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Scholar Results 1 - 10 of about 101 related to Nolte: The HIV protease inhibitor indinavir decreases insulin-and contraction-stimulated.... (0.12 sec) 

The HIV protease inhibitor indinavir decreases insulin-and contraction-stimulated glucose …

- diabetesjournals.org
LA Nolte, KE Yarasheski, K Kawanaka, J … - Diabetes, 2001 - Am Diabetes Assoc
In many patients with human immunodeficiency virus (HIV) treated with HIV
protease inhibitors, a complication develops that resembles abdominal obesity
syndrome, with insulin resistance and glucose intolerance that, in some ...
Cited by 74 - Related articles - BL Direct - All 5 versions

The HIV protease inhibitor nelfinavir induces insulin resistance and increases basal …

- diabetesjournals.org
A Rudich, S Vanounou, K Riesenberg, M Porat … - Diabetes, 2001 - Am Diabetes Assoc
HIV protease inhibitors (HPIs) are potent antiretroviral agents clinically used
in the management of HIV infection. Recently, HPI therapy has been linked to the
development of a metabolic syndrome in which adipocyte insulin resistance ...
Cited by 105 - Related articles - BL Direct - All 3 versions

The HIV-1 protease inhibitor indinavir impairs insulin signalling in HepG2 hepatoma cells


M Schütt, M Meier, M Meyer, J Klein, SP Aries … - Diabetologia, 2000 - Springer
Patients treated with human immunodeficiency vi- rus-1 (HIV-1) protease
inhibitors frequently develop IGT or diabetes [1]. The underlying cause seems to
be a protease inhibitor-induced insulin resistance [1]. We investigated ...
Cited by 43 - Related articles - BL Direct - All 3 versions

The mechanism of insulin resistance caused by HIV protease inhibitor therapy

- sciencemag.org
H Murata, PW Hruz, M Mueckler - Journal of Biological Chemistry, 2000 - ASBMB
Retroviral protease inhibitors used as therapy for HIV-1 infection have been
causally associated with serious metabolic side effects, including peripheral
lipodystrophy, hyperlipidemia, insulin resistance, and in some cases, overt ...
Cited by 369 - Related articles - BL Direct - All 7 versions

Indinavir induces acute and reversible peripheral insulin resistance in rats


PW Hruz, H Murata, H Qiu, M Mueckler - Diabetes, 2002 - Am Diabetes Assoc
The use of HIV protease inhibitors (PIs) has been associated with several
metabolic changes, including lipodystrophy, hyperlipidemia, and insulin
resistance. The etiology of these adverse effects remains unknown. PIs have ...
Cited by 76 - Related articles - BL Direct - All 4 versions

Indinavir inhibits the glucose transporter isoform Glut4 at physiologic concentrations


H Murata, PW Hruz, M Mueckler - Aids, 2002 - journals.lww.com
Objectives: To determine the relative sensitivities of glucose transporter
isoforms to the protease inhibitor indinavir and to determine the kinetic
mechanism of indinavir- mediated Glut4 isoform inhibition. Methods: The ...
Cited by 153 - Related articles - All 3 versions

The HIV protease inhibitor indinavir impairs sterol regulatory element-binding protein-1 …

- diabetesjournals.org
M Caron, M Auclair, C Vigouroux, M Glorian, … - Diabetes, 2001 - Am Diabetes Assoc
Protease inhibitors used in the treatment of HIV infection have been causally
associated with lipodystrophy and insulin resistance and were shown to alter
adipocyte differentiation in cultured cells. We aimed to delineate the ...
Cited by 237 - Related articles - BL Direct - All 5 versions

Prospective evaluation of the effect of initiating indinavir-based therapy on insulin sensitivity …


MP Dubé, H Edmondson-Melançon, D Qian, … - JAIDS Journal of Acquired Immune Deficiency …, 2001 - journals.lww.com
Skip Navigation Links Home > June 1, 2001 - Volume 27 - Issue 2 > Prospective
Evaluation of the Effect of Initiating Indinavir... ... Dubé, Michael P.;
Edmondson-Melançon, Hannah; Qian, Dajun; Aqeel, Rubina; Johnson, Debra; ...
Cited by 88 - Related articles - BL Direct - All 5 versions

The HIV protease inhibitor saquinavir impairs lipid metabolism and glucose transport in …

- endocrinology-journals.org [PDF] 
S Ranganathan, PA Kern - Journal of Endocrinology, 2002 - Soc Endocrinology
Treatment of HIV infection using protease inhibitors is frequently associated
with lipodystrophy and impaired lipid and glucose metabolism. We examined the
effect of saquinavir, one of the protease inhibitors, on lipid metab- olism ...
Cited by 40 - Related articles - BL Direct - All 3 versions

Lipodystrophy in HIV-1-positive patients is associated with insulin resistance in multiple …

- uva.nl [PDF] 
M van der Valk, PH Bisschop, JA Romijn, MT … - Aids, 2001 - journals.lww.com
From the a National AIDS Therapy Evaluation Center (NATEC) and Department of
Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center,
Amsterdam, the b Department of Endocrinology and Metabolism, Academic ...
Cited by 98 - Related articles - BL Direct - All 4 versions


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