- ►diabetesjournals.org DV Serreze, EA Johnson, HD Chapman, RT … - Diabetes, 2001 - Am Diabetes Assoc A broad repertoire of pancreatic β-cell autoreactive T-cells normally
contributes to the development of type 1 diabetes in NOD mice. However, it has
been unknown if a large reduction in the precursor pool from which ... Cited by 26 - Related articles - BL Direct - All 4 versions
- ►jimmunol.org CM Choisy-Rossi, TM Holl, MA Pierce, HD … - The Journal of Immunology, 2004 - Am Assoc Immnol For unknown reasons, the common MHC class I variants encoded by the H2 g7
haplotype (K d , D b ) aberrantly elicit autoreactive CD8 T cell responses
essential to type 1 diabetes development when expressed in NOD mice, but ... Cited by 27 - Related articles - BL Direct - All 4 versions
TP DiLorenzo, SM Lieberman, T Takaki, S … - Clinical Immunology, 2002 - Elsevier In the NOD mouse model of type 1 diabetes, major histocompatibilitycomplex (MHC)
class I-restricted CD8 + T cells are essential for disease development. However,
the extent of diversity of their antigenic specificities during early ... Cited by 24 - Related articles - BL Direct - All 4 versions
P Santamaria, T Utsugi, BJ Park, N Averill, … - The Journal of Immunology, 1995 - Am Assoc Immnol *Department of Microbiology and Infectious Diseases and Julia McFarlane Diabetes
Research Centre, Faculty of Medicine, University of Calgary, Calgary, Alberta,
Canada, and 'Second Department of Internal Medicine, Gunma University ... Cited by 73 - Related articles - BL Direct - All 3 versions
[CITATION] MHC class I-restricted T cells are required for all but the end stages of diabetes …
D Serreze, EH Letter - Molecular Pathology of Type 1 Diabetes mellitus - books.google.com The'Idd'Genes: What Are They and How Many Are Required for Diabetogenesis? In
order to describe murine chromosomal regions carrying genes capable of
modulating T1D susceptibility when NOD/Lt mice were outcrossed to the ... Cited by 70 - Related articles - BL Direct - All 5 versions
[CITATION] Quantitative thresholds of MHC class II IE expressed on hematopoietically derived APC in …
- ►pnas.org B Anderson, BJ Park, J Verdaguer, A Amrani, … - Proceedings of the National Academy of Sciences, 1999 - National Acad Sciences Spontaneous autoimmune diabetes in nonobese diabetic (NOD) mice is the result of
a CD4 + and CD8 + T cell-dependent autoimmune process directed against the
pancreatic beta cells. CD8 + T cells play a critical role in the initiation ... Cited by 105 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org [PDF] CE Mathews, RT Graser, DV Serreze, EH … - Diabetes, 2000 - Am Diabetes Assoc MHC class II region identity with the H 2 g 7 haplotype of NOD mice. However,
CTS mice were reported to express distinct but undefined MHC class I gene prod-
ucts. Because diabetes frequency was reduced 56% in females of a NOD stock ... Cited by 19 - Related articles - BL Direct - All 3 versions
- ►jimmunol.org RT Graser, TP DiLorenzo, F Wang, GJ … - The Journal of Immunology, 2000 - Am Assoc Immnol Previous work has indicated that an important component for the initiation of
autoimmune insulin-dependent diabetes mellitus (IDDM) in the NOD mouse model
entails MHC class I-restricted CD8 T cell responses against pancreatic ß ... Cited by 90 - Related articles - BL Direct - All 2 versions
