SA El Mkadem, C Lautier, F Macari, N Molinari, … - Diabetes, 2001 - Am Diabetes Assoc To assess the role of insulin receptor, insulin receptor substrate (IRS)-1, and
IRS-2 genes in insulin resistance, we explored the genomic DNA in women with
polycystic ovary syndrome (PCOS) and a variable degree (mean ± SE) of ... Cited by 69 - Related articles - BL Direct - All 7 versions
- ►endojournals.org [PDF] DA Ehrmann, X Tang, I Yoshiuchi, NJ Cox, GI … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Insulin resistance is a key component in the pathogenesis of polycystic ovary
syndrome (PCOS) and type 2 diabetes. Poly- morphisms in the genes encoding the
insulin receptor sub- strate (IRS) proteins, IRS-1 (Gly972Arg) and IRS-2 ( ... Cited by 66 - Related articles - BL Direct - All 6 versions
- ►endojournals.org DA Ehrmann, PEH Schwarz, M Hara, X Tang, Y … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Nineteen (9%) of the 212 women with PCOS were diabetic and were not included in
the genotype/phenotype analyses. Twelve (63%) of these subjects were
African-American. Phenotypic traits in nondiabetic white probands did not ... Cited by 84 - Related articles - BL Direct - All 8 versions
T Sir-Petermann, F PØrez-Bravo, B Angel, M … - Diabetologia, 2001 - Springer 5. Rabinovitch A (1998) An update on cytokines in the patho- genesis of
insulin-dependent diabetes mellitus Diabetes Metab Rev 14: 129ą151 6. Amrani A,
Verdaguer J, Thiessen S, Bou S, Santamaria P (2000) IL-1alpha, IL-1beta, ... Cited by 25 - Related articles - BL Direct - All 2 versions
- ►endojournals.org L Haddad, JC Evans, N Gharani, C Robertson, K … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Variation within the calpain-10 gene (CAPN10) has been proposed to account for
linkage to type 2 diabetes on chromosome 2q in Mexican-Americans, and
associations with diabetes have been reported in several other populations. ... Cited by 57 - Related articles - BL Direct - All 4 versions
- ►endojournals.org A Gonzalez, E Abril, A Roca, MJ Aragon, MJ … - Journal of Clinical Endocrinology & Metabolism, 2003 - Endocrine Soc THE POLYCYSTIC OVARY syndrome (PCOS) is a common endocrinopathy that is found in
about 5–10% of women of reproductive age (1). Specifically in Spain, a
prospective study reported an overall 6.5% prevalence of PCOS (2). Defining ... Cited by 40 - Related articles - BL Direct - All 4 versions
- ►endojournals.org M Urbanek, X Wu, KR Vickery, LC Kao, LK … - Journal of Clinical Endocrinology & Metabolism, 2000 - Endocrine Soc In an earlier study of 37 candidate genes for polycystic ovary syndrome (PCOS),
the strongest evidence for genetic linkage was found with the region of the
follistatin gene. We have now carried out studies to detect variation in ... Cited by 73 - Related articles - BL Direct - All 4 versions
- ►endojournals.org M Hara, SY Alcoser, A Qaadir, KK … - Journal of Clinical Endocrinology & Metabolism, 2002 - Endocrine Soc Twenty-eight of 218 subjects had the Ala allele, all in the heterozygous state.
The frequency of the Ala allele varied among the groups: 0.01 in
African-Americans, 0.08 in Caucasians, and 0.15 in Hispanics. Nondiabetic ... Cited by 66 - Related articles - BL Direct - All 6 versions
