DS Edgerton, S Cardin, M Emshwiller, D … - Diabetes, 2001 - Am Diabetes Assoc Based on our earlier work, a 2.5-fold increase in insulin secretion should
completely inhibit hepatic glucose production through the hormone's direct
effect on hepatic glycogen metabolism. The aim of the present study was to ... Cited by 67 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org A Gastaldelli, E Toschi, M Pettiti, S Frascerra … - Diabetes, 2001 - Am Diabetes Assoc Gluconeogenesis (GNG) is enhanced in type 2 diabetes. In experimental animals,
insulin at high doses decreases the incorporation of labeled GNG precursors into
plasma glucose. Whether physiological hyperinsulinemia has any effect on ... Cited by 63 - Related articles - BL Direct - All 5 versions
WC Schumann, A Gastaldelli, V Chandramouli, … - Analytical Biochemistry, 2001 - Elsevier 4. M. Roden, H. Stingl, V. Chandramouli, WC Schumann, A. Hofer, BR Landau, P.
Nowotny, W. Waldhausl and GI Shulman, Effects of free fatty acids elevation on
postabsorptive endogenous glucose production and gluconeogenesis in man. ... Cited by 30 - Related articles - BL Direct - All 3 versions
- ►physiology.org G Boden, X Chen, TP Stein - American Journal of Physiology- Endocrinology And …, 2001 - Am Physiological Soc We tested the generally accepted concept that increased gluconeogenesis (GNG)
and endogenous glucose production (EGP) are the main reasons for postabsorptive
hyperglycemia in patients with type 2 diabetes mellitus (T2DM). GNG was ... Cited by 76 - Related articles - BL Direct - All 3 versions
A Adkins, R Basu, M Persson, B Dicke, P … - Diabetes, 2003 - Am Diabetes Assoc To determine the mechanism(s) by which insulin inhibits endogenous glucose
production (EGP) in nondiabetic humans, insulin was infused at rates of 0.25,
0.375, or 0.5 mU · kg −1 · min −1 and glucose was clamped at ∼5.5 ... Cited by 30 - Related articles - BL Direct - All 4 versions
- ►physiology.org G Boden, P Cheung, TP Stein, K Kresge, M … - American Journal of Physiology- Endocrinology And …, 2002 - Am Physiological Soc Free fatty acids (FFA) have been shown to inhibit insulin suppression of
endogenous glucose production (EGP). To determine whether this is the result of
stimulation by FFA of gluconeogenesis (GNG) or glycogenolysis (GL) or a ... Cited by 121 - Related articles - BL Direct - All 5 versions
- ►physiology.org V Chandramouli, K Ekberg, WC Schumann, … - American Journal of Physiology- Endocrinology And …, 1997 - Am Physiological Soc The use of 2 H 2 O in estimating gluconeogenesis' contribution to glucose
production (%GNG) was examined during progressive fasting in three groups of
healthy subjects. One group (n = 3) ingested 2 H 2 O to a body water ... Cited by 85 - Related articles - BL Direct - All 4 versions
- ►nih.gov [PDF] BR Landau, J Wahren, V Chandramouli, WC … - Journal of Clinical Investigation, 1996 - pubmedcentral.nih.gov Healthy subjects ingested 2H2O and after 14, 22, and 42 h of fasting the
enrichments of deuterium in the hydrogens bound to carbons 2, 5, and 6 of blood
glucose and in body water were determined. The hydrogens bound to the car- ... Cited by 219 - Related articles - All 8 versions
DK Sindelar, JH Balcom, CA Chu, DW Neal, … - Diabetes, 1996 - Am Diabetes Assoc We investigated the mechanisms by which peripheral or portal insulin can
independently alter liver glucose production. Isotopic ([3-3H]glucose) and
arteriovenous difference methods were used in conscious overnight-fasted ... Cited by 80 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org [PDF] A Gastaldelli, S Baldi, M Pettiti, E Toschi, S … - Diabetes, 2000 - Am Diabetes Assoc The contribution of gluconeogenesis (GNG) to endoge- nous glucose output (EGO)
in type 2 diabetes is con- troversial. Little information is available on the
sepa- rate influence of obesity on GNG. We measured percent GNG (by the ... Cited by 133 - Related articles - BL Direct - All 5 versions
