- ►diabetesjournals.org A Gastaldelli, E Toschi, M Pettiti, S Frascerra … - Diabetes, 2001 - Am Diabetes Assoc Gluconeogenesis (GNG) is enhanced in type 2 diabetes. In experimental animals,
insulin at high doses decreases the incorporation of labeled GNG precursors into
plasma glucose. Whether physiological hyperinsulinemia has any effect on ... Cited by 63 - Related articles - BL Direct - All 5 versions
A Adkins, R Basu, M Persson, B Dicke, P … - Diabetes, 2003 - Am Diabetes Assoc To determine the mechanism(s) by which insulin inhibits endogenous glucose
production (EGP) in nondiabetic humans, insulin was infused at rates of 0.25,
0.375, or 0.5 mU · kg −1 · min −1 and glucose was clamped at ∼5.5 ... Cited by 30 - Related articles - BL Direct - All 4 versions
DS Edgerton, S Cardin, M Emshwiller, D … - Diabetes, 2001 - Am Diabetes Assoc Based on our earlier work, a 2.5-fold increase in insulin secretion should
completely inhibit hepatic glucose production through the hormone's direct
effect on hepatic glycogen metabolism. The aim of the present study was to ... Cited by 67 - Related articles - BL Direct - All 5 versions
WC Schumann, A Gastaldelli, V Chandramouli, … - Analytical Biochemistry, 2001 - Elsevier 4. M. Roden, H. Stingl, V. Chandramouli, WC Schumann, A. Hofer, BR Landau, P.
Nowotny, W. Waldhausl and GI Shulman, Effects of free fatty acids elevation on
postabsorptive endogenous glucose production and gluconeogenesis in man. ... Cited by 30 - Related articles - BL Direct - All 3 versions
- ►physiology.org G Boden, X Chen, TP Stein - American Journal of Physiology- Endocrinology And …, 2001 - Am Physiological Soc We tested the generally accepted concept that increased gluconeogenesis (GNG)
and endogenous glucose production (EGP) are the main reasons for postabsorptive
hyperglycemia in patients with type 2 diabetes mellitus (T2DM). GNG was ... Cited by 76 - Related articles - BL Direct - All 3 versions
- ►physiology.org G Boden, P Cheung, TP Stein, K Kresge, M … - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc Free fatty acids (FFA) have been shown to inhibit insulin suppression of
endogenous glucose production (EGP). To determine whether this is the result of
stimulation by FFA of gluconeogenesis (GNG) or glycogenolysis (GL) or a ... Cited by 120 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] A Gastaldelli, S Baldi, M Pettiti, E Toschi, S … - Diabetes, 2000 - Am Diabetes Assoc The contribution of gluconeogenesis (GNG) to endoge- nous glucose output (EGO)
in type 2 diabetes is con- troversial. Little information is available on the
sepa- rate influence of obesity on GNG. We measured percent GNG (by the ... Cited by 133 - Related articles - BL Direct - All 5 versions
G Perriello, S Pampanelli, P Del Sindaco, C … - Diabetes, 1997 - Am Diabetes Assoc To assess the mechanisms of fasting hyperglycemia in NIDDM patients with mild
elevation of fasting plasma glucose (FPG) compared with NIDDM patients with
overt hyperglycemia, we studied 29 patients with NIDDM, who were divided in ... Cited by 42 - Related articles - BL Direct - All 4 versions
A Basu, A Caumo, F Bettini, A Gelisio, A … - Diabetes, 1997 - Am Diabetes Assoc People with NIDDM are resistant to insulin. The present studies sought to
determine whether the ability of glucose to regulate its own metabolism in the
presence of basal insulin concentrations is impaired. To address this ... Cited by 47 - Related articles - BL Direct - All 5 versions
A Wajngot, V Chandramouli, WC Schumann, K … - Metabolism, 2001 - Elsevier Contributions of gluconeogenesis to glucose production were determined between
14 to 22 hours into a fast in type 2 diabetics (n = 9) and age-weight-matched
controls (n = 7); ages, 60.4 ± 2.3 versus 55.6 ± 1.2 years and body mass ... Cited by 48 - Related articles - BL Direct - All 6 versions
