N Musi, N Fujii, MF Hirshman, I Ekberg, S Fröberg, O … - Diabetes, 2001 - Am Diabetes Assoc Insulin-stimulated GLUT4 translocation is impaired in people with type 2 diabetes. In
contrast, exercise results in a normal increase in GLUT4 translocation and glucose uptake in
these patients. Several groups have recently hypothesized that exercise increases ... Cited by 196 - Related articles - BL Direct - All 4 versions
N Musi, N Fujii, MF Hirshman, I Ekberg, S Fröberg, O … - Diabetes, 2001 - Am Diabetes Assoc Page 1. Rapid Publication AMP-Activated Protein Kinase (AMPK) Is Activated in Muscle
of Subjects With Type 2 Diabetes During Exercise Nicolas Musi, 1 Nobuharu Fujii,
1 Michael F. Hirshman, 1 Ingvar Ekberg, 2 Sven Fröberg, 2 ... Related articles - All 2 versions
- ►physoc.org JFP Wojtaszewski, P Nielsen, BF Hansen, EA … - The Journal of …, 2000 - Physiological Soc We investigated the degree of activation and deactivation of α-isoforms of AMPK during and
after exercise. Healthy human subjects performed bicycle exercise on two separate occasions
at either a low (∼50% maximum rate of O 2 uptake (V̇ O 2 ,max ) for 90 min) or a high (∼ ... Cited by 170 - Related articles - BL Direct - All 6 versions
N Fujii, T Hayashi, MF Hirshman, JT Smith, SA … - … and biophysical research …, 2000 - Elsevier The 5′AMP-activated protein kinase (AMPK) is stimulated by contractile activity in rat skeletal
muscle. AMPK has emerged as an important signaling intermediary in the regulation of cell metabolism
being linked to exercise-induced changes in muscle glucose and fatty acid metabolism. In ... Cited by 186 - Related articles - BL Direct - All 5 versions
- ►physiology.org K Hojlund, KJ Mustard, P Staehr, DG … - American Journal of …, 2004 - Am Physiological Soc Acute or chronic activation of AMP-activated protein kinase (AMPK) increases insulin
sensitivity. Conversely, reduced expression and/or function of AMPK might play a role in insulin
resistance in type 2 diabetes. Thus protein expression of the seven subunit isoforms of ... Cited by 37 - Related articles - BL Direct - All 4 versions
- ►physiology.org ZP Chen, GK McConell, BJ Michell, RJ … - American Journal of …, 2000 - Am Physiological Soc AMP-activated protein kinase (AMPK) is a metabolic stress-sensing protein kinase responsible
for coordinating metabolism and energy demand. In rodents, exercise accelerates fatty acid
metabolism, enhances glucose uptake, and stimulates nitric oxide (NO) production in ... Cited by 161 - Related articles - BL Direct - All 3 versions
- ►physiology.org N Musi, T Hayashi, N Fujii, MF Hirshman, … - American Journal of …, 2001 - Am Physiological Soc The AMP-activated protein kinase (AMPK) has been hypothesized to mediate contraction and
5-aminoimidazole-4-carboxamide 1- -D-ribonucleoside (AICAR)-induced increases in glucose
uptake in skeletal muscle. The purpose of the current study was to determine whether ... Cited by 132 - Related articles - BL Direct - All 3 versions
- ►physiology.org TJ Stephens, ZP Chen, BJ Canny, BJ … - American Journal of …, 2002 - Am Physiological Soc The effect of prolonged moderate-intensity exercise on human skeletal muscle AMP-activated
protein kinase (AMPK) 1 and - 2 activity and acetyl-CoA carboxylase (ACC ) and neuronal nitric
oxide synthase (nNOSµ) phosphorylation was investigated. Seven active healthy ... Cited by 82 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org HA Koistinen, D Galuska, AV Chibalin, J Yang, JR … - Diabetes, 2003 - Am Diabetes Assoc AMP-activated protein kinase (AMPK) activation by AICAR (5-amino-imidazole carboxamide
riboside) is correlated with increased glucose transport in rodent skeletal muscle via an
insulin-independent pathway. We determined in vitro effects of insulin and/or AICAR ... Cited by 97 - Related articles - BL Direct - All 7 versions
J Mu, JT Brozinick, O Valladares, M Bucan, MJ … - Molecular cell, 2001 - cell.com Eukaryotic cells possess systems for sensing nutritional stress and inducing compensatory mechanisms
that minimize the consumption of ATP while utilizing alternative energy sources. Such stress
can also be imposed by increased energy needs, such as in skeletal muscle of exercising ... Cited by 485 - Related articles - All 7 versions
