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Successful reversal of streptozotocin-induced diabetes with stable allogeneic islet function …


JM Thomas, JL Contreras, CA Smyth, A … - Diabetes, 2001 - Am Diabetes Assoc
The recent focus on islet transplantation as primary therapy for type 1 diabetes
has heightened interest in the reversal of type 1 diabetes in preclinical models
using minimal immunosuppression. Here, we demonstrated in a preclinical ...
Cited by 65 - Related articles - BL Direct - All 10 versions

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JM Thomas, JL Contreras, CA Smyth, A … - DIABETES, 2001 - Am Diabetes Assoc
The recent focus on islet transplantation as primary therapy for type 1 diabetes
has heightened interest in the reversal of type 1 diabetes in preclinical models
us- ing minimal immunosuppression. Here, we demonstrat- ed in a preclinical ...
Related articles

DURABLE DONOR-SPECIFIC T AND B CELL TOLERANCE IN RHESUS MACAQUES INDUCED …

- prsjournal.net
JM Thomas, DE Eckhoff, JL Contreras, AL … - Transplantation, 2000 - journals.lww.com
Skip Navigation Links Home > June 27, 2000 - Volume 69 - Issue 12 > DURABLE
DONOR-SPECIFIC T AND B CELL TOLERANCE IN RHESUS MACA... ... Thomas, Judith M.;
Eckhoff, Devin E.; Contreras, Juan L.; Lobashevsky, Andrew L.; Hubbard, ...
Cited by 71 - Related articles - BL Direct - All 6 versions

Calcineurin inhibitor–free CD28 blockade-based protocol protects allogeneic islets in …

- diabetesjournals.org
AB Adams, N Shirasugi, MM Durham, E … - Diabetes, 2002 - Am Diabetes Assoc
Recent success using a steroid-free immunosuppressive regimen has renewed
enthusiasm for the use of islet transplantation to treat diabetes. Toxicities
associated with the continued use of a calcineurin inhibitor may limit the ...
Cited by 98 - Related articles - BL Direct - All 4 versions

Phenotypic and functional analysis of T-cell recovery after anti-CD3 immunotoxin treatment …


WJ Hubbard, JK Moore, JL Contreras, CA … - Human Immunology, 2001 - Elsevier
T-cell reduction utilizing specific antibody has been widely used in human
transplantation, and is a cornerstone of several tolerance induction strategies
in nonhuman primates. We have established a population of long-term ...
Cited by 19 - Related articles - BL Direct - All 3 versions

Long-term functional islet mass and metabolic function after xenoislet transplantation in …


JL Contreras, DE Eckhoff, S Cartner, G … - Transplantation, 2000 - ncbi.nlm.nih.gov
BACKGROUND: Pancreatic islet transplantation (PIT) is an attractive alternative
for patients with type I diabetes mellitus. PIT is not yet an effective clinical
reality due in part to the high incidence of rejection and early loss of ...
Cited by 31 - Related articles - BL Direct - All 2 versions

Identification of DRB alleles in rhesus monkeys using polymerase chain reaction-sequence- …


A Lobashevsky, JP Smith, J Kasten-Jolly, H … - Tissue Antigens, 1999 - interscience.wiley.com
Major histocompatibility complex (MHC) class II molecules play a vital role in
the regulation of T-cell functions in the mammalian immune system. Two key
features characterize the polymorphism of MHC haplotypes in humans and ...
Cited by 32 - Related articles - BL Direct - All 4 versions

Reversal of Naturally Occurring Diabetes in Primates By Unmodified Islet Xenografts …


FT Thomas, C Ricordi, JL Contreras, WJ … - Transplantation, 1999 - journals.lww.com
Thomas, Francis T.; Ricordi, Camillo; Contreras, Juan L.; Hubbard, William J.;
Jiang, Xiao Ling; Eckhoff, Devin E.; Cartner, Samuel; Bilbao, Guadalupe;
Neville, David M. Jr.; Thomas, Judith M. ... 2 Division of Transplantation ...
Cited by 60 - Related articles - BL Direct - All 3 versions

STEALTH matters: a novel paradigm of durable primate allograft tolerance


JM Thomas, WJ Hubbard, SK Sooudi, FT … - Immunological reviews, 2001 - interscience.wiley.com
Summary: We review a novel strategy for tolerance induction developed in rhesus
macaques and termed STEALTH. We summarize the evolution of the STEALTH model,
the results of successful trials in inducing long-term, stable transplant ...
Cited by 26 - Related articles - BL Direct - All 5 versions

PERITRANSPLANT TOLERANCE INDUCTION WITH ANTI-CD3-IMMUNOTOXIN: A Matter of …


JL Contreras, PX Wang, DE Eckhoff, AL … - Transplantation, 1998 - journals.lww.com
Contreras, Juan L.; Wang, Pei X.; Eckhoff, Devin E.; Lobashevsky, Andrew L.;
Asiedu, Clement; Frenette, Luc; Robbin, Michelle L.; Hubbard, William J.;
Cartner, Samuel; Nadler, Steven; Cook, William J.; Sharff, Joshua; ...
Cited by 69 - Related articles - BL Direct - All 5 versions


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