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Scholar Results 1 - 10 of about 101 related to Lajoix: A neuronal isoform of nitric oxide synthase expressed in pancreatic β-cells controls.... (0.11 sec) 

A neuronal isoform of nitric oxide synthase expressed in pancreatic β-cells controls …

- diabetesjournals.org
AD Lajoix, H Reggio, T Chardès, S Péraldi-Roux, F … - Diabetes, 2001 - Am Diabetes Assoc
Evidence is presented showing that a neuronal isoform of nitric oxide synthase (NOS) is expressed
in rat pancreatic islets and INS-1 cells. Sequencing of the coding region indicated a 99.8% homology
with rat neuronal NOS (nNOS) with four mutations, three of them resulting in modifications ...
Cited by 61 - Related articles - BL Direct - All 5 versions

Endogenous nitric oxide inhibits glucose-induced insulin secretion by suppression …


Y Tsuura, H Ishida, T Shinomura, M Nishimura, Y … - … and Biophysical Research …, 1998 - Elsevier
The physiological role of nitric oxide (NO) on the mechanism of insulin secretion is unknown,
but some studies suggest that NO affects glucose metabolism in pancreatic β-cells. We have
aimed at clarifying the physiological role of endogenous NO and its target in the glucose ...
Cited by 36 - Related articles - BL Direct - All 6 versions

Role of nitric oxide synthase isoforms in glucose-stimulated insulin release

- physiology.org
R Henningsson, A Salehi, I … - American Journal of …, 2002 - Am Physiological Soc
The role of islet constitutive nitric oxide synthase (cNOS) in insulin-releasing mechanisms is
controversial. By measuring enzyme activities and protein expression of NOS isoforms [ie, cNOS
and inducible NOS (iNOS)] in islets of Langerhans cells in relation to insulin secretion, we ...
Cited by 39 - Related articles - BL Direct - All 5 versions

Islet constitutive nitric oxide synthase: biochemical determination and regulatory …


A Salehi, M Carlberg, R Henningson, I … - American Journal of …, 1996 - Am Physiological Soc
Page 1. Islet constitutive nitric oxide synthase: biochemical determination and
regulatory function ALBERT SALEHI, MATS CARLBERG, RAGNAR HENNINGSON,
AND INGMAR LUNDQUIST Departments of Pharmacology and ...
Cited by 72 - Related articles - BL Direct - All 4 versions

Islet constitutive nitric oxide synthase and glucose regulation of insulin release in …

- endocrinology-journals.org [PDF] 
B Akesson, R Henningsson, A Salehi, I … - Journal of …, 1999 - Soc Endocrinology
We have studied, by a combined in vitro and in vivo approach, the relation between the inhibitory
action of NG-nitro--arginine methyl ester (L-NAME), a selective inhibitor of nitric oxide synthase
(NOS), on the activity of islet constitutive NOS (cNOS) and glucose regulation of islet ...
Cited by 32 - Related articles - BL Direct - All 6 versions

Morphological evidence for the existence of nitric oxide and carbon monoxide …


P Alm, P Ekström, R Henningsson, I Lundquist - Diabetologia, 1999 - Springer
Aims/hypothesis. To map the cellular location of in- ducible and constitutive nitric oxide synthase
and haem oxygenase in rat islets to clarify the morpholog- ical background to putative nitric oxide
and carbon monoxide pathways. Methods. Immunocytochemistry and confocal mi- ...
Cited by 53 - Related articles - BL Direct - All 4 versions

Total parenteral nutrition modulates hormone release by stimulating expression …


A Salehi, M Ekelund, R Henningsson, I Lundquist - Endocrine, 2001 - Springer
Received June 21, 2001; Revised October 5, 2001; Accepted October 8, 2001. Author to whom
all correspondence and reprint requests should be addressed: Dr. Albert Salehi, Institute of Physiological
Sciences, Department of Phar- macology, BMC F13, S-221 84 Lund, Sweden. E-mail: ...
Cited by 22 - Related articles - BL Direct - All 4 versions

Exogenous nitric oxide and endogenous glucose-stimulated β-cell nitric oxide …


SR Smukler, L Tang, MB Wheeler, AMF Salapatek - Diabetes, 2002 - Am Diabetes Assoc
The role nitric oxide (NO) plays in physiological insulin secretion has been controversial. Here
we present evidence that exogenous NO stimulates insulin secretion, and that endogenous NO
production occurs and is involved in the regulation of insulin release. Radioimmunoassay ...
Cited by 49 - Related articles - BL Direct - All 7 versions

Chronic blockade of NO synthase paradoxically increases islet NO production and …

- physiology.org
R Henningsson, P Alm, E Lindstrom, I … - American Journal of …, 2000 - Am Physiological Soc
Islet production of nitric oxide (NO) and CO in relation to islet hormone secretion was investigated
in mice given the NO synthase (NOS) inhibitor N G -nitro-L-arginine methyl ester (L-NAME) in
their drinking water. In these mice, the total islet NO production was paradoxically ...
Cited by 32 - Related articles - BL Direct - All 3 versions

Total parenteral nutrition-stimulated activity of inducible nitric oxide synthase in rat …


A Salehi, M Ekelund, I Lundquist - Hormone and Metabolic …, 2003 - thieme-connect.com
Long-term total parenteral nutrition (TPN) is associated with elevated plasma lipids and a marked
decrease of glucose-stimulated insulin release. Since nitric oxide (NO) has been shown to modulate
negatively the insulin response to glucose, we investigated the influence of ...
Cited by 20 - Related articles - BL Direct - All 5 versions


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