RG Gerrity, R Natarajan, JL Nadler, T Kimsey - Diabetes, 2001 - Am Diabetes Assoc Patients with diabetes are at higher risk for atherosclerotic disease than nondiabetic individuals
with other comparable risk factors. Studies examining mechanisms underlying diabetes-accelerated
atherosclerosis have been limited ... Cited by 96 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org JL Dixon, JD Stoops, JL Parker, MH Laughlin, … - … , and vascular biology, 1999 - Am Heart Assoc Abstract—Diabetic patients typically have not only hyperglycemia but also dyslipidemia. Study of
the pathogenic components of the diabetic milieu and mechanisms of accelerated atherosclerosis is
hindered by inadequate animal ... Cited by 84 - Related articles - BL Direct - All 6 versions
R Natarajan, RG Gerrity, JL Gu, L Lanting, L Thomas, … - Diabetologia, 2002 - Springer Diabetes is associated with significantly accelerated rates of atherosclerotic and hypertensive
cardiovas- cular diseases. The cellular and molecular mecha- nisms are still not fully understood,
mainly due to the lack of animal ... Cited by 62 - Related articles - BL Direct - All 5 versions
T Johansen, HS Hansen, B Richelsen, R … - Comparative medicine, 2001 - ncbi.nlm.nih.gov The objective of the study reported here was to induce obesity in the female Göttingen minipig to
establish a model of the human metabolic syndrome. Nine- to ten-month-old female Göttingen minipigs
received a high-fat high-energy ... Cited by 23 - Related articles - BL Direct - All 2 versions
- ►nih.gov CB Renard, F Kramer, F Johansson, N … - Journal of Clinical …, 2004 - Am Soc Clin Investig Diabetes in humans accelerates cardiovascular disease caused by atherosclerosis. The relative
contributions of hyperglycemia and dyslipidemia to atherosclerosis in patients with diabetes are not
clear, largely because there is a ... Cited by 91 - Related articles - BL Direct - All 8 versions
- ►ahajournals.org P Reaven, S Merat, F Casanada, M Sutphin, … - … , and vascular biology, 1997 - Am Heart Assoc Abstract Investigations into the mechanisms by which diabetes accelerates atherosclerosis have been
hampered by the lack of suitable animal models. We hypothesized that streptozotocin-treated LDL
receptor-deficient mice would be a ... Cited by 66 - Related articles - BL Direct - All 5 versions
RD Boullion, EA Mokelke, BR Wamhoff, CR Otis, … - Comparative …, 2003 - ncbi.nlm.nih.gov A weakness of many animal models of diabetes mellitus is the failure to use insulin therapy, which
typically results in severe body wasting. Data collected from such studies must be interpreted
cautiously to separate the effects ... Cited by 25 - Related articles - BL Direct - All 2 versions
LA Suzuki, M Poot, RG Gerrity, KE Bornfeldt - Diabetes, 2001 - Am Diabetes Assoc In combination with other factors, hyperglycemia may cause the accelerated progression of
atherosclerosis in people with diabetes. Arterial smooth muscle cell (SMC) proliferation and
accumulation contribute to ... Cited by 119 - Related articles - BL Direct - All 5 versions
RW Phillips, LM Panepinto, R Spangler, N … - Diabetes, 1982 - ncbi.nlm.nih.gov Two lines of Yucatan miniature swine have been developed by genetic selection for decreased and
increased glucose clearance during an iv glucose tolerance test. The decreased glucose clearance is
due to low peripheral insulin ... Cited by 22 - Related articles
- ►jlr.org JL Dixon, S Shen, JP Vuchetich, E Wysocka, GY … - The Journal of Lipid …, 2002 - ASBMB Male Yucatan swine were allocated to four groups (n = 5–6 pigs per group): low fat (3%) fed
control, high fat/2% cholesterol (CH) fed (HF), high fat/CH fed with alloxan-induced diabetes (DF)
and DF pigs that were treated with ... Cited by 25 - Related articles - BL Direct - All 5 versions
