A Takano, T Haruta, M Iwata, I Usui, T Uno, … - Diabetes, 2001 - Am Diabetes Assoc Growth hormone (GH) is well known to induce in vivo insulin resistance. However,
the molecular mechanism of GH-induced cellular insulin resistance is largely
unknown. In this study, we demonstrated that chronic GH treatment of ... Cited by 54 - Related articles - BL Direct - All 4 versions
- ►physiology.org [PDF] TR Smith, JS Elmendorf, TS David, J Turinsky - American Journal of Physiology- Endocrinology And …, 1997 - Am Physiological Soc GLUT-4. Am. J. Physiol. 272 (EndocrinoZ. Metab. 35): E1071-
E1079,1997.-Treatment of rats with growth hormone (GH; 1 mg/kg SC) twice daily
over 2.5 days did not alter fasting plasma glucose or glucose tolerance but ... Cited by 71 - Related articles - BL Direct - All 3 versions
- ►ebmonline.org FP Dominici, D Turyn - Experimental Biology and Medicine, 2002 - SEBM Growth hormone (GH) counteracts insulin action on lipid and glucose metabolism.
However, the sequence of molecular events leading to these changes is poorly
understood. Insulin action is initiated by binding of the hormone to its ... Cited by 63 - Related articles - BL Direct - All 4 versions
ACP Thirone, CRO Carvalho, SL Brenelli, LA … - Molecular and cellular endocrinology, 1997 - Elsevier Growth hormone (GH) is known to produce insulin resistance, but the exact
molecular mechanism remains unclear. We have chronically treated rats with GH
and observed that the levels of insulin receptor in the liver or muscle ... Cited by 54 - Related articles - All 6 versions
M Fickova, S Zorad, L Macho - Hormone and metabolic research= Hormon-und …, 1997 - ncbi.nlm.nih.gov Daily ip administration of thyroxine (T4; 50 micrograms/100 g BW) to adult male
rats for one week doubled the thyroxinemia and induced significant augmentation
of glycemia and insulinemia. Hyperthyroxinemia was also manifested by ... Cited by 12 - Related articles - BL Direct - All 3 versions
- ►physiology.org FP Dominici, D Cifone, A Bartke, D Turyn - American Journal of Physiology- Endocrinology And …, 1999 - Am Physiological Soc Growth hormone (GH) excess is associated with insulin resistance, but the
molecular mechanisms of this association are poorly understood. In the current
work, we have examined the consequences of exposure to high GH levels on ... Cited by 48 - Related articles - All 3 versions
- ►endocrinology-journals.org [PDF] FP Dominici, A Balbis, A Bartke, D Turyn - Journal of Endocrinology, 1998 - Soc Endocrinology Overexpression of bovine growth hormone (bGH) in transgenic (PEPCK-bGH) mice
induces resistance to insulin, which is compensated by a major increase in
insulin levels. In these animals, hepatic insulin receptors (InsRs) are ... Cited by 20 - Related articles - BL Direct - All 8 versions
- ►nih.gov A Takano, I Usui, T Haruta, J Kawahara, T … - Molecular and Cellular Biology, 2001 - Am Soc Microbiol A pathway sensitive to rapamycin, a selective inhibitor of mammalian target of
rapamycin (mTOR), down-regulates effects of insulin such as activation of Akt
(protein kinase B) via proteasomal degradation of insulin receptor ... Cited by 116 - Related articles - BL Direct - All 5 versions
[CITATION] Isoproterenol is a positive regulator of SOCS-3 gene expression in 3T3-L1 adipocytes
M Fasshauer, J Klein, U Lossner, R Paschke - Journal of Endocrinology, 2002 Cited by 3 - Related articles
SJ Frank - Growth Hormone & IGF Research, 2001 - Elsevier Growth hormone (GH) is a major growth-promoting and metabolic regulatory
hormone. Interaction of GH with its cell surface GH receptor (GHR), by virtue of
receptor dimerization, causes activation of the GHR-associated cytoplasmic ... Cited by 42 - Related articles - BL Direct - All 3 versions
