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Scholar Results 1 - 10 of about 101 related to Caron: The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1.... (0.15 sec) 

The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 …

- diabetesjournals.org
M Caron, M Auclair, C Vigouroux, M Glorian, … - Diabetes, 2001 - Am Diabetes Assoc
Protease inhibitors used in the treatment of HIV infection have been causally
associated with lipodystrophy and insulin resistance and were shown to alter
adipocyte differentiation in cultured cells. We aimed to delineate the ...
Cited by 237 - Related articles - BL Direct - All 5 versions

Suppression of preadipocyte differentiation and promotion of adipocyte death by HIV …

- jbc.org
P Dowell, C Flexner, PO Kwiterovich, MD … - Journal of Biological Chemistry, 2000 - ASBMB
Many human immunodeficiency virus (HIV)-infected patients taking combination
antiretroviral therapy that includes HIV protease inhibitors experience atrophy
of peripheral subcutaneous adipose tissue. We investigated the effects of ...
Cited by 186 - Related articles - BL Direct - All 6 versions

Association between altered expression of adipogenic factor SREBP1 in lipoatrophic adipose …

- mapleleafmedical.com [PDF] 
JP Bastard, M Caron, H Vidal, V Jan, M … - The Lancet, 2002 - Elsevier
Patients' fat contained a higher proportion of small adipocytes than control
fat, together with lower mRNA concentrations of the adipogenic differentiation
factors CCAAT-enhancer binding protein (C/EBP) β and α, peroxisome ...
Cited by 272 - Related articles - BL Direct - All 7 versions

Inhibition of adipocyte differentiation by HIV protease inhibitors


B Zhang, K MacNaul, D Szalkowski, Z Li, J … - Journal of Clinical Endocrinology & Metabolism, 1999 - Endocrine Soc
Patients with AIDS who are receiving therapy with HIV protease inhibitors have
been widely reported to be afflicted with a syndrome characterized by
lipodystrophy (fat redistribution favoring the accumulation of abdominal ...
Cited by 154 - Related articles - BL Direct - All 5 versions

The mechanism of insulin resistance caused by HIV protease inhibitor therapy

- sciencemag.org
H Murata, PW Hruz, M Mueckler - Journal of Biological Chemistry, 2000 - ASBMB
Retroviral protease inhibitors used as therapy for HIV-1 infection have been
causally associated with serious metabolic side effects, including peripheral
lipodystrophy, hyperlipidemia, insulin resistance, and in some cases, overt ...
Cited by 369 - Related articles - BL Direct - All 7 versions

HIV protease inhibitors block adipogenesis and increase lipolysis in vitro.


JM Lenhard, ES Furfine, RG Jain, O Ittoop, LA … - Antiviral research, 2000 - ncbi.nlm.nih.gov
AIDS therapies employing HIV protease inhibitors (PIs) are associated with
changes in fat metabolism. However, the cellular mechanisms affected by PIs are
not clear. Thus, the affects of PIs on adipocyte differentiation were ...
Cited by 140 - Related articles - All 4 versions

Some HIV protease inhibitors alter lamin A/C maturation and stability, SREBP-1 nuclear …


M Caron, M Auclair, H Sterlingot, M … - Aids, 2003 - journals.lww.com
Skip Navigation Links Home > November 21, 2003 - Volume 17 - Issue 17 > Some HIV
protease inhibitors alter lamin A/C maturation and... ... From the a INSERM U.
402, Faculté de Médecine Saint-Antoine, Paris, and b Laboratoire de ...
Cited by 103 - Related articles - BL Direct - All 5 versions

The HIV protease inhibitor nelfinavir induces insulin resistance and increases basal …

- diabetesjournals.org
A Rudich, S Vanounou, K Riesenberg, M Porat … - Diabetes, 2001 - Am Diabetes Assoc
HIV protease inhibitors (HPIs) are potent antiretroviral agents clinically used
in the management of HIV infection. Recently, HPI therapy has been linked to the
development of a metabolic syndrome in which adipocyte insulin resistance ...
Cited by 105 - Related articles - BL Direct - All 3 versions

Effects of antiretroviral drug combinations on the differentiation of adipocytes


R Roche, I Poizot-Martin, C Martin-El Yazidi, … - Aids, 2002 - journals.lww.com
Objective: Preadipocyte cell lines present a cell model with which to understand
the physiopathological mechanisms underlying lipodystrophy syndrome, a common
com- plication observed in patients treated with highly active ...
Cited by 60 - Related articles - BL Direct - All 6 versions

Subcutaneous adipocyte apoptosis in HIV-1 protease inhibitor-associated lipodystrophy


P Domingo, X Matias-Guiu, RM Pujol, E … - Aids, 1999 - journals.lww.com
Methods: Fourteen HIV-infected patients with HIV-1 protease inhibitor-associated
lipodystrophy had a biopsy of subcutaneous fat performed in the antero-lateral
aspect of the right leg. The samples were submitted for standard pathologic ...
Cited by 200 - Related articles - BL Direct - All 4 versions


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