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Scholar Results 1 - 10 of about 101 related to Embury: Proteins linked to a protein transduction domain efficiently transduce pancreatic islets. (0.09 sec) 

Proteins linked to a protein transduction domain efficiently transduce pancreatic islets

- diabetesjournals.org
J Embury, D Klein, A Pileggi, M Ribeiro, S … - Diabetes, 2001 - Am Diabetes Assoc
The resounding success of a new immunosuppressive regimen known as the Edmonton
protocol demonstrates that islet cell transplantation is becoming a therapeutic
reality for diabetes. However, under the Edmonton protocol, a single donor ...
Cited by 74 - Related articles - BL Direct - All 4 versions

Rapid Publication

- diabetesresearch.org [PDF] 
ETP Islets - DIABETES, 2001 - Am Diabetes Assoc
The resounding success of a new immunosuppressive regimen known as the Edmonton
protocol demonstrates that islet cell transplantation is becoming a therapeutic
reality for diabetes. However, under the Edmonton pro- tocol, a single ...
Related articles - All 2 versions

Protection of Islets by in SituPeptide-mediated Transduction of the IκB Kinase Inhibitor …


KK Rehman, S Bertera, R Bottino, AN … - Journal of Biological Chemistry, 2003 - ASBMB
We have previously demonstrated that adenoviral gene transfer of the NF-κB
inhibitor IκB to human islets results in protection from interleukin
(IL)-1β-mediated dysfunction and apoptosis. Here we report that human and ...
Cited by 53 - Related articles - BL Direct - All 4 versions

Characterization of a class of cationic peptides able to facilitate efficient protein transduction …


Z Mi, J Mai, X Lu, PD Robbins - Molecular Therapy, 2000 - Elsevier
Protein transduction domains (PTDs), such as the third helix of the Drosophila
Antennapedia homeobox gene (Antp) and the HIV TAT PTD, posses a characteristic
positive charge on the basis of their enrichment for arginine and lysine ...
Cited by 119 - Related articles - All 5 versions

Transduction of Cu, Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic …


HY Kwon, WS Eum, HW Jang, JH Kang, J Ryu, … - FEBS letters, 2000 - Elsevier
A human Cu,Zn-superoxide dismutase (Cu,Zn-SOD) gene was fused with a gene
fragment encoding the nine amino acid transactivator of transcription (Tat)
protein transduction domain (RKKRRQRRR) of HIV-1 in a bacterial expression ...
Cited by 81 - Related articles - All 6 versions

Heme oxygenase-1 fused to a TAT peptide transduces and protects pancreatic β-cells

- diabetesresearch.org [PDF] 
MM Ribeiro, D Klein, A Pileggi, R Damaris … - Biochemical and Biophysical Research …, 2003 - Elsevier
Transplantation of islets is becoming an established method for treating type 1
diabetes. However, viability of islets is greatly affected by necrosis/apoptosis
induced by oxidative stress and other insults during isolation and ...
Cited by 44 - Related articles - All 6 versions

Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets …

- diabetesjournals.org [PDF] 
N Giannoukakis, WA Rudert, SC Ghivizzani, A … - Diabetes, 1999 - Am Diabetes Assoc
Page 1. 1730 DIABETES, VOL. 48, SEPTEMBER 1999 Adenoviral Gene Transfer of
the Interleukin-1 Receptor Antagonist Protein to Human Islets ...
Cited by 97 - Related articles - All 4 versions

Standardization of Procedure for Efficient Ex Vivo Gene Transfer Into Porcine Pancreatic …


PY Benhamou, C Moriscot, P Prevost, E … - Transplantation, 1997 - journals.lww.com
Background. New strategies to improve the outcome of encapsulated porcine islet
transplantation may involve the transfer of gene sequences affecting islet
viability. While adenoviral vectors appear as the most efficient gene ...
Cited by 26 - Related articles - BL Direct - All 3 versions

Suppression of transmitter release by Tat HPC-1/syntaxin 1A fusion protein


T Fujiwara, T Yamamori, K Akagawa - BBA-Molecular Cell Research, 2001 - Elsevier
It has been reported that the fusion protein with the protein transduction
domain (PTD) peptide of HIV-1 Tat protein can be internalized through the cell
membrane of intact cells, although the exact mechanism is unknown. In this ...
Cited by 14 - Related articles - All 3 versions

Heparin binding by the HIV-1 tat protein transduction domain


S Hakansson, A Jacobs, M Caffrey - Protein Science: A Publication of the Protein Society, 2001 - pubmedcentral.nih.gov
The protein transduction domain from the HIV-1 tat protein (termed PTD-tat) has
been fused to the C-terminus of a model cargo protein, the IgG binding domain of
streptococcal protein G. We demonstrate that PG-Ctat (PTD-tat fused to the ...
Cited by 27 - Related articles - BL Direct - All 5 versions


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