A Malhotra, BPS Kang, S Cheung, D Opawumi, LG … - Diabetes, 2001 - Am Diabetes Assoc Activation of the protein kinase C (PKC) family is a potential signaling mechanism by which high
ambient glucose concentration modulates the phenotype and physiological function of cells.
Recently, the cardiac renin angiotensin system (RAS) has been reported to promote PKC ... Cited by 62 - Related articles - BL Direct - All 5 versions
- ►physiology.org X Liu, J Wang, N Takeda, L Binaglia, V … - American Journal of …, 1999 - Am Physiological Soc To understand cardiac dysfunction in diabetes, the activity of protein kinase C (PKC) and protein
contents of its isozymes (PKC- , - , - , and - ) were examined in diabetic rats upon injection of
streptozotocin (65 mg/kg iv). The hearts were removed at 1, 2, 4, and 8 wk, and some of ... Cited by 46 - Related articles - BL Direct - All 3 versions
- ►uwyo.edu [PDF] AJ Davidoff, MB Davidson, MW Carmody, ME Davis … - Molecular and cellular …, 2004 - Springer Molecular and Cellular Biochemistry 262: 155–163, 2004. c 2004 Kluwer Academic
Publishers. Printed in the Netherlands. ... Amy J. Davidoff, 1 Michael B. Davidson, 1 Marybeth
W. Carmody, 1 ... Mari-Elena Davis 1 and Jun Ren 2 ... 1Department of Pharmacology, ... Cited by 26 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org A Malhotra, D Reich, D Reich, A Nakouzi, V … - Circulation …, 1997 - Am Heart Assoc Abstract A cardiomyopathy that is characterized by an impairment in diastolic relaxation and
a loss of calcium sensitivity of the isolated myofibril has been described in chronic diabetic animals
and humans. To explore a possible role for protein kinase C (PKC)–mediated ... Cited by 102 - Related articles - BL Direct - All 5 versions
- ►physiology.org T Ishikawa, H Kajiwara, S Kurihara - American Journal of …, 1999 - Am Physiological Soc The mechanisms of the slower time courses of Ca 2+ transients (CaT) and contraction in diabetic
(diabetes mellitus, DM) myocardium were studied. The aequorin method was applied to papillary
muscles of streptozotocin-induced DM and control rats. The time courses of CaT and ... Cited by 44 - Related articles - BL Direct - All 3 versions
Y Shimoni - The Journal of Physiology, 1999 - Physiological Soc In control myocytes, two calcium-independent outward K + currents, the transient I t and the sustained
I ss , were attenuated by 18.9 ± 2.0 and 16.8 ± 3.5%, respectively (mean ±sem), following addition
of a synthetic analogue of diacylglycerol, DiC8 (20 μm). In myocytes from hypothyroid or ... Cited by 30 - Related articles - BL Direct - All 8 versions
T Ha, G Kotsanas, I Wendt - Clinical and Experimental Pharmacology … - interscience.wiley.com 1. The contractile function of diabetic hearts is impaired. In addition, the responsiveness of diabetic
cardiac muscle to sympathetic stimulation is altered. Previous studies have revealed a depressed
response to β-adrenoceptor stimulation; however, the response to α-adrenoceptor ... Cited by 13 - Related articles - BL Direct - All 3 versions
- ►ahajournals.org Y Takeishi, T Jalili, NA Ball, RA Walsh - Circulation research, 1999 - Am Heart Assoc Abstract—Currently at least 11 protein kinase C (PKC) isoforms have been identified and may
play different roles in cell signaling pathways leading to changes in cardiac contractility, the hypertrophic
response, and tolerance to myocardial ischemia. The purpose of the present study was to ... Cited by 98 - Related articles - BL Direct - All 5 versions
J Krützfeldt, W Raasch, HH Klein - Naunyn-Schmiedeberg's Archives of …, 2000 - Springer Abstract To investigate mechanisms by which angio- tensin converting enzyme (ACE)-inhibition
increases in- sulin sensitivity, spontaneously hypertensive (SH) rats were treated with or without
ramipril (1 mg/kg per day) for 12 weeks. Insulin binding and protein levels of insulin ... Cited by 16 - Related articles - BL Direct - All 2 versions
