracellular molecular events involved in the ß-cell death process are
complex but poorly understood. Cy- tokines, eg, interleukin (IL)-1ß, may play a
crucial role in inducing this process. Protein synthesis is necessary for ... Related articles - View as HTML
- ►mcponline.org JC Sanchez, V Converset, A Nolan, G Schmid, … - Molecular & Cellular Proteomics, 2002 - ASBMB The insulin sensitizer drug, rosiglitazone, has been shown to have a protective
effect on pancreatic islet cell structure and function in animal models of type
2 diabetes. The identification of new molecular targets associated both ... Cited by 52 - Related articles - BL Direct - All 3 versions
K Nielsen, T Sparre, MR Larsen, M Nielsen, … - Diabetologia, 2004 - Springer Aim/hypothesis. Type 1 diabetes mellitus (T1DM) is caused by specific
destruction of the pancreatic beta cells in the islets of Langerhans. Increased
sensitivity to cytokines, in particular to interleukin-1β (IL-1β) seems ... Cited by 15 - Related articles - BL Direct - All 4 versions
J Nerup, T Mandrap-Poulsen, S Helqvist, HU … - Diabetologia, 1994 - Springer Dr. Nerup obtained his MD from the University of Copenhagen in 1964. He
completed postgraduate education in Copenhagen, Denmark, the Karolinska
Hospital, Stockholm, Sweden, and the Royal Hammersmith Hospital, London, ... Cited by 102 - Related articles - BL Direct - All 4 versions
