- ►diabetesjournals.org A Antonelli, G Baj, P Marchetti, P Fallahi, N … - Diabetes, 2001 - Am Diabetes Assoc CD38 is involved in transmembrane signaling in many cell types; anti-CD38
autoantibodies have been described in diabetic patients. We tested whether human
anti-CD38 antibodies possess signaling properties by measuring their ... Cited by 30 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] C Pupilli, S Giannini, P Marchetti, R Lupi, A … - Diabetes, 1999 - Am Diabetes Assoc The type II transmembrane glycoprotein CD38 (ADP- ribosyl cyclase/cyclic
ADP-ribose hydrolase) has been proposed as a mediator of insulin secretion from
pan- creatic -cells and as a candidate for autoimmune reac- tions in type 2 ... Cited by 39 - Related articles - BL Direct - All 5 versions
R Mallone, E Ortolan, G Baj, A Funaro, S … - Diabetes, 2001 - Am Diabetes Assoc Insulin secretion is one of the functions mediated by CD38, a nonlineage
pleiotropic cell surface receptor. The molecule is the target of an autoimmune
response, because serum autoantibodies (aAbs) to CD38 have been detected in ... Cited by 25 - Related articles - BL Direct - All 4 versions
R Mallone, E Ortolan, S Pinach, M Volante, M … - Diabetologia, 2002 - Springer Aims/hypothesis. Serum anti-CD38 autoantibodies (aAbs) have been reported in 17
to 19% of patients with long-standing Type I (insulin-dependent) diabe- tes
mellitus and Type II (non-insulin-dependent) dia- betes mellitus. Whether ... Cited by 14 - Related articles - BL Direct - All 5 versions
A Antonelli, T Tuomi, M Nannipieri, P Fallahi, … - Diabetologia, 2002 - Springer Aims/hypothesis. Autoantibodies against CD38 have been found in some patients
with Type II (non-insulin- dependent) diabetes mellitus and have been shown to
stimulate insulin secretion by cultured human islets. We tested whether ... Cited by 27 - Related articles - BL Direct - All 4 versions
H Okamoto, S Takasawa, K Nata - Diabetologia, 1997 - Springer In answer to the comments of Islam and Berggren concerning our hypothesis on the
CD38-cyclic ADP- ribose (cADPR) signalling system, we will present several lines
of evidence that we believe can explain the discrepancies between their ... Cited by 44 - Related articles - BL Direct - All 4 versions
NH An, MK Han, C Um, BH Park, BJ Park, HK … - Biochemical and Biophysical Research …, 2001 - Elsevier Cyclic ADP-ribose (cADPR), a product of CD38, has a second messenger role for in
intracellular Ca 2+ mobilization from microsomes of pancreatic islets as well as
from a variety of other cells. ADP-ribosylation of CD38 by ecto-mono ADP- ... Cited by 18 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org P Marchetti, A Antonelli, R Lupi, L Marselli, P … - Diabetes, 2002 - Am Diabetes Assoc Autoantibodies against CD38 (adenosine-5′-diphosphate[ADP]-ribosyl
cyclase/cyclic ADP-ribose hydrolase) have been described in 10–12% of patients
with type 2 diabetes. In human islets, anti-CD38 autoantibodies (CD38Abs) ... Cited by 6 - Related articles - BL Direct - All 3 versions
JE Fernandez, S Deaglio, D Donati, IS Beusan, … - Journal of biological regulators and homeostatic … - ncbi.nlm.nih.gov 1: J Biol Regul Homeost Agents. 1998 Jul-Sep;12(3):81-91. Analysis of the
distribution of human CD38 and of its ligand CD31 in normal tissues. ... Cited by 66 - Related articles - BL Direct - All 3 versions
