A Pileggi, RD Molano, T Berney, P Cattan, C Vizzardelli … - Diabetes, 2001 - Am Diabetes Assoc Transplantation of islets of Langerhans represents a viable therapeutic approach for the treatment
of type 1 diabetes. Unfortunately, transplanted islets are susceptible to allogeneic recognition
and rejection, recurrence of autoimmunity, and destruction by local inflammation at the ... Cited by 165 - Related articles - BL Direct - All 5 versions
E Tobiasch, L Günther, FH Bach - Journal of Investigative Medicine, 2001 - journals.lww.com Skip Navigation Links Home > November 2001 - Volume 49 - Issue 6 > Heme Oxygenase-1
Protects Pancreatic [beta] Cells From Apopt... ... Tobiasch, Edda; Günther, Lukas; Bach, Fritz
H. ... From the Immunobiology Research Center, Beth Israel Deaconess Medical Center, ... Cited by 79 - Related articles - All 4 versions
- ►endojournals.org J Ye, SG Laychock - Endocrinology, 1998 - Endocrine Soc Heme oxygenase (HO)-1 expression was investigated in rat isolated pancreatic islets. Freshly
isolated islets showed no evidence of HO-1 expression. After a 20-h culture, there was a small
increase in HO-1 in control islets, and interleukin-1ß (IL-1ß) induced HO-1 expression ... Cited by 74 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org R Bottino, AN Balamurugan, S Bertera, M Pietropaolo, … - Diabetes, 2002 - Am Diabetes Assoc The most commonly used technical approach to isolate human pancreatic islets intended for
allotransplants generates a product that is hampered by mechanical and chemical insults, which
dramatically reduce the mass of viable and functional transplantable cells. We tested a ... Cited by 79 - Related articles - BL Direct - All 5 versions
- ►diabetesresearch.org [PDF] MM Ribeiro, D Klein, A Pileggi, R Damaris Molano, … - … and Biophysical Research …, 2003 - Elsevier Transplantation of islets is becoming an established method for treating type 1 diabetes.
However, viability of islets is greatly affected by necrosis/apoptosis induced by oxidative stress
and other insults during isolation and subsequent in vitro culture. Expression of ... Cited by 44 - Related articles - All 6 versions
- ►diabetesjournals.org L Günther, PO Berberat, M Haga, S Brouard, RN Smith, … - Diabetes, 2002 - Am Diabetes Assoc Pancreatic islets transplanted to treat autoimmune type 1 diabetes often fail to function (primary
nonfunction), likely because of islet β-cell apoptosis. We show that carbon monoxide (CO), a
product of heme oxygenase activity, protects β-cells from apoptosis. Protection is ... Cited by 84 - Related articles - BL Direct - All 17 versions
JL Contreras, G Bilbao, CA Smyth, XL Jiang, DE … - Transplantation, 2001 - journals.lww.com Skip Navigation Links Home > April 27, 2001 - Volume 71 - Issue 8 > CYTOPROTECTION OF
PANCREATIC ISLETS BEFORE AND SOON AFTER TR... ... Contreras, Juan L.; Bilbao,
Guadalupe; Smyth, Cheryl A.; Jiang, Xiao L.; Eckhoff, Devin E.; Jenkins, Stacie M.; ... Cited by 62 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org H Wang, SS Lee, W Gao, E Czismadia, J McDaid, R … - Diabetes, 2005 - Am Diabetes Assoc Treatment of animals or certain cells with carbon monoxide (CO), a product of heme degradation
by heme oxygenase-1 (HO-1), has potent anti-inflammatory and antiapoptotic effects that contribute
to the survival of transplanted organs. We report here that inducing HO-1 in, or ... Cited by 35 - Related articles - All 6 versions
- ►jimmunol.org K Sato, J Balla, L Otterbein, RN Smith, S … - The Journal of …, 2001 - Am Assoc Immnol Mouse-to-rat cardiac transplants survive long term after transient complement depletion by cobra
venom factor and T cell immunosuppression by cyclosporin A. Expression of heme
oxygenase-1 (HO-1) by the graft vasculature is critical to achieve graft survival. In the ... Cited by 328 - Related articles - BL Direct - All 4 versions
