N Maeda, M Takahashi, T Funahashi, S Kihara … - Diabetes, 2001 - Am Diabetes Assoc Insulin resistance and its dreaded consequence, type 2 diabetes, are major
causes of atherosclerosis. Adiponectin is an adipose-specific plasma protein
that possesses anti-atherogenic properties, such as the suppression of ... Cited by 1005 - Related articles - BL Direct - All 4 versions
- ►ahajournals.org K Hotta, T Funahashi, Y Arita, M Takahashi, … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2000 - Am Heart Assoc Abstract—Adiponectin is a novel, adipose-specific protein abundantly present
in the circulation, and it has antiatherogenic properties. We analyzed the
plasma adiponectin concentrations in age- and body mass index ... Cited by 1775 - Related articles - BL Direct - All 7 versions
- ►endojournals.org TP Combs, JA Wagner, J Berger, T Doebber, … - Endocrinology, 2002 - Endocrine Soc MANY STUDIES HAVE shown that thiazolidinediones (TZDs) produce insulin
sensitizing effects in animal models (1, 2, 3, 4) and in insulin-resistant human
subjects (5, 6, 7). It is now clear that TZDs are high affinity ligands for ... Cited by 405 - Related articles - BL Direct - All 4 versions
JG Yu, S Javorschi, AL Hevener, YT … - Diabetes, 2002 - Am Diabetes Assoc The insulin-sensitizing effects of thiazolidinediones are thought to be mediated
through peroxisome proliferator-activated receptor-γ, a nuclear receptor that
is highly abundant in adipose tissue. It has been reported that adipocytes ... Cited by 445 - Related articles - BL Direct - All 5 versions
T Yamauchi, J Kamon, H Waki, Y Terauchi, N … - Nature Medicine, 2001 - alzet.com Insulin resistance induced by high-fat diet and associated with obesity is a
major risk factor for diabetes and cardiovascular dis- eases. Adipose tissue is
not simply a store of excess energy, but also secretes a variety of ... Cited by 2296 - Related articles - View as HTML - BL Direct - All 6 versions
Y Arita, S Kihara, N Ouchi, M Takahashi, K … - Biochemical and Biophysical Research …, 1999 - Elsevier We isolated the human adipose-specific and most abundant gene transcript, apM1
(Maeda, K., et al.,Biochem. Biophys. Res. Commun.221, 286–289, 1996). The apM1
gene product was a kind of soluble matrix protein, which we named ... Cited by 2194 - Related articles - BL Direct - All 5 versions
- ►endojournals.org C Weyer, T Funahashi, S Tanaka, K Hotta, Y … - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc Plasma adiponectin concentration was negatively correlated with percent body fat
(r = -0.43), waist-to-thigh ratio (r = -0.46), fasting plasma insulin
concentration (r = -0.63), and 2-h glucose concentration (r = -0.38), and ... Cited by 1855 - Related articles - BL Direct - All 9 versions
- ►ahajournals.org N Ouchi, S Kihara, Y Arita, K Maeda, H … - Circulation, 1999 - Am Heart Assoc Methods and Results—For the in vitro study, human aortic endothelial cells
(HAECs) were preincubated for 18 hours with the indicated amount of adiponectin,
then exposed to tumor necrosis factor- (TNF- ) (10 U/mL) or vehicle for the ... Cited by 1357 - Related articles - All 6 versions
N Maeda, I Shimomura, K Kishida, H … - Nature medicine, 2002 - nature.com Here we investigated the biological functions of adiponectin/ACRP30, a
fat-derived hormone, by disrupting the gene that encodes it in mice.
Adiponectin/ACRP30-knockout (KO) mice showed delayed clearance of free ... Cited by 1088 - Related articles - BL Direct - All 6 versions
- ►endojournals.org WS Yang, WJ Lee, T Funahashi, S Tanaka, Y … - Journal of Clinical Endocrinology & Metabolism, 2001 - Endocrine Soc Adiponectin, an adipose tissue-specific plasma protein, was recently revealed to
have anti-inflammatory effects on the cellular components of vascular wall. Its
plasma levels were significantly lower in men than in women and lower in ... Cited by 742 - Related articles - BL Direct - All 5 versions
