- ►diabetesjournals.org R Halse, SL Pearson, JG McCormack, SJ … - Diabetes, 2001 - Am Diabetes Assoc Reported discrepancies in the effects of tumor necrosis factor (TNF)-α in
modulating insulin sensitivity of cultured cells may relate both to cell types
studied and to the time course of exposure to the cytokine. Additionally, ... Cited by 66 - Related articles - BL Direct - All 4 versions
- ►physiology.org C Weigert, AM Hennige, K Brodbeck, HU … - American Journal of Physiology- Endocrinology And …, 2005 - Am Physiological Soc Previous studies showed an insulin-"desensitizing" action of IL-6 on glycogen
synthesis in hepatocytes. We recently found no inhibition of the proximal steps
of the insulin signal cascade in human skeletal muscle cells. Because these ... Cited by 46 - Related articles - BL Direct - All 4 versions
- ►bkpgroup.dk [PDF] P Keller, C Keller, AL Carey, S Jauffred, CP … - Biochemical and Biophysical Research …, 2003 - Elsevier Interleukin-6 (IL-6) is a cytokine with immuno-regulatory functions. However,
contracting skeletal muscle expresses and subsequently releases IL-6 in high
amounts, and recent evidence in IL-6 deficient mice suggests a role of IL-6 ... Cited by 57 - Related articles - All 7 versions
JM Youd, S Rattigan, MG Clark - Diabetes, 2000 - Am Diabetes Assoc The vascular actions of insulin may contribute to the increase in glucose uptake
by skeletal muscle. We have recently shown that when capillary recruitment by
insulin is blocked in vivo, an acute state of insulin resistance is ... Cited by 95 - Related articles - BL Direct - All 4 versions
DT Finegood - International journal of obesity and related metabolic …, 2003 - ncbi.nlm.nih.gov 1: Int J Obes Relat Metab Disord. 2003 Dec;27 Suppl 3:S4-5. Obesity,
inflammation and type II diabetes. Finegood DT. Institute of ... Cited by 12 - Related articles - BL Direct - All 3 versions
SE Borst, GJ Bagby - Metabolism, 2002 - Elsevier Between 7 and 14 weeks of age, male Sprague-Dawley (SD) rats exhibit a
substantial increase in adiposity and a corresponding decrease in
insulin-stimulated glucose transport in skeletal muscle. In SD rats aged 3 ... Cited by 15 - Related articles - BL Direct - All 6 versions
JM Fernández-Real, M Broch, W Ricart, R … - DIABETES-NEW YORK-, 1998 - Am Diabetes Assoc Recent studies have shown that the tumor necrosis fac- tor (TNF) system is
implicated in the insulin resistance of human obesity. Plasma concentrations of
the soluble fraction of the TNF receptors 1 and 2 (sTNFR1 and sTNFR2) are ... Cited by 155 - Related articles - BL Direct - All 4 versions
- ►physiology.org LF del Aguila, KP Claffey, JP Kirwan - American Journal of Physiology- Endocrinology And …, 1999 - Am Physiological Soc Physiological stressors such as sepsis and tissue damage initiate an acute
immune response and cause transient systemic insulin resistance. This study was
conducted to determine whether tumor necrosis factor- (TNF- ), a cytokine ... Cited by 123 - Related articles - All 3 versions
Y Mishima, A Kuyama, A Tada, K Takahashi, T … - Diabetes research and clinical practice, 2001 - Elsevier We analyzed serum concentrations of tumor necrosis factor-α (TNF-α) for their
role in insulin resistance in 12 obese men with untreated Type 2 diabetes
mellitus and in 6 age-and BMI-matched obese controls. Insulin resistance ... Cited by 104 - Related articles - All 8 versions