- ►diabetesjournals.org L Rachdi, L El Ghazi, F Bernex, JJ Panthier, P … - Diabetes, 2001 - Am Diabetes Assoc In the pancreas, ligands of receptor tyrosine kinases (RTKs) are thought to be implicated in the
development and function of the islets of Langerhans, which represent the endocrine part of
the pancreas. In a previous study, we randomly screened by reverse transcriptase− ... Cited by 25 - Related articles - BL Direct - All 4 versions
C Öberg-Welsh, M Welsh - Pancreas, 1996 - journals.lww.com Summary: We have previously studied the expression of protein tyrosine kinases in different
preparations of insu- lin producing cells by polymerase chain reaction (PCR). Among the tyrosine
kinases thus identified were the fi- broblast growth factor receptor-4 (FGFR-4), c-Kit, the ... Cited by 20 - Related articles - BL Direct - All 3 versions
NK Yashpal, J Li, R Wang - Developmental Dynamics, 2004 - interscience.wiley.com It has been well documented that there are abundant endocrine progenitor cells in the neonatal
pancreas. However, little is known of their relative proportions or even their phenotypes. The
aim of this study was to examine the normal distribution and characteristics of putative ... Cited by 30 - Related articles - All 3 versions
S LeBras, P Czernichow, R Scharfmann - Diabetologia, 1998 - Springer Summary It is known that during embryonic life, in- teractions between the pancreatic epithelium
and its surrounding mesenchyme are important for proper development of the pancreas. These
interactions are thought to be mediated by soluble factors, which could be, as in other ... Cited by 20 - Related articles - BL Direct - All 3 versions
M Welsh, C Anneren, C Lindholm, V Kriz, C … - Upsala journal of …, 2000 - ncbi.nlm.nih.gov Diabetes mellitus is commonly considered as a disease of a scant beta-cell mass that fails to
respond adequately to the functional demand. Tyrosine kinases may play a role for beta-cell
replication, differentiation (neoformation) and survival. Transfection of beta-cells with DNA ... Cited by 14 - Related articles - BL Direct - All 3 versions
J Li, CG Goodyer, F Fellows, R Wang - … Journal of Biochemistry and Cell Biology, 2006 - Elsevier Stem cell factor (SCF), a progenitor cell growth factor, binds to and activates the c-Kit receptor
tyrosine kinase, which is critical for early stem cell differentiation in haematopoiesis and
gametogenesis. Nothing is known regarding these interactions during islet development ... Cited by 15 - Related articles - All 4 versions
- ►endocrinology-journals.org [PDF] R Wang, J Li, N Yashpal - Journal of Endocrinology, 2004 - Soc Endocrinology The limitation of available islets for transplantation is a major obstacle for the treatment of diabetes
through islet therapy. However, islet monolayers expanded ex vivo may provide a source of progenitor
cells and a model to help understand islet development from precursor cell types. The ... Cited by 24 - Related articles - BL Direct - All 5 versions
K Peters, R Panienka, J Li, G Klöppel, R Wang - Virchows Archiv, 2005 - Springer Abstract Ligation of the pancreatic duct has been shown to induce islet cell neogenesis from
duct cells in the adult rat pancreas. The transcription factors that regulate islet cell neogenesis
and the phenotype of putative precursor cells involved in neogenesis are unknown. We, ... Cited by 30 - Related articles - All 3 versions
- ►diabetesjournals.org T Rosenbaum, MC Sánchez-Soto, M Hiriart - Diabetes, 2001 - Am Diabetes Assoc We analyzed the effect of a brief exposure to nerve growth factor (NGF) on insulin secretion and
macroscopic barium currents of single adult rat pancreatic β-cells. After a 1-h exposure to NGF
(50 ng/ml), single β-cells show a 2.5-fold increase in the insulin secretion index in 5.6 ... Cited by 19 - Related articles - BL Direct - All 9 versions
C Öberg, J Waltenberger, L Claesson-Welsh, M … - Growth …, 1994 - informahealthcare.com Page 1. Gromth Factors, 1994, Vol 10, pp. 115-126 Reprints available directly from the publisher
Photocopying permitted by license only 0 1994 Harwood Academic Publishers GmbH Printed
in Singapore Expression of Protein Tyrosine Kinases in Islet Cells: ... Cited by 69 - Related articles - BL Direct - All 3 versions
