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Scholar Results 1 - 10 of about 101 related to Burcelin: Glucose competence of the hepatoportal vein sensor requires the presence of an.... (0.15 sec) 

Glucose competence of the hepatoportal vein sensor requires the presence of an activated …

- glucagon.com [PDF] 
R Burcelin, A Da Costa, D Drucker, B Thorens - Diabetes, 2001 - Am Diabetes Assoc
Activation of the hepatoportal glucose sensors by portal glucose infusion leads
to increased glucose clearance and induction of hypoglycemia. Here, we
investigated whether glucagon-like peptide-1 (GLP-1) could modulate the ...
Cited by 127 - Related articles - BL Direct - All 8 versions

Portal GLP-1 administration in rats augments the insulin response to glucose via neuronal …

- physiology.org
B Balkan, X Li - … Journal of Physiology- Regulatory, Integrative and …, 2000 - Am Physiological Soc
The incretin glucagon-like peptide-1 (GLP-1)-(7---36) amide is an important
factor in prandial glucose homeostasis. Findings that GLP-1 is rapidly
inactivated led to the hypothesis that the target of GLP-1 is close to the ...
Cited by 77 - Related articles - BL Direct - All 5 versions

Vagal hepatopancreatic reflex effect evoked by intraportal appearance of tGLP-1


H Nakabayashi, M Nishizawa, A Nakagawa, R … - American Journal of Physiology- Endocrinology And …, 1996 - Am Physiological Soc
AN INCREASE IN PLASMA insulin level in response to Oral glucose administration
is much greater than that to intravenous glucose administration, where plasma
glu- cose levels are equivalent in both routes of glucose administration ...
Cited by 85 - Related articles - BL Direct - All 4 versions

Portal glucose infusion in the mouse induces hypoglycemia: evidence that the hepatoportal …

- diabetesjournals.org [PDF] 
R Burcelin, W Dolci, B Thorens - Diabetes, 2000 - Am Diabetes Assoc
To analyze the role of the murine hepatoportal glucose sensor in the control of
whole-body glucose metabo- lism, we infused glucose at a rate corresponding to
the endogenous glucose production rate through the portal vein of conscious ...
Cited by 74 - Related articles - BL Direct - All 6 versions

Synergistic effect of portal glucose and glucagon-like peptide-1 to lower systemic glucose …


V Ionut, K Hucking, IF Liberty, RN Bergman - Diabetologia, 2005 - Springer
Abstract Aims: Glucagon-like peptide-1 (GLP-1) is an insulinotropic hormone
released from the gut in response to nutrients. Besides its well-established
direct effect on pan- creatic beta cells, GLP-1 may also act by activating ...
Cited by 33 - Related articles - All 4 versions

Effect of intraportal glucagon-like peptide-1 on glucose metabolism in conscious dogs

- physiology.org
M Nishizawa, MC Moore, M Shiota, SM … - American Journal of Physiology- Endocrinology And …, 2003 - Am Physiological Soc
Arteriovenous difference and tracer ([3- 3 H]glucose) techniques were used in
42-h-fasted conscious dogs to identify any insulin-like effects of intraportally
administered glucagon-like peptide 1-(7-36)amide (GLP-1). Each study ...
Cited by 38 - Related articles - BL Direct - All 4 versions

Glucose sensing by the hepatoportal sensor is GLUT2-dependent: in vivo analysis in GLUT2 …

- diabetesjournals.org [PDF] 
R Burcelin, W Dolci, B Thorens - Diabetes, 2000 - Am Diabetes Assoc
In the preceding article, we demonstrated that activation of the hepatoportal
glucose sensor led to a paradoxical development of hypoglycemia that was
associated with increased glucose utilization by a subset of tissues. In ...
Cited by 90 - Related articles - BL Direct - All 5 versions

The hepatic vagal reception of intraportal GLP-1 is via receptor different from the pancreatic …


M Nishizawa, H Nakabayashi, K Kawai, T Ito, … - Journal of the autonomic nervous system, 2000 - Elsevier
Glucagon-like peptide-1 (7–36)amide (tGLP-1), a representative humoral
incretin, released into the portal circulation in response to a meal ingestion,
exerts insulinotropic action through binding to the tGLP-1 receptor known ...
Cited by 61 - Related articles - All 4 versions

Insulin-independent effects of GLP-1 on canine liver glucose metabolism: duration of …

- physiology.org
D Dardevet, MC Moore, D Neal, CA … - American Journal of Physiology- Endocrinology And …, 2004 - Am Physiological Soc
Whether glucagon-like peptide-1 (GLP-1) has insulin-independent effects on
glucose disposal in vivo was assessed in conscious dogs by use of tracer and
arteriovenous difference techniques. After a basal period, each experiment ...
Cited by 32 - Related articles - All 3 versions

GLUT4, AMP kinase, but not the insulin receptor, are required for hepatoportal glucose sensor …

- nih.gov
R Burcelin, V Crivelli, C Perrin, A Da Costa … - Journal of Clinical Investigation, 2003 - Am Soc Clin Investig
Recent evidence suggests the existence of a hepatoportal vein glucose sensor,
whose activation leads to enhanced glucose use in skeletal muscle, heart, and
brown adipose tissue. The mechanism leading to this increase in whole body ...
Cited by 45 - Related articles - BL Direct - All 8 versions


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