M Stumvoll, A Fritsche, A Madaus, N Stefan, M … - Diabetes, 2001 - Am Diabetes Assoc Recently, an association of the G allele in UCSNP-43 of calpain 10 with type 2
diabetes and decreased glucose disposal was reported. Calpain 10 is also
expressed in pancreatic islets. It is not known, however, whether and how ... Cited by 51 - Related articles - BL Direct - All 4 versions
J Hoffstedt, M Ryden, P Löfgren, M Orho- … - Diabetologia, 2002 - Springer The genetic and environmental factors that contrib- ute to the development of
Type II (non-insulin de- pendent) diabetes mellitus are not well defined but
resistance of insulin-mediated glucose transport into peripheral tissues ... Cited by 17 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org S Lynn, JC Evans, C White, TM Frayling, AT … - Diabetes, 2002 - Am Diabetes Assoc Variation in the calpain-10 gene (CAPN10) has been shown to be associated with
type 2 diabetes in Mexican-Americans and in at least three Northern European
populations. Studies in nondiabetic Pima Indians showed that one of the ... Cited by 69 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org M Orho-Melander, M Klannemark, MK Svensson … - Diabetes, 2002 - Am Diabetes Assoc The calpain-10 gene (CAPN10) has been associated with type 2 diabetes, but
information on molecular and physiological mechanisms explaining this
association is limited. Here we addressed this question by studying the ... Cited by 77 - Related articles - BL Direct - All 4 versions
- ►endojournals.org E Carlsson, J Fredriksson, L Groop, M … - Journal of Clinical Endocrinology & Metabolism, 2004 - Endocrine Soc Our aim was to investigate the possible role of the type 2 diabetes
susceptibility gene CAPN10 in obesity. A case control study consisting of 235
obese Swedish subjects [body mass index, 40 (35–45) kg/m 2 ] and 235 ... Cited by 41 - Related articles - BL Direct - All 4 versions
- ►endojournals.org J Hoffstedt, E Naslund, P Arner - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Polymorphism in the calpain-10 gene is linked to type 2 diabetes, insulin
resistance, and decreased thermogenesis. In view of the role of ß-adrenoceptors
in thermogenesis we investigated the relationship between ß 1 -, ß 2 -, ... Cited by 31 - Related articles - BL Direct - All 4 versions
- ►endojournals.org SC Elbein, W Chu, Q Ren, C Hemphill, J … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc The calpain-10 gene (CAPN10) has been implicated in type 2 diabetes (T2DM)
susceptibility by both linkage and association in a Hispanic population from
Starr County Texas. Common intronic variants seem to alter CAPN10 mRNA ... Cited by 68 - Related articles - BL Direct - All 6 versions
- ►nih.gov JC Evans, TM Frayling, PG Cassell, PJ Saker, … - The American Journal of Human Genetics, 2001 - Elsevier Variation in CAPN10, the gene encoding the ubiquitously expressed cysteine
protease calpain-10, has been associated with type 2 diabetes in Mexican
Americans and in two northern-European populations, from Finland and ... Cited by 137 - Related articles - BL Direct - All 11 versions
X Yang, RE Pratley, LJ Baier, Y Horikawa, GI … - Molecular genetics and metabolism, 2001 - Elsevier The DNA polymorphism SNP-43 in the calpain-10 gene is associated with insulin
resistance and reduced skeletal muscle transcript in Pima Indians. Alternative
splicing generates transcript isoforms calpain-10a to -10h. We determined ... Cited by 34 - Related articles - BL Direct - All 4 versions
- ►nih.gov LJ Baier, PA Permana, X Yang, RE Pratley, … - Journal of Clinical Investigation, 2000 - Am Soc Clin Investig Previous linkage studies in Mexican-Americans localized a major susceptibility
locus for type 2 diabetes, NIDDM1, to chromosome 2q. This evidence for linkage
to type 2 diabetes was recently found to be associated with a common G→ A ... Cited by 257 - Related articles - BL Direct - All 8 versions
