T Shike, S Hirose, M Kobayashi, K Funabiki, T … - Diabetes, 2001 - Am Diabetes Assoc The KK/Ta mouse strain serves as a suitable polygenic model for human type 2
diabetes. Using 93 microsatellite markers in 208 KK/Ta × (BALB/c × KK/Ta)F1
male backcross mice, we carried out a genome-wide linkage analysis of KK/Ta ... Cited by 36 - Related articles - BL Direct - All 4 versions
H Ikeda - Diabetes research and clinical practice, 1994 - cat.inist.fr KK mouse. H IKEDA Diabetes research and clinical practice 24:OCTOCT,
313-316, Elsevier Science, 1994. Anomalie tolérance glucose ... Cited by 28 - Related articles - All 3 versions
S Taketomi, H Ikeda, E Ishikawa, H Iwatsuka - Horm Metab Res, 1982 - thieme-connect.com A convenient method for determining the overall insulin sensitivity of small
animals was established based on the steady state plasma glucose (SSPG)
concentration method of Shen, Reaven and Farguhar (1970). Subcutaneous ... Cited by 11 - Related articles - All 2 versions
- ►diabetesjournals.org M Kobayashi, T Ohno, A Tsuji, M Nishimura, F … - Diabetes, 2003 - Am Diabetes Assoc Type 2 diabetes in humans is not a single gene disorder but a multifactorial
disease caused by the interaction of multiple genes and environmental factors.
Recombinant inbred (RI) strains are a powerful tool for analyzing not only ... Cited by 17 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org T Gohda, Y Makita, T Shike, M Tanimoto, K … - Diabetes, 2003 - Am Diabetes Assoc The KK/Ta strain serves as a suitable polygenic mouse model for the common form
of type 2 diabetes associated with obesity in humans. Recently, we reported the
susceptibility loci contributing to type 2 diabetes and related phenotypes ... Cited by 39 - Related articles - BL Direct - All 4 versions
T Matsuo, A Shino - Diabetologia, 1972 - Springer Summary. The effect of goldthioglueose (GTG) obesity on development of diabetes
was investigated in geneti- cally diabetic (KK) and normal (ICR and C57BL) mice.
GTG obesity intensified diabetic traits in KK mice from chemical diabetes ... Cited by 24 - Related articles - All 2 versions
- ►tokushima-u.ac.jp [PDF] S Takeshita, M Moritani, K Kunika, H Inoue, M … - Mammalian Genome, 2006 - Springer Abstract To identify novel genetic modifiers of type 2 dia- betes (T2D), we
performed quantitative trait loci (QTL) analysis on F 2 progeny of
hypoinsulinemic diabetic Akita mice, heterozygous for the Ins2 gene ... Cited by 8 - Related articles - BL Direct - All 5 versions
S Taketomi, T Fujita, K Yokono - Diabetes research and clinical practice, 1988 - ncbi.nlm.nih.gov Alterations of the insulin receptor and of glucose metabolism were examined in
adipocytes from genetically diabetic KK mice. Compared with those from control
C57BL/6 mice, adipocytes from KK mice showed weaker insulin binding and ... Cited by 8 - Related articles - All 2 versions
- ►diabetesjournals.org [PDF] H Ueda, H Ikegami, Y Kawaguchi, T Fujisawa, … - Diabetes, 1999 - Am Diabetes Assoc Type 2 diabetes is a complex trait with both genes and environmental factors
contributing to susceptibility. Except for rare subtypes with monogenic
inheritance, the genetic basis of type 2 diabetes is unknown because of the ... Cited by 46 - Related articles - BL Direct - All 4 versions
L Plum, K Giesen, R Kluge, E Junger, K … - Diabetologia, 2002 - Springer Aims/hypothesis. The diabetes susceptibility locus Nidd/SJL was identified in an
outcross of New Zealand obese (NZO) and lean Swiss/Jackson Laboratory mouse
strain (SJL) mice. Here we characterise its effects in a NZO × ... Cited by 28 - Related articles - BL Direct - All 4 versions
