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Scholar Results 1 - 10 of about 101 related to Lochhead: Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphoenolpyruvate.... (0.10 sec) 

Inhibition of GSK-3 selectively reduces glucose-6-phosphatase and phosphoenolpyruvate …


PA Lochhead, M Coghlan, SQJ Rice, C … - Diabetes, 2001 - Am Diabetes Assoc
A major action of insulin is to regulate the transcription rate of specific
genes. The expression of these genes is dramatically altered in type 2 diabetes.
For example, the expression of two hepatic genes, glucose-6-phosphatase and ...
Cited by 42 - Related articles - BL Direct - All 3 versions

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CG Expression - Diabetes, 2001 - Am Diabetes Assoc
A major action of insulin is to regulate the transcription rate of specific
genes. The expression of these genes is dramatically altered in type 2 diabetes.
For example, the expression of two hepatic genes, glucose-6-phospha- tase ...
Related articles

[CITATION] Inhibition of GSK3 by insulin mediated by protein kinase B


DAE Cross, DR Alessi, P Cohen, M … - Nature, 1995
Cited by 14 - Related articles

[CITATION] Effects of a novel GSK3 inhibitor on insulin stimulated glucose metabolism in ZDF (fa/fa) rats


GW Cline, K Johnson, W Regittnig, P Perret, … - Diabetes, 2002
Cited by 6 - Related articles

Insulin regulation of IGF-binding protein-1 gene expression is dependent on mammalian …


S Patel, PA Lochhead, G Rena, S Fumagalli, … - Journal of Biological Chemistry, 2002 - ASBMB
Insulin inhibits the expression of the hepatic IGFBP-1 and glucose-6-phosphatase
(G6Pase) genes. The signalling pathway that mediates these events requires the
activation of phosphatidylinositol 3-kinase, while transfection studies ...
Cited by 8 - Related articles

[CITATION] Phosphorylation of Ser 256 by PKB disrupts transactivation by FKHR and mediates effects of …


S Guo, G Rena, S Cichy, X He, P Cohen, TG … - J Biol Chem, 1999
Cited by 7 - Related articles

Modulation of muscle insulin resistance by selective inhibition of GSK-3 in Zucker diabetic …

- physiology.org
EJ Henriksen, TR Kinnick, MK Teachey, MP O … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc
A role for elevated glycogen synthase kinase-3 (GSK-3) activity in the
multifactorial etiology of insulin resistance is now emerging. However, the
utility of specific GSK-3 inhibition in modulating insulin resistance of ...
Cited by 57 - Related articles - BL Direct - All 5 versions

Different mechanisms are used by insulin to repress three genes that contain a homologous …


S Patel, C Lipina, C Sutherland - FEBS letters, 2003 - Elsevier
Insulin rapidly and completely inhibits expression of the hepatic insulin-like
growth factor binding protein-1 (IGFBP-1), phosphoenolpyruvate carboxykinase
(PEPCK) and glucose-6-phosphatase (G6Pase) genes. This inhibition is ...
Cited by 9 - Related articles - All 5 versions

Glycogen synthase kinase-3 regulates IGFBP-1 gene transcription through the thymine-rich …


D Finlay, S Patel, LM Dickson, N Shpiro, R … - BMC Molecular Biology, 2004 - biomedcentral.com
Hepatic expression of several gene products involved in glucose metabolism,
including phosphoenolpyruvate carboxykinase (PEPCK), glucose-6-phosphatase
(G6Pase) and insulin-like growth factor binding protein-1 (IGFBP-1), is ...
Cited by 26 - Related articles - Cached - All 8 versions

[CITATION] PI 3-kinase and p70S6 kinase are required for insulin but not bisperoxovanadium 1, 10- …


CJ Band, BI Posner - J Biol Chem, 1997
Cited by 5 - Related articles


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