K Dutta, DA Podolin, MB Davidson, AJ … - Diabetes, 2001 - Am Diabetes Assoc Diabetes is associated with impaired cardiac dysfunction in both humans and
animals. Specific phenotypic changes—prolonged action potentials, slowed
cytosolic Ca 2+ clearing, and slowed relaxation—that contribute to this ... Cited by 65 - Related articles - BL Direct - All 5 versions
- ►physiology.org AJ Davidoff, MM Mason, MB Davidson, MW … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc We recently identified cardiomyocyte dysfunction in the early stage of type 2
diabetes (ie, diet-induced insulin resistance). The present investigation was
designed to determine whether a variety of clinically relevant ... Cited by 19 - Related articles - BL Direct - All 4 versions
- ►uwyo.edu [PDF] LE Wold, K Dutta, MM Mason, J Ren, SE Cala … - Journal of molecular and cellular cardiology, 2005 - Elsevier Ventricular dysfunction in type 2 diabetic patients is becoming apparent early
after diagnosis of diabetes, but the cellular mechanisms contributing to this
dysfunction are not well established. Our group has recently identified ... Cited by 24 - Related articles - All 11 versions
K Dutta, MW Carmody, SE Cala, AJ Davidoff - Journal of molecular and cellular cardiology, 2002 - Elsevier K. Dutta, MW Carmody, SE Cala and AJ Davidoff. Depressed PKA Activity
Contributes to Impaired SERCA Function and is Linked to the Pathogenesis of
Glucose-induced Cardiomyopathy. Journal of Molecular and Cellular ... Cited by 25 - Related articles - BL Direct - All 6 versions
- ►physiology.org J Ren, JR Sowers, MF Walsh, RA Brown - American Journal of Physiology- Heart and Circulatory …, 2000 - Am Physiological Soc Obesity plays a pivotal role in the pathophysiology of metabolic and
cardiovascular diseases. Resistance to insulin is commonly seen in metabolic
disorders such as obesity and diabetes. Insulin-like growth factor-I ... Cited by 71 - Related articles - BL Direct - All 4 versions
- ►physiology.org [PDF] J Ren, AJ Davidoff - American Journal of Physiology- Heart and Circulatory …, 1997 - Am Physiological Soc ITHAS BEENWELLESTABLISHED thatpatientswithdiabe- tes mellitus, both insulin
dependent and non-insulin dependent, exhibit a high incidence of cardiac
dysfunc- tion and mortality. A specific diabetic cardiomyopathy, ... Cited by 150 - Related articles - All 4 versions
- ►uwyo.edu [PDF] KK Hintz, J Ren - Diabetes research and clinical practice, 2002 - Elsevier Resistance to insulin-like growth factor I (IGF-1)-induced cardiac contractile
response has been reported in diabetes. To evaluate the role of prediabetic
insulin resistance to cardiac IGF-1 resistance, whole body insulin ... Cited by 10 - Related articles - All 11 versions
L Cai, YJ Kang - Cardiovascular Toxicology, 2001 - Springer *Author to whom all correspondence and reprint requests should be addressed: Y.
James Kang, Department of Medicine, University of Louisville School of Medicine,
511 S. Floyd St., MDR 530, Louisville, KY 40202. E-mail: yjkang01@athena. ... Cited by 108 - Related articles - All 3 versions
- ►physiology.org T Misra, JSC Gilchrist, JC Russell, GN Pierce - American Journal of Physiology- Heart and Circulatory …, 1999 - Am Physiological Soc Depressed myofibrillar Ca 2+ -ATPase activity and sarcoplasmic reticulum (SR) Ca
2+ uptake are important mechanisms that are responsible for the cardiac
dysfunction exhibited by insulin-deficient (type I) diabetic animals. The ... Cited by 15 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org [PDF] J Ren, LJ Dominguez, JR Sowers, AJ Davidoff - Diabetes, 1999 - Am Diabetes Assoc We have recently demonstrated that adult rat ventric- ular myocytes maintained
in a high glucose (HG) culture medium exhibit abnormalities in excitation-
contraction coupling similar to myocytes from diabetic rats. Metformin, an ... Cited by 36 - Related articles - BL Direct - All 5 versions
