- ►chiroonline.net [PDF] RA Kowluru, J Tang, TS Kern - Diabetes, 2001 - Am Diabetes Assoc Antioxidants were administered to diabetic rats and experimentally galactosemic
rats to evaluate the ability of these agents to inhibit the development of
diabetic retinopathy. Alloxan diabetic rats and nondiabetic rats that were ... Cited by 146 - Related articles - BL Direct - All 6 versions
RA Kowluru, TS Kern, RL Engerman - Free Radical Biology and Medicine, 1996 - Elsevier Activities of enzymes that protect the retina from reactive oxygen species were
investigated in experimentally diabetic rats and experimentally galactosemic
rats, two animal models known to develop vascular lesions consistent with ... Cited by 93 - Related articles - BL Direct - All 5 versions
- ►iovs.org TS Kern, J Tang, M Mizutani, RA Kowluru, RH … - Investigative ophthalmology & visual science, 2000 - ARVO METHODS. Rats with alloxan-induced diabetes and rats fed a 30% galactose diet
(known to induce diabetic-like retinopathy) were assigned randomly to receive
diet with (2.5 g/kg diet) or without AMG. After 6 to 8 months of diabetes ... Cited by 126 - Related articles - BL Direct - All 4 versions
RA Kowluru, P Koppolu, S Chakrabarti, S … - Free radical research, 2003 - informahealthcare.com Oxidative stress is increased in the retina in diabetes, and long-term
administration of antioxidants inhibits the development of retinopathy in
diabetic rats. The purpose of this study is to determine how diabetes ... Cited by 75 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org RA Kowluru, S Odenbach - Diabetes, 2004 - Am Diabetes Assoc Oxidative stress is increased in the retina in diabetes, and it is considered to
play an important role in the development of retinopathy. α-Lipoic acid, a
thiol antioxidant, has been shown to have beneficial effects on ... Cited by 74 - Related articles - BL Direct - All 6 versions
W Li, M Yanoff, B Jian, Z He - Cellular and molecular biology (Noisy-le-Grand, France …, 1999 - ncbi.nlm.nih.gov Because programmed cell death (PCD) is an important mode of pericyte dropout in
human diabetic retinopathy, whether increased oxidative stress in cells with
diminished antioxidant defenses plays a causative role in the PCD process ... Cited by 48 - Related articles - BL Direct - All 2 versions
Y Du, MA Smith, CM Miller, TS Kern - Journal of neurochemistry, 2002 - interscience.wiley.com Aminoguanidine inhibits the development of retinopathy in diabetic animals, but
the mechanism remains unclear. Inasmuch as aminoguanidine is a relatively
selective inhibitor of the inducible isoform of nitric oxide synthase ... Cited by 83 - Related articles - BL Direct - All 5 versions
RA Kowluru, P Koppolu - Free Radical Research, 2002 - informahealthcare.com Apoptosis of retinal endothelial cells and pericytes is postulated to contribute
to the development of retinopathy in diabetes. The goal of this study is to
investigate diabetes- induced activation of retinal caspase-3, an apoptosis ... Cited by 60 - Related articles - BL Direct - All 7 versions
- ►iovs.org RA Kowluru, SN Abbas - Investigative ophthalmology & visual science, 2003 - ARVO METHODS. Mitochondria and cytosol fractions were prepared from retina of rats
with streptozotocin-induced diabetes and from the isolated retinal endothelial
cells and pericytes incubated in 5 or 20 mM glucose medium for up to 10 ... Cited by 52 - Related articles - BL Direct - All 4 versions
RA Kowluru - Diabetes, 2003 - Am Diabetes Assoc Clinical and experimental studies have shown that reinstitution of good glycemic
control (GC) after a period of poor glycemic control (PC) does not produce
immediate benefits on the progression of retinopathy, and hyperglycemia is ... Cited by 61 - Related articles - BL Direct - All 9 versions
