- ►diabetesjournals.org KF Petersen, D Laurent, C Yu, GW Cline, GI … - Diabetes, 2001 - Am Diabetes Assoc Fructose has been shown to have a catalytic effect on glucokinase activity in
vitro; however, its effects on hepatic glycogen metabolism in humans is unknown.
To address this question, we used 13 C nuclear magnetic resonance (NMR) ... Cited by 35 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org [PDF] M Shiota, P Galassetti, M Monohan, DW Neal, … - Diabetes, 1998 - Am Diabetes Assoc Fructose activates glucokinase by releasing the enzyme from its inhibitory
protein in liver. To examine the impor- tance of acute activation of glucokinase
in regulating hepatic glucose uptake, the effect of intraportal infusion of ... Cited by 60 - Related articles - BL Direct - All 6 versions
M Hawkins, I Gabriely, R Wozniak, C Vilcu, H … - Diabetes, 2002 - Am Diabetes Assoc The ability of hyperglycemia per se to suppress endogenous glucose production
(GP) is blunted in type 2 diabetes. This could be due in part to decreased
glucose-induced flux through glucokinase (GK). Because fructose activates ... Cited by 41 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org MC Moore, SN Davis, SL Mann, AD … - Diabetes Care, 2001 - Am Diabetes Assoc RESULTS—The area under the curve (AUC) of the plasma glucose response was
reduced by fructose administration in all subjects; the mean AUC during the OGTT
+ F was 14% less than that during the OGTT – F (P < 0.05). The insulin ... Cited by 60 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org M Shiota, MC Moore, P Galassetti, M … - Diabetes, 2002 - Am Diabetes Assoc Intraportal infusion of small amounts of fructose markedly augmented net hepatic
glucose uptake (NHGU) during hyperglycemic hyperinsulinemia in conscious dogs.
In this study, we examined whether the inclusion of catalytic amounts of ... Cited by 28 - Related articles - BL Direct - All 6 versions
C Fillat, AM Gomez-Foix, JJ Guinovart - Archives of biochemistry and biophysics, 1993 - ncbi.nlm.nih.gov In rat hepatocytes fructose at low concentrations (below 1 mM) stimulated the
glycolytic flux as measured by the release of 3H2O from [3-3H]glucose and
increased fructose 2,6-bisphosphate [Fru(2,6)P2] levels, without modifying ... Cited by 13 - Related articles - BL Direct - All 3 versions
- ►endojournals.org MC Moore, AD Cherrington, SL Mann, SN … - Journal of Clinical Endocrinology & Metabolism, 2000 - Endocrine Soc In animal models, a small (catalytic) dose of fructose administered with glucose
decreases the glycemic response to the glucose load. Therefore, we examined the
effect of fructose on glucose tolerance in 11 healthy human volunteers (5 ... Cited by 47 - Related articles - BL Direct - All 5 versions
[CITATION] Consuming high fructose meals reduces 24 hour plasma insulin and leptin concentrations, …
CB Niewoehner, BQ Nuttall, FQ Nuttall - Metabolism: clinical and experimental, 1987 - ncbi.nlm.nih.gov 1: Metabolism. 1987 Apr;36(4):338-44. Effects of graded intravenous doses of
fructose on glycogen synthase in the liver of fasted rats. ... Cited by 10 - Related articles - All 3 versions
- ►nutrition.org BW Wolf, PM Humphrey, CW Hadley, KS … - Journal of Nutrition, 2002 - Am Soc Nutrition Experiments were conducted to evaluate the effects of supplemental fructose on
postprandial glycemia. After overnight food deprivation, Zucker fatty fa/fa rats
were given a meal glucose tolerance test. Plasma glucose response was ... Cited by 11 - Related articles - BL Direct - All 7 versions
