K Filipsson, M Kvist-Reimer, B Ahrén - Diabetes, 2001 - Am Diabetes Assoc The neuropeptide pituitary adenylate cyclase–activating polypeptide (PACAP) is ubiquitously
distributed in both the central and peripheral nervous systems and exerts a variety of effects.
PACAP is a neuropeptide in pancreatic islets, where it has been suggested as a ... Cited by 47 - Related articles - BL Direct - All 5 versions
CA Polypeptide, I Function - DIABETES, 2001 - Am Diabetes Assoc The neuropeptide pituitary adenylate cyclase–activating polypeptide (PACAP) is ubiquitously
distributed in both the central and peripheral nervous systems and exerts a variety of effects.
PACAP is a neuropeptide in pancreatic islets, where it has been suggested as a ... Related articles
K Yamamoto, H Hashimoto, S Tomimoto, N Shintani, J … - Diabetes, 2003 - Am Diabetes Assoc Pituitary adenylate cyclase-activating polypeptide (PACAP), a member of the vasoactive intestinal
peptide/secretin/glucagon family, stimulates insulin secretion from islets in a glucose-dependent
manner at femtomolar concentrations. To assess PACAP's pancreatic function in vivo, we ... Cited by 37 - Related articles - BL Direct - All 4 versions
T Yada, M Sakurada, K Filipsson, M Kikuchi, B … - Annals of the New York …, 2000 - ncbi.nlm.nih.gov PACAP is an islet peptide that serves as an endogenous amplifier of glucose induced insulin
secretion. Furthermore, we has recently found that PACAP also potentiates insulin stimulated
glucose uptake in adipocytes. Therefore, an antidiabetic action of PACAP is possible. In ... Cited by 28 - Related articles - BL Direct - All 3 versions
K Filipsson, F Sundler, J Hannibal, B Ahren - Regulatory peptides, 1998 - ncbi.nlm.nih.gov We have studied the localization, receptor occupancy and potency of the neuropeptide pituitary
adenylate cyclase-activating polypeptide (PACAP) in insulin-producing tissues. Immunocytochemistry
showed that PACAP-like immunoreactivity (PACAP-IR) was localized to pancreatic ... Cited by 47 - Related articles - All 3 versions
GM Portela-Gomes, A Lukinius, O Ljungberg, S … - Regulatory …, 2003 - 万方数据资源系统 Pituitary adenylate cyclase-activating polypeptide (PACAP) is an islet neuropeptide with potent
insulinotropic action. The current study investigates PACAP expression in normal human and
rat pancreatic islets, and whether it is altered in diabetic state. To that end, PACAP ... Cited by 14 - Related articles - All 4 versions
N Shintani, S Tomimoto, H Hashimoto, C Kawaguchi, A … - Life Sciences, 2003 - Elsevier Pituitary adenylate cyclase-activating polypeptide (PACAP) is a pleiotropic neuropeptide implicated
in a broad variety of physiological processes. To assess PACAP's function in vivo, we recently
generated PACAP knockout mice (PACAP −/− ) and transgenic mice overexpressing ... Cited by 19 - Related articles - All 4 versions
- ►nih.gov F Jamen, K Persson, G Bertrand, N … - Journal of Clinical …, 2000 - Am Soc Clin Investig Pituitary adenylate cyclase–activating polypeptide (PACAP) is a ubiquitous neuropeptide of the
vasoactive intestinal peptide (VIP) family that potentiates glucose-stimulated insulin
secretion. Pancreatic β cells express two PACAP receptor subtypes, a PACAP-preferring ( ... Cited by 107 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org M Tsutsumi, TH Claus, Y Liang, Y Li, L Yang, J Zhu, F … - Diabetes, 2002 - Am Diabetes Assoc Pituitary adenylate cyclase—activating peptide (PACAP) and vasoactive intestinal peptide
(VIP) activate two shared receptors, VPAC1 and VPAC2. Activation of VPAC1 has been implicated
in elevating glucose output, whereas activation of VPAC2 may be involved in insulin ... Cited by 48 - Related articles - BL Direct - All 5 versions
M Nakata, S Shioda, Y Oka, I Maruyama, T Yada - Peptides, 1999 - 万方数据资源系统 Pituitary adenylate cyclase-activating polypeptide (PACAP) is localized in pancreatic nerve fibers
and islets and potently augments glucose-induced insulin secretion. The present study explored
a possible extra-pancreatic action of PACAP. The specific PACAP receptor (PAC1 ... Cited by 23 - Related articles - All 3 versions
