- ►diabetesjournals.org M van Heek, TM Austin, C Farley, JA Cook, GG … - Diabetes, 2001 - Am Diabetes Assoc Ezetimibe potently and selectively inhibits cholesterol absorption in the
intestine, thereby reducing plasma cholesterol in preclinical models of
hypercholesterolemia. Clinical trials have demonstrated that ezetimibe ... Cited by 55 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org HR Davis Jr, DS Compton, L Hoos, G Tetzloff - Arteriosclerosis, thrombosis, and vascular biology, 2001 - Am Heart Assoc Ezetimibe (SCH58235) is a potent, selective, cholesterol absorption inhibitor.
The objective of this study was to determine whether ezetimibe reduces plasma
cholesterol and inhibits atherogenesis in apolipoprotein E knockout ... Cited by 140 - Related articles - BL Direct - All 9 versions
HR Davis, KK Pula, KB Alton, RE Burrier, RW … - Metabolism, 2001 - Elsevier Ezetimibe (SCH 58235) and SCH 48461 are potent cholesterol absorption
inhibitors, which cause significant decreases in plasma cholesterol levels in
cholesterol-fed animals and in humans with hypercholesterolemia. These ... Cited by 84 - Related articles - BL Direct - All 7 versions
M van Heek, DS Compton, HR Davis - European journal of pharmacology, 2001 - Elsevier Ezetimibe (1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-
(4-hydroxyphenyl)-2-azetidinone) potently and selectively inhibits the
intestinal absorption of cholesterol, thereby reducing plasma cholesterol ... Cited by 105 - Related articles - All 6 versions
W Kramer, H Glombik, S Petry, H Heuer, HL … - FEBS letters, 2000 - Elsevier To identify protein components of the intestinal cholesterol transporter, rabbit
small intestinal brush border membrane vesicles were submitted to photoaffinity
labeling using photoreactive derivatives of 2-azetidinone cholesterol ... Cited by 63 - Related articles - All 6 versions
M Van Heek, C Farley, DS Compton, L Hoos, … - British journal of pharmacology, 2001 - pubmedcentral.nih.gov Ezetimibe reduced plasma cholesterol and hepatic cholesterol accumulation in
cholesterol-fed hamsters with an ED 50 of 0.04 mg kg −1 . Utilizing
cholesteryl esters labelled on either the cholesterol or the fatty acid ... Cited by 131 - Related articles - BL Direct - All 4 versions
TA Miettinen - INTERNATIONAL JOURNAL OF CLINICAL PRACTICE …, 2001 - 万方数据资源系统 A clear relationship has been documented between plasma levels of low-density
lipoprotein cholesterol (LDL-C) and the risk of coronary heart disease. LDL-C is
believed to be key in the pathogenesis of coronary atherosclerosis, ... Cited by 41 - Related articles - BL Direct - All 6 versions
[CITATION] Lack of a pharmacokinetic interaction between ezetimibe and atorvastatin