- ►diabetesjournals.org A Basu, R Basu, P Shah, A Vella, CM Johnson, M … - Diabetes, 2001 - Am Diabetes Assoc We have previously reported that splanchnic glucose uptake, hepatic glycogen synthesis, and
hepatic glucokinase activity are decreased in people with type 2 diabetes during intravenous
glucose infusion. To determine whether these defects are also present during more ... Cited by 63 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] A Basu, R Basu, P Shah, A Vella, CM Johnson, KS Nair … - Diabetes, 2000 - Am Diabetes Assoc Insulin-induced stimulation of muscle glucose uptake (MGU) is impaired in people with type 2
diabetes. To determine whether insulin-induced stimulation of splanchnic glucose uptake
(SGU) is also impaired, we simultaneously measured leg glucose uptake (LGU) and SGU ... Cited by 77 - Related articles - BL Direct - All 5 versions
- ►nih.gov [PDF] B Ludvik, JJ Nolan, A Roberts, J Baloga, … - Journal of Clinical …, 1997 - pubmedcentral.nih.gov The role of splanchnic glucose uptake (SGU) after oral glu- cose administration as a potential
factor contributing to post- prandial hyperglycemia in non–insulin-dependent diabetes mellitus
(NIDDM) has not been established conclusively. Therefore, we investigated SGU in six ... Cited by 52 - Related articles - BL Direct - All 12 versions
MF Nielsen, R Basu, S Wise, A Caumo, C … - DIABETES-NEW …, 1998 - Am Diabetes Assoc The present studies were undertaken to determine whether people with type 2 diabetes are resistant
to the effects of glucose as well as insulin. Diabetic and nondiabetic subjects were studied on
three occasions. Hormone secretion was inhibited with somatostatin. Insulin ... Cited by 45 - Related articles - BL Direct - All 5 versions
P Shah, A Vella, A Basu, R Basu, A Adkins, WF … - Diabetes, 2002 - Am Diabetes Assoc The present study sought to determine whether elevated plasma free fatty acids (FFAs) alter
the ability of insulin and glucose to regulate splanchnic as well as muscle glucose
metabolism. To do so, FFAs were increased in 10 subjects to ∼1 mmol/l by an 8-h ... Cited by 38 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org A Gastaldelli, E Toschi, M Pettiti, S Frascerra, A … - Diabetes, 2001 - Am Diabetes Assoc Gluconeogenesis (GNG) is enhanced in type 2 diabetes. In experimental animals, insulin at high
doses decreases the incorporation of labeled GNG precursors into plasma glucose. Whether
physiological hyperinsulinemia has any effect on total GNG in humans has not been ... Cited by 63 - Related articles - BL Direct - All 5 versions
J Radziuk, S Pye - Diabetologia, 2001 - Springer The relative importance of glucose over-production and inadequate peripheral removal in the
postab- sorptive (fasting) hyperglycaemia of Type II (non-in- sulin dependent) diabetes mellitus
has produced di- verse estimates. Some studies show that a strong cor- relation exists ... Cited by 12 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org R Basu, A Basu, CM Johnson, WF Schwenk, RA Rizza - Diabetes, 2004 - Am Diabetes Assoc To determine whether the insulin dose-response curves for suppression of endogenous glucose
production (EGP) and stimulation of splanchnic glucose uptake (SGU) differ in nondiabetic humans
and are abnormal in type 2 diabetes, 14 nondiabetic and 12 diabetic subjects were ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] M Mevorach, A Giacca, Y Aharon, M … - Journal of Clinical …, 1998 - pubmedcentral.nih.gov We examined the ability of an equivalent increase in circu- lating glucose concentrations to inhibit
endogenous glucose production (EGP) and to stimulate glucose metabolism in patients with
Type 2 diabetes mellitus (DM2). Somatostatin was infused in the presence of basal ... Cited by 74 - Related articles - BL Direct - All 10 versions
A Basu, A Caumo, F Bettini, A Gelisio, A Alzaid, C … - Diabetes, 1997 - Am Diabetes Assoc People with NIDDM are resistant to insulin. The present studies sought to determine whether
the ability of glucose to regulate its own metabolism in the presence of basal insulin concentrations
is impaired. To address this question, basal insulin concentrations were maintained ... Cited by 47 - Related articles - BL Direct - All 5 versions
