J Westerlund, P Bergsten - Diabetes, 2001 - Am Diabetes Assoc The effects of metabolic inhibition on insulin release and the cytoplasmic Ca 2+ concentration
([Ca 2+ ] i ) were studied in individually perifused pancreatic islets from ob/ob mice. The modest
basal secretion in the presence of 3 mmol/l glucose was pulsatile with a frequency of ... Cited by 14 - Related articles - BL Direct - All 5 versions
PA Smith, P Proks, FM Ashcroft - The Journal of Physiology, 1999 - Physiological Soc A combination of patch-clamp, amperometric and fluorimetric methods were used to investigate
the Ca 2+ dependence and kinetics of secretion from pancreatic β-cells elicited by voltage-gated
Ca 2+ entry. ... Whether measured by the change in cell capacitance or by amperometric ... Cited by 16 - Related articles - All 6 versions
MJ Dunne - Diabetic Medicine, 2000 - ingentaconnect.com In 1968, reports of the ®rst microelectrode recordings of insulin-secreting cells were
published. Thirty years later it is now established that electrical responses of b-cells play a critical
role in stimulus-secretion coupling. It is now also clear that defects in ion channel genes ... Cited by 5 - Related articles - All 4 versions
- ►jbc.org L Juntti-Berggren, DL Webb, POG Arkhammar, V … - Journal of Biological …, 2003 - ASBMB Glucose stimulation of pancreatic -cells causes oscillatory influx of Ca 2+ , leading to pulsatile
insulin secretion. We have proposed that this is due to oscillations of glycolysis and the
ATP/ADP ratio, which modulate the activity of ATP-sensitive K + channels. We show here ... Cited by 16 - Related articles - BL Direct - All 4 versions
Y Hamada, H Ikegami, H Ueda, Y Kawaguchi, E … - Metabolism, 2001 - Elsevier To clarify the mechanisms of impaired insulin secretion in Nagoya-Shibata-Yasuda (NSY)
mice, an inbred strain of mice with spontaneous development of type 2 (non[ndash
]insulin-dependent) diabetes mellitus, the insulin response to glucose (5.5 to 27.8 ... Cited by 7 - Related articles - BL Direct - All 6 versions
J Westerlund, BA Wolf, P Bergsten - Diabetes, 2002 - Am Diabetes Assoc An insulin-mimetic compound (L-783,281) was used in an attempt to determine the role of the
β-cell insulin receptor (IR) on insulin release. Islets were isolated from C57Bl/6j mice and cultured
for 1 to 4 days. Insulin release from individual islets perifused in the presence of 3 mmol/l ... Cited by 8 - Related articles - BL Direct - All 5 versions
