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Scholar Results 1 - 10 of about 101 related to van Heek: Ezetimibe, a potent cholesterol absorption inhibitor, normalizes combined dyslipidemia.... (0.14 sec) 

Ezetimibe, a potent cholesterol absorption inhibitor, normalizes combined dyslipidemia in …

- diabetesjournals.org
M van Heek, TM Austin, C Farley, JA Cook, GG … - Diabetes, 2001 - Am Diabetes Assoc
Ezetimibe potently and selectively inhibits cholesterol absorption in the
intestine, thereby reducing plasma cholesterol in preclinical models of
hypercholesterolemia. Clinical trials have demonstrated that ezetimibe ...
Cited by 55 - Related articles - BL Direct - All 5 versions

Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of …

- ahajournals.org
HR Davis Jr, DS Compton, L Hoos, G Tetzloff - Arteriosclerosis, thrombosis, and vascular biology, 2001 - Am Heart Assoc
Ezetimibe (SCH58235) is a potent, selective, cholesterol absorption inhibitor.
The objective of this study was to determine whether ezetimibe reduces plasma
cholesterol and inhibits atherogenesis in apolipoprotein E knockout ...
Cited by 140 - Related articles - BL Direct - All 9 versions

The synergistic hypocholesterolemic activity of the potent cholesterol absorption inhibitor, …


HR Davis, KK Pula, KB Alton, RE Burrier, RW … - Metabolism, 2001 - Elsevier
Ezetimibe (SCH 58235) and SCH 48461 are potent cholesterol absorption
inhibitors, which cause significant decreases in plasma cholesterol levels in
cholesterol-fed animals and in humans with hypercholesterolemia. These ...
Cited by 84 - Related articles - BL Direct - All 7 versions

The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced …


M van Heek, DS Compton, HR Davis - European journal of pharmacology, 2001 - Elsevier
Ezetimibe (1-(4-fluorophenyl)-(3R)-[3-(4-fluorophenyl)-(3S)-hydroxypropyl]-(4S)-
(4-hydroxyphenyl)-2-azetidinone) potently and selectively inhibits the
intestinal absorption of cholesterol, thereby reducing plasma cholesterol ...
Cited by 105 - Related articles - All 6 versions

Identification of binding proteins for cholesterol absorption inhibitors as components of the …


W Kramer, H Glombik, S Petry, H Heuer, HL … - FEBS letters, 2000 - Elsevier
To identify protein components of the intestinal cholesterol transporter, rabbit
small intestinal brush border membrane vesicles were submitted to photoaffinity
labeling using photoreactive derivatives of 2-azetidinone cholesterol ...
Cited by 63 - Related articles - All 6 versions

Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence …


M Van Heek, C Farley, DS Compton, L Hoos, … - British journal of pharmacology, 2001 - pubmedcentral.nih.gov
Ezetimibe reduced plasma cholesterol and hepatic cholesterol accumulation in
cholesterol-fed hamsters with an ED 50 of 0.04 mg kg −1 . Utilizing
cholesteryl esters labelled on either the cholesterol or the fatty acid ...
Cited by 131 - Related articles - BL Direct - All 4 versions

Cholesterol absorption inhibition: a strategy for cholesterol-lowering therapy


TA Miettinen - INTERNATIONAL JOURNAL OF CLINICAL PRACTICE …, 2001 - 万方数据资源系统
A clear relationship has been documented between plasma levels of low-density
lipoprotein cholesterol (LDL-C) and the risk of coronary heart disease. LDL-C is
believed to be key in the pathogenesis of coronary atherosclerosis, ...
Cited by 41 - Related articles - BL Direct - All 6 versions

[CITATION] Lack of a pharmacokinetic interaction between ezetimibe and atorvastatin


Y Zhu, P Statkevich, T Kosoglou, SE Maxwell, … - Clin Pharmacol Ther, 2001
Cited by 30 - Related articles

[CITATION] No pharmacokinetic drug interaction between ezetimibe and lovastatin


L Reyderman, T Kosoglou, P Statkevich, L … - Clin Pharmacol Ther, 2001
Cited by 35 - Related articles

[CITATION] Ezetimibe does not affect the pharmacokinetics or pharmacodynamics of warfarin


KS Bauer, T Kosoglou, P Statkevich, A … - Clin Pharmacol Ther, 2001
Cited by 36 - Related articles


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