F Cucca, F Dudbridge, M Loddo, AP Mulargia, R … - Diabetes, 2001 - Am Diabetes Assoc The major histocompatibility complex (MHC) HLA region on chromosome 6p21
contains the major locus of type 1 diabetes (IDDM1). Common allelic variants at
the class II HLA-DRB1, -DQA1, and -DQB1 loci account for the major part of ... Cited by 51 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org [PDF] JA Noble, AM Valdes, G Thomson, HA Erlich - Diabetes, 2000 - Am Diabetes Assoc HLA-DPB1 genotypes were determined for samples from 269 multiplex Caucasian
families from the Human Biological Data Interchange. DRB1 and DQB1 loci were
also characterized, allowing assignment of DPB1 alleles to haplotypes and ... Cited by 63 - Related articles - BL Direct - All 3 versions
HA Erlich, JI Rotter, JD Chang, SJ Shaw, LJ … - Diabetes, 1996 - Am Diabetes Assoc Susceptibility to IDDM has been associated with specific alleles at the HLA
class II loci in a variety of human populations. Previous studies among
Mexican-Americans, a group ancestrally derived from Native Americans and ... Cited by 57 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org TD Cruz, AM Valdes, A Santiago, T Frazer de … - Diabetes, 2004 - Am Diabetes Assoc Genetic associations between type 1 diabetes and alleles at the HLA class II
locus DPB1 have been previously reported. Observed associations could be due to
variation in the DPB1 locus itself or to linkage disequilibrium (LD) ... Cited by 17 - Related articles - BL Direct - All 4 versions
BA Lie, HE Akselsen, G Joner, K Dahl- … - Human immunology, 1997 - Elsevier Genes in the HLA complex are associated with susceptibility to develop
insulin-dependent diabetes mellitus (IDDM). Several studies, from different
populations, have demonstrated strong associations between particular DR ... Cited by 25 - Related articles - All 3 versions
JA Noble, AM Valdes, TL Bugawan, RJ Apple, … - Human immunology, 2002 - Elsevier Human leukocyte antigen A (HLA-A) genotypes were determined for samples from 283
multiplex, Caucasian, type 1 diabetes families from the Human Biological Data
Interchange (HBDI) using an immobilized probe assay. Distribution of HLA-A ... Cited by 56 - Related articles - All 4 versions
AM Valdes, JA Noble, E Génin, F Clerget- … - Genetic epidemiology, 2001 - interscience.wiley.com In this report, we present evidence that the HLA class II DPB1 locus (or a locus
with alleles in linkage disequilibrium with DPB1) contributes to Type I diabetes
(IDDM) susceptibility in addition to the contribution of the HLA DR and DQ ... Cited by 26 - Related articles - BL Direct - All 3 versions
- ►oxfordjournals.org P Zavattari, R Lampis, C Motzo, M Loddo, A … - Human Molecular Genetics, 2001 - Oxford Univ Press Type 1 diabetes mellitus is a common disease with a complex mode of inheritance.
Its aetiology is underpinned by a major locus, insulin-dependent diabetes
mellitus 1 (IDDM1) in the human leukocyte antigen (HLA) region of ... Cited by 63 - Related articles - BL Direct - All 9 versions
S Nejentsev, Z Gombos, AP Laine, R Veijola, … - DIABETES-NEW YORK-, 2000 - Am Diabetes Assoc Several studies provide evidence that in addition to the DQ-DR genes, HLA
contains another uncharacter- ized gene or genes associated with type 1
diabetes. Our aim was to investigate the effect of this gene indepen- ... Cited by 55 - Related articles - BL Direct - All 6 versions
- ►nih.gov [PDF] JA Noble, AM Valdes, M Cook, W Klitz, G … - American journal of human genetics, 1996 - pubmedcentral.nih.gov Janelle A. Noble,1'2 Ana M. Valdes,3 Margaret Cook,'2 William Klitz,3 Glenys
Thomson,3 and Henry A. Erlich1'2 ... 'Department of Human Genetics, Roche
Molecular Systems, Alameda; 2Children's Hospital Oakland Research ... Cited by 225 - Related articles - BL Direct - All 8 versions
